Clinical trials: Joint Pain, Stiffness, Function
Knee Osteoarthritis
The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Osteoarthritis (OA) is the most common form of chronic degenerative joint disease, as well as the main cause of pain and disability in older persons worldwide.
- Trial name
- NCT02917356
- Testing
- Spiritual laying on of hands (SP), Non-spiritual Laying on of Hands, Control group
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Federal University of Juiz de Fora
Knee Osteoarthritis
Improvement in Pain and Function Following a Physiotherapy Program in Older Adults With Knee Osteoarthritis
This study evaluates the combination of a therapeutic exercise program and dry needling in the treatment of knee osteoarthritis in older adults.
- Trial name
- NCT02698072
- Testing
- Therapeutic exercise, Dry needling
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Bruxism, Self-management
Impact of Self-Management Strategies in Self-Reported Bruxism
This study aim to evaluate the effects of a 6-week self-management program on pain, muscle stiffness, and temporomandibular joint (TMJ) functions in sedentary individuals aged 18-40 with bruxism.
- Conditions
- Bruxism, Self-management, Pain, Proprioception
- Trial name
- NCT06914388
- Testing
- Self-Management Strategies
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Joint Pain, Joint Stiffness
Effects of Maine Oils on Joint Stiffness and Pain
Joint pain has a negative effect on quality of life by limiting daily physical activity, and can lead to reduced work capacity, chronic stress, sleep problems, fatigue and reduced social life.
- Conditions
- Joint Pain, Joint Stiffness, Joint Function
- Trial name
- MAR-LEDD (NCT07786181)
- Testing
- Herring oil, Omega-11 concentrate produced from herring oi, Control oil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Rheumatoid Arthritis
Safety and Effect on Pain and Function According to RAPID-3 of IHL-675A in Patients With Rheumatoid Arthritis
The goal of this randomised, double-blind, placebo-controlled Phase II clinical trial is to assess the safety and effect of of IHL-675A in rheumatoid arthritis patients on pain, and function according to RAPID-3.
- Trial name
- CHAPPII (NCT05942911)
- Testing
- IHL-675A, Cannabidiol, Hydroxychloroquine
- Where
- 10 sites in Australia
- Volunteers
- 20 people
- Sponsor
- Incannex Healthcare Ltd
Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand
Effectiveness of an Exercise Program and Education Through a Mobile Application for the Management of Patients With Hand Osteoarthritis and Rheumatoid Arthritis
Strengthening and stretching exercise programs, and recommendations to protect the affected joint have shown to be effective both clinically and economically in conditions such as hand osteoarthritis and hand rheumatoid…
- Conditions
- Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand, Pain, Mobility Limitation
- Trial name
- NCT04263974
- Testing
- Smartphone Application, Conventional treatment
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- University of Seville
Joint Pain, Stiffness, Function
Instaflex and Joint Pain in Community Adults
The primary purpose of this study is to assess the effect of 8-weeks ingestion of the Instaflex Joint Support supplement (Direct Digital, Charlotte, NC) compared to placebo on joint pain, stiffness, and function (questionnaires…
- Trial name
- NCT01956500
- Testing
- Instaflex
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Osteoarthritis
Effects of Modified T'ai Chi on Symptoms in Older Adults With Osteoarthritis
The purpose of this study was to evaluate the effects of TC for Arthritis on physical function, pain, and stiffness in older adults with knee/hip OA. Two hypotheses were tested: 1.
- Trial name
- NCT00485043
- Testing
- Modified T'ai Chi: T'ai Chi for Arthritis
- Volunteers
- 30 people
- Sponsor
- University of Kansas
Post Operative Pain
Comparative Effects of Hold Relax Technique and Mulligan Mobilization in Post Operative Knee Joint
The aim of this study is to investigate the comparative effects of hold relax technique and mulligan mobilization on pain, ROM and function in post operative knee joint.
- Trial name
- NCT05356663
- Testing
- Mulligan Mobilization, Hold Relax
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Bruxism, Posture
Determining the Relationship Between Posture, Muscle Stiffness, Pain, and Jaw Functionality in Individuals With Bruxism
Bruxism is a repetitive jaw-muscle activity characterized by teeth clenching and/or grinding, often associated with temporomandibular joint dysfunction, pain, and impaired jaw function.
- Conditions
- Bruxism, Posture, Sleep Quality, Pain Assessment
- Trial name
- Bruxism (NCT07560670)
- Testing
- Bruxism Assessment Form, Clinical Examination, Patient Evaluation Form
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Pomegranate (P. Granatum) Peel Compress
The Effect of Pomegranate (Punica Granatum L.) Peel Compress Application on Pain and Physical Function Status
Osteoarthritis is the most common type of arthritis among rheumatologic diseases. Complementary therapies are one of the effective methods for pain control. This study was planned as a randomized controlled experimental study.
- Trial name
- Pomegranate (NCT06034106)
- Testing
- Pomegranate (Punica granatum) peel compress, Hot compress
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Osteoarthritis, Knee, Quality of Life
Yoga for Managing Knee Osteoarthritis in Older Women: a Feasibility Study
The study hypothesized that it is feasible and safe to use Hatha yoga in older women with knee osteoarthritis (OA), and practicing Hatha yoga regularly will help reduce pain and stiffness, enhance physical function, and improve…
- Conditions
- Osteoarthritis, Knee, Quality of Life, Poor Quality Sleep, Physical Impairment
- Trial name
- NCT01832155
- Testing
- Hatha yoga
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Pain
Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders
Joints and muscles disorders are common symptoms in the population. They are characterized by swelling, pain, functional impairment and morning stiffness.
- Trial name
- Easykrill (NCT02318875)
- Testing
- Kritech administration
- Where
- France
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vivatech
Neck Pain
Bio-mechanical Reasoning and Lateral Specificity of Upper Cervical Joint Mobilization
Participants with limited neck rotation are recruited to determine if manual therapy (joint stretching) techniques applied in a bio-mechanically correct sequence will improve neck motion, function and pain better than if the…
- Trial name
- NCT04054869
- Testing
- Bio-mechanically correct manual therapy at the cervical atlanto-axial joints, Bio-mechanically in-correct manual therapy at the cervical atlanto-axial joints
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrews University
Pain, Stiffness
Telerehabilitation for Knee Osteoarthritis: Study Protocol
Patient Recruitment and Enrolment All patients diagnosed with knee OA who present at Artros Medical Center for an orthopaedic specialist consultation will undergo a radiological examination.
- Conditions
- Pain, Stiffness, Physical Function
- Trial name
- NCT07137897
- Testing
- Telerehabilitation, Control group
- Where
- Slovenia
- Volunteers
- 118 people
- Sponsor
- University of Novo Mesto
Degenerative Joint Disease
Hyaluronic Acid and Adelmidrol (Hyadrol®) in Patients With Degenerative Joint Disease
Osteoarthritis is a major cause of chronic musculoskeletal pain. Behind this disorder there is a process of chronic neuroinflammation due to the overactivation of mast cells at the tissue level.
- Trial name
- NCT06506656
- Testing
- Hyadrol®
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- University of Roma La Sapienza
Arthritis, Rheumatoid
Study in Patients With Moderated to Severe Rheumatoid Arthritis Who Have Failed to Combination Therapy of Conventional Disease-modifying Antirheumatic Drugs (cDMARDs) to cDMARD Plus ANti-TNF Versus cDMARDs in Real World
This study will be conducted to observe the disease activity change of Conventional Disease Modifying Anti-Rheumatic Drugs (cDMARD) plus anti-tumour necrosis factor (anti-TNF) from baseline to 6 months compared with cDMARDs, as…
- Trial name
- HUMAN (NCT03264703)
- Where
- 15 sites in South Korea
- Volunteers
- 212 people
- Sponsor
- Eisai Korea Inc.
Pain, Pain, Postoperative
Effects of IASTM With and Without CT on Pain, ROM, and Functional Disability in Post-Operative Knee Stiffness Patients
This single-blinded randomized control study aimed to determine the effects of instrumental soft tissue mobilization technique with and without conservative treatment in post-operative knee stiffness patients.
- Conditions
- Pain, Pain, Postoperative, Pain, Joint, Knee Pain Chronic
- Trial name
- NCT06551922
- Testing
- Instrumental Soft Tissue Mobilization Technique with Conservative Treatment, Conservative Treatment
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore
Joint Discomfort, Joint Pain, Stiffness, Function
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women
The goal of this interventional study is to evaluate whether the study product can help improve quality of life and reduce common menopause symptoms-such as joint discomfort, hot flashes and night sweats-in women aged 50-70.
- Conditions
- Joint Discomfort, Joint Pain, Stiffness, Function, Joint Pain, Hot Flashes
- Trial name
- NCT07238478
- Testing
- JDS-HF3.0
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bonafide Health