Clinical trials: Kawasaki Disease
Kawasaki Disease
Measurement of Antibodies in Adults With a History of Kawasaki Disease
Kawasaki disease (KD) is an acute systemic vasculitic syndrome with coronary tropism. It has been reported worldwide, but it is ten times more common in Asian population.
- Trial name
- KAWASAKI Ac (NCT02853266)
- Testing
- laboratory biomarker analysis
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Kawasaki Disease
A Blood Test to Diagnose Kawasaki Disease
A case-control cohort study is being conducted to develop and validate the performance of a whole blood gene expression qPCR test to distinguish KD from other febrile conditions by collecting whole blood sample from KD patients…
- Trial name
- NCT05091229
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- HBI Solutions Inc.
Kawasaki Disease, Coronary Artery Abnormalities
Statins Study in Children of Acute Kawasaki Disease With Coronary Artery Abnormalities
The goal of this observational study is to learn about the safety and effects of atorvastatin in treatment of Chinese Kawasaki disease (KD) children complicated with coronary artery abnormalities (CAA) in acute phase.
- Trial name
- NCT07530640
- Testing
- atorvastatin of dose level 1, atorvastatin of dose level 2, atorvastatin of dose level 3
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Children's Hospital of Fudan University
Mucocutaneous Lymph Node Syndrome
Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017
To investigate the epidemiologic features of Kawasaki disease (KD) in Shanghai from 2013 through 2017 and identify the risk factors for coronary artery lesions.
- Trial name
- NCT03880929
- Testing
- no intervention
- Where
- China
- Volunteers
- 4,533 people
- Sponsor
- Children's Hospital of Fudan University
Kawasaki Disease
Study of Combined Therapy of Aspirin and "IVIG-SN" in Kawasaki Disease
The purpose of this study is to evaluate the safety, efficacy and of Immune Globulin Intravenous (Human) IVIG-SN™ in subjects with kawasaki diseases.
- Trial name
- NCT01524939
- Testing
- immunoglobulin G
- Where
- 7 sites in South Korea
- Volunteers
- 45 people
- Sponsor
- Green Cross Corporation
Kawasaki Disease
Efficacy of Immunoglobulin Plus Infliximab for the Early Regression of Coronary Artery Lesion in Kawasaki Disease
This study evaluates the efficacy of the addition of infliximab to conventional initial treatment (intravenous immunoglobulin [IVIG] plus aspirin) in early regression of coronary artery lesion in patients with Kawasaki disease…
- Trial name
- NCT04535518
- Testing
- IVIG, Aspirin, Infliximab
- Where
- 5 sites in China
- Sponsor
- Children's Hospital of Fudan University
Kawasaki Disease
A Multi-center, Randomized to Compare the Efficacy of IVIG Alone and IVIG Plus High-dose Aspirin in Kawasaki Disease
Kawasaki disease (KD) is an acute febrile systemic vasculitis most commonly seen in children under the age of 5 years old. This trial has been designed as a multi-center, prospective, randomized controlled, evaluator-blinded…
- Trial name
- NCT02951234
- Testing
- IVIG only, IVIG and Aspirin
- Where
- 5 sites in Taiwan
- Volunteers
- 278 people
- Sponsor
- Chang Gung Memorial Hospital
Kawasaki Disease, Appendicitis
Acute Abdomen in Kawasaki Disease
Clinical and histopathological description of three cases of Kawasaki disease with acute abdomen.
- Trial name
- NCT03902262
- Testing
- appendicectomy
- Volunteers
- 3 people
- Sponsor
- National Institute of Pediatrics, Mexico
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University
Kawasaki Disease, Coronary Artery Aneurysm
Pharmacometrics Analysis of Rivaroxaban in Chinese Children Aged Over 2 Years
Based on an established Kawasaki disease cohort database, this prospective, single-center, single-arm, observational study will collect clinical data from children aged 2 years and older with giant coronary artery aneurysms after…
- Conditions
- Kawasaki Disease, Coronary Artery Aneurysm, Rivaroxaban, Anticoagulant Drugs
- Trial name
- NCT06993636
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Kawasaki Disease
The Value of Cardiovascular Imaging in Kawasaki Disease
The goal of this observational study is to assess the cardiovascular injury of Kawasaki disease with multi-modal imaging combined with clinical data.
- Trial name
- NCT06641817
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Kawasaki Disease, Pilot Study
Model-informed Dose Optimization for Rivaroxaban in Children With Giant Coronary Artery Aneurysm After Kawasaki Disease
Based on a population pharmacokinetic model-based dose optimization study, a 15 mg-equivalent, age-, and bodyweight-adjusted dosing regimen for Chinese children with giant coronary artery aneurysms after Kawasaki disease was…
- Conditions
- Kawasaki Disease, Pilot Study, Coronary Artery Aneurysm, Rivaroxaban
- Trial name
- NCT06978439
- Testing
- Rivaroxaban (Xarelto)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Fudan University
Kawasaki Disease, Aneurysm, Coronary
Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease
Background Kawasaki disease (KD) is characterized by fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy.
- Trial name
- NCT02114099
- Testing
- Atorvastatin
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Kawasaki Disease, Atypical Kawasaki Disease
Genetic Determinants of Kawasaki Disease
Kawasaki disease (KD) is an acute self-limited vasculitis of infancy and early childhood. Most patients recover without sequelae although the inflammatory process causes permanent damage to the coronary arteries in 20-25% of…
- Trial name
- NCT03861130
- Where
- United Kingdom
- Volunteers
- 1,379 people
- Sponsor
- Imperial College London
Kawasaki Disease
Prevalence and Early Markers of Atherosclerosis in Adults With a History of Kawasaki Disease
Kawasaki disease (KD) is an acute systemic vasculitic syndrome with coronary tropism. It has been reported worldwide, but it is ten times more common in Asian population.
- Trial name
- Kawasaki (NCT01440075)
- Testing
- Cardiac evaluation
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Mucocutaneous Lymph Node Syndrome
KIDCARE (Kawasaki Disease Comparative Effectiveness Trial)
Kawasaki disease (KD) is a self-limited illness that affects the heart blood vessels (coronary arteries) of infants and children and is now the most common cause of acquired heart disease in children.
- Trial name
- KIDCARE (NCT03065244)
- Testing
- IVIG, Infliximab
- Where
- 29 sites in United States
- Volunteers
- 105 people
- Sponsor
- University of California, San Diego
Kawasaki Disease
Efficacy of Immunoglobulin Plus Prednisolone in Reducing Coronary Artery Lesion in Patients With Kawasaki Disease
This study evaluates the efficacy of the addition of prednisolone to conventional initial treatment (intravenous immunoglobulin [IVIG] plus aspirin) in reducing coronary artery lesion in children with Kawasaki disease (KD) .
- Trial name
- NCT04078568
- Testing
- IVIG, Aspirin, Prednisolone
- Where
- 34 sites in China
- Volunteers
- 3,208 people
- Sponsor
- Children's Hospital of Fudan University
Cardiovascular Diseases, Coronary Aneurysm
Prevention of Coronary Aneurysms in Kawasaki Syndrome
To test the efficacy of intravenous gamma globulin (IVGG) in preventing coronary artery aneurysms in children with Kawasaki Syndrome.
- Conditions
- Cardiovascular Diseases, Coronary Aneurysm, Heart Diseases, Mucocutaneous Lymph Node Syndrome
- Trial name
- NCT00000520
- Testing
- immunoglobulins, intravenous, aspirin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Kawasaki Disease, Inflammation
Characterization of Multisystem Inflammatory Syndrome in Children (MIS-C) and Its Relationship to Kawasaki Disease
Beginning in mid-March 2020, pediatricians in communities in Western Europe, the UK, and the Eastern U.S. that had been severely affected by the Covid-19 pandemic noted an increased number of children presenting with fever and…
- Trial name
- NCT04538495
- Where
- United States
- Volunteers
- 268 people
- Sponsor
- University of California, San Diego
Kawasaki Disease
Epidemiologic Features of Kawasaki Disease in Shanghai From 2008 Through 2012
To investigate the epidemiological pictures of Kawasaki disease (KD) in Shanghai from 2008 through 2012, and illustrate the risk factors of coronary arterial lesions .
- Trial name
- NCT02317913
- Where
- China
- Volunteers
- 2,402 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University