Clinical trials: Itch Scarring
Post-burn Innervation
Study of the Cutaneous Reinnervation After Burn
The aim of this study is to understand why the regeneration of the cutaneous sensory nerve fibers is poor in post-burn scar. The presence or the lack of several molecular factors known to regulate neuronal cell development will…
- Trial name
- NERVAL (NCT02356354)
- Testing
- Skin biopsy
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Scald Burn, Itching
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns
Pain, itching, hypertrophic scar formation after wound healing in burn patients complications, sleep disturbances in patients, anxiety, depression, and daily life It may disrupt activities and deterioration in quality of life.
- Conditions
- Scald Burn, Itching, Hypertrophic Scarring
- Trial name
- NCT06104540
- Testing
- Experimental I liquid vaseline groups, Experimental II extra virgin olive oil groups, Control Croup
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Wound Healing, Wound Infection
Acticoat Absorbent and BCT Antimicrobial for STSG Donor Site on Thigh
This study aims to compare the effectiveness of two wound dressings, Acticoat Absorbent (AA) and BCT Antimicrobial (BCT) on Split Thickness Skin Graft (STSG) donor site.
- Conditions
- Wound Healing, Wound Infection, Pain, Pruritus
- Trial name
- NCT01769144
- Testing
- Acticoat Absorbent, BCT
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Burns, Scar Pruritus
Exploring the Correlation Between Post Traumatic Stress Disorder, Perceived Stress and Scar Pruritus in Burn Patients
Pruritus, post traumatic stress disorder and perceived stress are common issues in burn patients. The correlation between the three is unclear so far.
- Conditions
- Burns, Scar Pruritus, Post Traumatic Stress Disorder, Perceived Stress
- Trial name
- NCT05885321
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- National Taiwan University Hospital
Burn Scar, Itch Scarring
Novel Strategies for Reducing Burn Scar Itch
The purpose of the study is to see whether using diphenhydramine (Benadryl), famotidine (Pepcid), and cromolyn sodium will decrease burn scar itch.
- Conditions
- Burn Scar, Itch Scarring, Wound
- Trial name
- NCT06801626
- Testing
- Famotidine and 4% topical cromolyn sodium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burn Scar
Effect of Pulsed Electromagnetic Field on Pruritus in Burn Scars
This study will be conducted to evaluate the effectiveness of pulsed electromagnetic field therapy in pruritus in patients with burn scars.
- Trial name
- PEM (NCT07443358)
- Testing
- pulsed electromagnetic field therapy, standard care
- Volunteers
- 40 people
- Sponsor
- Cairo University
Scar Keloid, Hypertrophic Scar
Botulinum Toxins Intralesional Injection for Scar Pain
Botulinum toxins has been approved by the FDA to treat chronic migraine. Botox had been shown to inhibiting the release of inflammatory mediators and peripheral neurotransmitters from sensory nerve to treat neuropathic pain.
- Trial name
- NCT03982862
- Testing
- Triamcinolone, Lidocaine, Botulinum toxin A
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Kaohsiung Medical University
Itchiness, Hypertrophic Scar
The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial
Hypertrophic scar, a disfiguring tissue reaction to trauma, occurred in around 20 % of the population. The patients with hypertrophic scar usually seek medical assistance not just for the annoying appearance but mostly due to the…
- Conditions
- Itchiness, Hypertrophic Scar, Botulinum Toxin
- Trial name
- NCT02168634
- Testing
- Botulinum Toxins
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Anus Diseases, Gastrointestinal Diseases
Evaluation of the Effectiveness of a Topical Medical Device in Wound Healing and Symptom Relief in the Postoperative Period of Open Excisional Hemorrhoidectomy (The Emor Study)
This multicenter randomized controlled phase IV trial aims to compare the clinical efficacy of a gel containing a Propionibacterium extract and a gel with hyaluronic acid and silver sulfadiazine in the degree of epithelialization…
- Conditions
- Anus Diseases, Gastrointestinal Diseases, Intestinal Diseases, Cicatrization
- Trial name
- NCT06872151
- Testing
- Gel containing a Propionibacterium extract, Hyaluronic acid and silver sulfadiazine
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- University of Cagliari
Cicatrix, Post-Surgical Complication
Class I Medical Device on Post-surgical Scars
To compare the effect of a class I pullulan based medical device containing Allium cepa \& HA versus a class I medical device silicone gel on new post-surgical wounds
- Conditions
- Cicatrix, Post-Surgical Complication, Scar Itching, Keloid
- Trial name
- NCT05412745
- Testing
- Kaloidon Plus, silicone gel
- Where
- 2 sites in Italy
- Volunteers
- 64 people
- Sponsor
- University of Rome Tor Vergata
Hypertrophic Scar, Burn Scar
Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser
Hypertrophic Burn Scars (HTBS) are often treated with Fractional CO2 laser therapy to improve cosmetic appearance. It has been noted that this leads to a reduction in the pain and itch associated with this type of scars.
- Trial name
- NCT04364217
- Testing
- Luminis ultrapulse fractional ablative carbon dioxide laser
- Where
- United States
- Sponsor
- Massachusetts General Hospital