Clinical trials: Jaundice, Neonatal
Jaundice Neonatal
The Risk of Hyperbilirubinemia in Term Newborns After Placental Transfusion
Delayed cord clamping (DCC) has been a subject of extensive research for the last couple of years. Based on published data, numerous neonatal benefits have been suggested such as increased hemoglobin and ferritin levels both at…
- Trial name
- NCT02625688
- Testing
- Delayed cord clamping, Cord milking, Early cord clamping
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Preterm Infant, Jaundice, Neonatal
BiLirubin Decrease Under Phototherapy Exposure in the Preterm Newborn in Incubator
Phototherapy is routinely used in neonatal intensive care units for the treatment of jaundice. Guidelines focus mainly on bilirubin serum levels to start the phototherapy.
- Conditions
- Preterm Infant, Jaundice, Neonatal, Phototherapy
- Trial name
- BLUE (NCT03942757)
- Testing
- bilirubin serum level determination, Phototherapy
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Neonatal Hyperbilirubinemia
Reverse Phototherapy With Super Light-emitting Diode(Super-LED) for Hyperbilirubinemia in Term and Late Preterm Infants
The aim of this study is to compare the efficacy of super-LED reverse phototherapy with the fluorescent reverse phototherapy in term and late preterm newborns.
- Trial name
- NCT01340339
- Testing
- Phototherapy
- Where
- Brazil
- Volunteers
- 144 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Jaundice, Neonatal, Neonatal Diseases and Abnormalities
Evaluation of Bili-ruler, a Low-cost, Plastic Icterometer for Community-based Screening of Jaundice in Newborns
Newborn jaundice, or accumulation of bilirubin molecules in blood, affects 60-80% of newborns and, in severe cases, places newborns at risk of brain damage and death.
- Conditions
- Jaundice, Neonatal, Neonatal Diseases and Abnormalities, Neonatal Hyperbilirubinemia, Screening Tool
- Trial name
- NCT06687746
- Testing
- Bili-ruler
- Where
- 5 sites in India, Kenya and 2 more
- Volunteers
- 4,060 people, healthy volunteers welcome
- Sponsor
- George Washington University
Jaundice
Value of Transcutaneous Bilirubin Devices
The goal of this observational study is to compare the value of transcutaneous bilirubin devices versus serum bilirubin in jaundiced neonates
- Trial name
- NCT06232174
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Anemia, Iron Deficiency
Effect of Timing of Umbilical Cord Clamping on Anaemia at 8 and 12 Months and Later Neurodevelopment
The investigators plan a study to randomize 540 children in Nepal to early (≤30 seconds) or late (≥180 seconds) clamping of the umbilical cord at birth.
- Conditions
- Anemia, Iron Deficiency, Neonatal Jaundice
- Trial name
- NCT02222805
- Testing
- Early (≤30 seconds) cord clamping, Delayed (≤180 seconds) cord clamping
- Where
- Nepal
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Hyperbilirubinemia
Transcutaneous Bilirubinometry in Healthy Term and Near-Term Neonates
Objectives: Bilirubin measured by transcutaneous bilirubinometry (TcB) is a reasonably accurate estimate of serum total bilirubin (STB).
- Trial name
- NCT00653874
- Testing
- BiliChek (jaundice assessment), Transcutaneous bilirubinometry (TcB), Clinical asessment of bilirubin (CaB)
- Where
- India
- Volunteers
- 617 people
- Sponsor
- All India Institute of Medical Sciences
Neonatal Jaundice
Efficacy of Zinc in Reducing Hyperbilirubinemia Among High Risk Neonates - A Double Blind Randomized Trial
The purpose of this study is to determine the effect of 10 mg of oral zinc given daily between days 2 and 7 of life to term or near term neonates with serum bilirubin levels of more than 6 mg/dL at 24 ± 6 hours of life on…
- Trial name
- NCT00692224
- Testing
- zinc gluconate
- Where
- India
- Volunteers
- 294 people
- Sponsor
- All India Institute of Medical Sciences
Hyperbilirubinemia, Jaundice
Demographic, Metabolic, and Genomic Description of Neonates With Severe Hyperbilirubinemia
The purpose of this study is to compare the demographic, metabolic, and genomic characteristics of patients who develop severe hyperbilirubinemia to patients who never developed a significant bilirubin level.
- Trial name
- NCT00383318
- Testing
- Gene mutation sample
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Jaundice, Neonatal
Associations of Nighttime Light Exposure During Pregnancy With Neonatal Jaundice：a Multi-centre Prospective Study in China
Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.
- Trial name
- jaundice (NCT03805165)
- Where
- China
- Volunteers
- 2,977 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Uncomplicated Neonatal Hyperbilirubinemia
Comparison Between Turquoise and Blue Light in Treatment of Neonatal Jaundice Using Light Emission Diodes
The optimal wavelength for phototherapy for neonatal jaundice remains to be clarified by clinical studies. Previous iv vivo studies have shown that turquoise light at wavelength about 490 nm is more efficacious than blue light at…
- Trial name
- NCT02154165
- Testing
- Phototherapy
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Neonatal Hyperbilirubinemia, Neonatal Jaundice
Hat-Type Glasses Intervention in Phototherapy-Related Newborns
Aim : "This study aims to determine the effect of using a cap with protective eye goggles in term newborns undergoing phototherapy on the duration of phototherapy, the newborns' comfort level, and parental satisfaction." Study…
- Trial name
- NCT07690930
- Testing
- Hat-with-Goggles Eye Protection Device
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Karamanoğlu Mehmetbey University
Newborn Jaundice
Aluminum Foil Reflector on Phototherapy for Newborn with Jaundice
Hyperbilirubinemia is defined as the presence of bilirubin in the serum of newborns at levels exceeding the normal range. It is the most common problem among healthy newborns, with an incidence of approximately 40% to 60% in…
- Trial name
- NCT06837935
- Testing
- Aluminum Foil Reflector
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Neonatal Cholestasis, Neonatal Jaundice
Liver Biopsy in Diagnosis Neonatal Jaundice
1. Identification and characterization of histopathological features of liver in cases of PNJ. 2. Assessment of key histological features in liver biopsy as diagnostic parameters in differentiating intra-hepatic and extra-hepatic…
- Trial name
- NCT06628726
- Testing
- Liver biopsy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Neonatal Jaundice, Hyperbilirubinemia
Compassionate Use of Stanate (TM) [Stannsoporfin]
The purpose of this protocol is to make Stanate (TM) [stannsoporfin, tin-mesoporphyrin] available to infants who meet the following criteria: 1.
- Trial name
- NCT00076960
- Testing
- Stanate (TM) [stannsoporfin, tin-mesoporphyrin]
- Where
- United States
- Sponsor
- InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Neonatal Jaundice
the Difference of Follow-up Methods of Neonatal Jaundice
The goal of this observational study is to compare the effectiveness and efficiency for precaution of severe hyperbilirubinemia in neonate by different follow-up methods of neonatal jaundice.
- Trial name
- NJFU (NCT06075290)
- Testing
- internet plus model, control
- Where
- 3 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Guizhou Provincial People's Hospital
Neonatal Jaundice
mHealth to Screen for Neonatal Jaundice in Low-resource Mexican Settings: a Feasibility Study
Neonatal jaundice (NNJ) is a common condition in newborns during the first week of life due to increased levels of bilirubin. Usually, it resolves without consequences after 7 to 10 days.
- Trial name
- JAUND-EASE (NCT06073444)
- Testing
- Picterus JP
- Where
- Mexico
- Volunteers
- 611 people
- Sponsor
- Norwegian University of Science and Technology
Neonatal Jaundice, Neonatal Hyperbilirubinemia
Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Population in Botswana
This project aims to test a novel smartphone application, Picterus, which provides a cheaper, patient-friendly, and more readily means of neonatal jaundice detection.
- Trial name
- BILIAPPBOT (NCT06399146)
- Testing
- Picterus App
- Where
- Botswana
- Volunteers
- 150 people
- Sponsor
- Hillerod Hospital, Denmark
Jaundice, Neonatal
Comparison Of Fenofibrate Vs Phenobarbitone As Adjunct To Phototherapy In Reducing Total Serum Bilirubin In Indirect Hyperbilirubinemia In Neonates
This is a prospective, randomized, open-label controlled trial comparing fenofibrate (10 mg/kg) and phenobarbitone (3 mg/kg) as adjuncts to conventional phototherapy in neonates with unconjugated hyperbilirubinemia.
- Trial name
- NCT07774741
- Testing
- Fenofibrate + Phototherapy, Phenobarbitone + Phototherapy
- Volunteers
- 70 people
- Sponsor
- Rubab Fatima