Clinical trials: Joint Contracture
Restrictive Burn Scars
Pilot Study of Azficel-T for the Treatment of Restrictive Burn Scars
This Phase II, double-blind, randomized, placebo-controlled pilot study is designed to determine whether injection of autologous fibroblasts can increase the mobility (decrease the restriction) of burn scars.
- Trial name
- NCT01858753
- Testing
- Autologous fibroblasts
- Where
- 9 sites in United States
- Volunteers
- 5 people
- Sponsor
- Castle Creek Biosciences, LLC.
Contracture
Collagenase Injection for Contracture Management
The overall goal is to investigate the effectiveness of a novel intervention - Collagenase injection, for contracture management in patients with neurological impairments, such as stroke, brain injury, and spinal cord injury.
- Trial name
- NCT07693556
- Testing
- Active XIAFLEX Collagenase injection
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Contracture of Muscle, Thigh
The Effect of Reducing Soreness in Marathon Runners
Delayed onset muscle soreness is defined as the sensition of pain and discomfort in skeletal muscles that occurs after eccentric muscle actions or strenuous exercise like a marathon.
- Trial name
- NCT01512082
- Testing
- Pulsed electromagnetic field devices
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Knee Osteoarthritis, Flexion Contracture of Knees
IPICK Blocking for TKA With Moderate Flexion Contracture
Clinical effect of intermittent multiple IPICK blocking on TKA for knee osteoarthritis with flexion contracture between 5 ° and 10 °
- Conditions
- Knee Osteoarthritis, Flexion Contracture of Knees, Anesthesia, Local
- Trial name
- NCT04603950
- Testing
- CACB+IPACK, CACB
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Hospital of Jilin University
Stroke, Muscle Spasticity
Early Use of Botulinum Toxin in Spasticity Post Stroke.
Patients who survive a stroke are often left with an arm that cannot be used. One reason for this is that the muscles affected by the stroke become overactive. This is known as spasticity.
- Conditions
- Stroke, Muscle Spasticity, Contracture
- Trial name
- EUBoSS (NCT01882556)
- Testing
- onabotulinumtoxinA
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Contracture of Muscle, Thigh, Muscle Rigidity
Differents Intensities of Passive Stretching on ROM, Neuromuscular and Performance in Soccer Players: A Blinded RCT
Intensity is a "qualitative" variable of a muscle stretching protocol, which is very little studied due to its inherent characteristic of the individual being stretched.
- Conditions
- Contracture of Muscle, Thigh, Muscle Rigidity, Strain of Hamstring Muscle (Disorder)
- Trial name
- NCT03150563
- Testing
- Passive static stretch
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Muscle Fatigue
Electrical Stimulation vs. Static Stretching in the Leg Muscles
The retraction of the posterior leg muscles consists of a shortening of the muscle fibers that limits ankle dorsiflexion. The objective of this randomized controlled clinical trial (RCT) with a double-blind technique and…
- Trial name
- NCT06626698
- Testing
- Static stretching, Electrical muscle elongation
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- University of Seville
Deep Vein Thrombosis, Ankle Joint Contracture
Robotic Sock Technology for Prevention of Deep Vein Thrombosis and Joint Contracture
The research team's aim is to investigate the effects of the team's soft robotic socks in providing assisted ankle dorsiflexion-plantarflexion and promoting venous blood flow in stroke patients.
- Trial name
- NCT03068338
- Testing
- Robotic Sock, Intermittent pneumatic compression
- Where
- Singapore
- Volunteers
- 17 people
- Sponsor
- National University Hospital, Singapore
Joint Contracture, Contracture
Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft
The purpose of this study is to compare how often joint contractures in the arms and legs come back after two common types of reconstructive surgery: Z-plasty and full-thickness skin graft (FTSG).
- Conditions
- Joint Contracture, Contracture, Cicatrix, Burn Scar Contractures
- Trial name
- NCT07885046
- Testing
- Z-Plasty, Full-Thickness Skin Graft
- Volunteers
- 300 people
- Sponsor
- Universitas Sebelas Maret
Cerebral Palsy
Early Intervention in Infants With Cerebral Palsy
Contractures are a frequent cause of reduced mobility in children with Cerebral palsy (CP) already at the age of 2-3 years. Reduced muscle use and muscle growth have been suggested as key factors in the development of…
- Trial name
- CONTRACT (NCT04250454)
- Testing
- CONTRACT
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Copenhagen
Contracture, Hand
Effects of Paraffin Wax Therapy vs METs in Post Burn Hand Contractures
The degree of the burn and the rate of scar development during healing are the main determinants of loss of hand function following thermal injury.
- Trial name
- NCT06198062
- Testing
- Paraffin wax bath therapy, Paraffin Wax Bath Therapy and Muscle Energy Techniques
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cerebral Palsy, Muscle Contracture
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contracture, Spasticity, Muscle
- Trial name
- CPMuscleSL (NCT05518565)
- Testing
- No intervention
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Eva Ponten
Internal Rotation Contracture-shoulder, Articulation Disorders
Internal Rotation Deficit of the Glenohumeral Joint in Advanced-level Handball Players
The main objective of this study is to estimate the incidence and prevalence of Internal Rotation Deficit (IRD) defined by a measure of IRD 2 (Internal Rotation Deficit in position 2) strictly greater than 20 ° in a population of…
- Conditions
- Internal Rotation Contracture-shoulder, Articulation Disorders, Athletic Injuries
- Trial name
- GIRDH (NCT02011243)
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Joint Contractures
Investigations of Mechanisms and Treatment in Post-traumatic Joint Contractures
Injured joints, especially at the elbow, are at risk for permanent motion loss, also known as joint contractures. Joint contractures limit the function of an elbow and are a recognized complication that occurs often after a…
- Trial name
- Ketotifen (NCT01902017)
- Testing
- Ketotifen
- Where
- 3 sites in Canada
- Volunteers
- 152 people
- Sponsor
- University of Calgary
Hemophilia, Elbow Joint Contracture
Efficacy of Strength Training in Improving Elbow Range of Motion and Function in Adults With Hemophilia
This is a research study of adults with hemophilia that have limitations in elbow joint motion that is the result of bleeding into the joint.
- Trial name
- NCT03842605
- Testing
- Strength training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Dupuytren's Contracture
Phase II Randomized Study of Collagenase in Patients With Residual Type Dupuytren's Disease
OBJECTIVES: Evaluate the safety and efficacy of collagenase in improving flexion deformity, range of motion, and grip strength in patients with residual Dupuytren's disease.
- Trial name
- NCT00004409
- Testing
- collagenase
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- State University of New York
Proximal Interphalangeal Finger Joint Contractures
High Doses of Total End Range Time Offer Better Results Than Low Doses Treating Proximal Interphalangeal Joint Stiffness
Elastic Tension Digital Neoprene Orthosis is a new device that can increase the dose of treatment of the proximal interphalangeal flexion contractures.
- Trial name
- NCT05625451
- Testing
- Elastic Tension Digital Neoprene Orthosis
- Where
- Spain
- Volunteers
- 91 people
- Sponsor
- Vicenç Punsola Izard
Contracture, Spasticity, Muscle
Effect of Cryoneurolysis on Pain in Patients With Hand Contracture.
Contracture which is defined as a limitation of the maximum passive range of motion due to changes in periarticular soft tissue can contributes to severe pain and increased disabilities.
- Trial name
- NCT06051656
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Vancouver Island Health Authority
Dupuytren's Contracture
Phase III Randomized Study of Collagenase in Patients With Residual Stage Dupuytren's Disease
OBJECTIVES: I. Compare the safety and efficacy of clostridial collagenase vs placebo in terms of improving the degree of flexion deformity, range of finger motion, and grip strength in patients with residual stage Dupuytren's…
- Trial name
- NCT00014742
- Testing
- collagenase
- Volunteers
- 72 people
- Sponsor
- State University of New York
Hallux Limitus
Contracture Reduction Following Bunionectomy: a Longitudinal, Controlled Trial
To determine the efficacy of Metatarsal Dynasplint Sytem (MTP) in reducing contracture of hallux limitus secondary to Bunionectomy, in a longitudinal, controlled trial.
- Trial name
- Bunionectomy (NCT01589679)
- Testing
- standard of care, Metarsal Dynasplint
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Dynasplint Systems, Inc.