Clinical trials: Ischemia Preconditioning
Hemodialysis, Ischemia Preconditioning
Assessment of the Impact of Repeated Ischemic Preconditioning Episodes on Hemodynamic and Metabolic Parameters in Patients at Various Stages of Chronic Kidney Disease
The aim of our study is to evaluate the impact of repeated episodes of ischemic quenching on changes in blood pressure, heart rate and laboratory parameters of inflammation in patients with kidney diseases.
- Conditions
- Hemodialysis, Ischemia Preconditioning, Chronic Kidney Disease, Blood Pressure Disorders
- Trial name
- NCT07746102
- Testing
- Preconditioning with control ischemic episodes
- Where
- 2 sites in Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Ischemic Preconditioning, Coenzyme Q Deficiency
Effect of CoQ10 on the Endocrine Function of Skeletal Muscle
Recent studies have also shown that repeated episodes of ischemia, followed by reperfusion (IPC), can contribute to the development of adaptive changes not only in the area of the heart muscle, but also in the structure of the…
- Conditions
- Ischemic Preconditioning, Coenzyme Q Deficiency, Exercise Training
- Trial name
- NCT05412888
- Testing
- CoQ10 supplementation, Ischemic preconditioning training, IPC training combined with CoQ10 supplementation
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Limb Ischemia, Ischemic Preconditioning
Model System for Transient Forearm Blood Vessel Dysfunction
This study will develop a model system that can be used to test medications for improving the ability of blood vessels to resist damage from diseases such as heart attack and stroke.
- Trial name
- NCT00453531
- Testing
- Limb Ischemia, Acetylcholine
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Vascular Surgery, Ischemia-reperfusion
Effects of Ischemic Preconditioning After Aortic Clamping
Open surgery for aneurysmal aortic disease can lead to cardiac, renal, pulmonary or muscular complications, essentially due to the aortic clamping. Ischemic preconditioning can be useful in order to decrease these complications.
- Conditions
- Vascular Surgery, Ischemia-reperfusion, Ischemia Preconditioning
- Trial name
- NCT02254642
- Testing
- Ischemic preconditioning during aortic clamping, Procedure/Surgery: usual surgery
- Where
- 4 sites in France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Strasbourg, France
Ischemic Preconditioning, Acute Kidney Injury
Remote Ischemic Preconditioning During Lower Limb Revascularization
The aim of this study is to evaluate the role of remote ischemic preconditioning (RIPC) in preventing acute kidney injury after lower limb revascularization.
- Conditions
- Ischemic Preconditioning, Acute Kidney Injury, Limb Ischemia
- Trial name
- NCT04016857
- Testing
- RIPC, Control
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Messina
Moyamoya Disease, Remote Ischemic Preconditioning
Effects of Remote Ischemic Pre-Conditioning in Moyamoya Disease Patients
In the present study, investigators evaluated whether RIPC reduce the major neurological complications in adult moyamoya disease patients undergoing encephaloduroarteriosynangiosis (EDAS).
- Trial name
- RIME (NCT04064658)
- Testing
- Remote ischemic preconditioning, Encephaloduroarteriosynangiosis
- Where
- 2 sites in China
- Volunteers
- 328 people
- Sponsor
- Beijing Tiantan Hospital
Caffeine, Ischemic Preconditioning
The Effect of Caffeine on Ischemic Preconditioning
Ischaemic preconditioning (IP) describes the phenomenon that brief periods of ischaemia render the (myocardial) muscle more resistant to a subsequent more prolonged period of ischaemia and reperfusion.
- Conditions
- Caffeine, Ischemic Preconditioning, Ischemia-Reperfusion Injury
- Trial name
- NCT00184912
- Testing
- caffeine, Technetium-TC99m-labeled Annexin A5, ten minutes forearm ischemia
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center