Clinical trials: Irritable Bowel Disease
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Randomized Controlled Trial of Citizen-targeted Evidence-based Resources
The purpose of this study is to determine whether an online resource developed to aid health consumers in making health decisions and better support them to seek quality evidence before other evidence is effective in the context…
- Trial name
- NCT04693780
- Testing
- Structured guide, List
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Irritable Bowel Syndrome With Constipation (IBS-C)
A Study of the Effect of SYN-010 on Subjects With IBS-C
A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Dose Study of the Effect of Two Dosage Strengths of SYN-010 Compared with Placebo on Breath Methane Production in Breath Methane-Positive Subjects with…
- Trial name
- NCT02495623
- Testing
- SYN-010 21 mg, SYN-010 42 mg
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Theriva Biologics, Inc.
Irritable Bowel Syndrome With Constipation (IBS-C)
Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients
The purpose of this study is to understand how a drug called Linaclotide improves bowel function and abdominal pain in patients with Irritable Bowel Syndrome with Constipation (IBS-C) as well as to examine whether Linaclotide…
- Trial name
- NCT02078323
- Testing
- Linaclotide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Augusta University
Shigella Sonnei Infection
The Long Term Clinical Course of Postinfectious Irritable Bowel Syndrome After Shigellosis; A 10 Year Follow up Study
Background: The incidence of postinfectious irritable bowel syndrome (PI-IBS) was reported to be in the range of 5-30%, but limited number of long-term follow-up results.
- Trial name
- NCT02516683
- Testing
- Shigella sonnei infection
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Irritable Bowel Syndrome, Dyspepsia
Visible Abdominal Distension
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06369753
- Testing
- Biofeedback
- Where
- 7 sites in United States, Canada and 5 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Irritable Bowel Syndrome
Internet-delivered Exposure-based Cognitive Behavior Therapy for Irritable Bowel Syndrome - a Cohort Effectiveness Study
The main purpose of the study is to investigate the clinical real-world effectiveness of a specific exposure based psychological treatment for irritable bowel syndrome (IBS).
- Trial name
- NCT05328245
- Volunteers
- 319 people
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome
Effects of Vivatlac Synbiotic on Gut Micribiota of IBS Patients
Multi-center, randomized, double-blind, placebo-controlled, 12 weeks trial investigating the effects of a nine-strain synbiotic (Vivatlac Synbiotikum) on the gut microbiota of IBS patients
- Trial name
- ViIBS3 (NCT07235228)
- Testing
- Vivatlac Synbiotic
- Where
- 2 sites in Poland
- Volunteers
- 20 people
- Sponsor
- The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz
IBS - Irritable Bowel Syndrome
Treatment Efficacy of Low FODMAP Versus Low Lactose Diet in IBS Patients
A low FODMAP diet (LFD) has become a standard treatment in irritable bowel syndrome (IBS) patients. Compliant adherence to a LFD is challenging.
- Trial name
- NCT04543474
- Testing
- Low Lactose Diet, Low FODMAP Diet
- Volunteers
- 30 people
- Sponsor
- Cantonal Hospital of St. Gallen
Irritable Bowel Syndrome, Diarrhea
Utility of the Administration of Chesnut and Quebracho Extract for Irritable Bowel Syndrome Diarrhea Predominant
Irritable bowel syndrome is a highly prevalent disorder and consumes many health resources. Its physiopathogenesis is multifactorial.
- Trial name
- NCT05207618
- Testing
- ARBOX (QUEBRACHO AND CHESNUT EXTRACT)
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas José de San Martín
Functional Constipation, Irritable Bowel Syndrome
Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease
The purpose of this project is to study the the efficacy and safety of probiotics implantation through infusion during colonoscopy in the treatment of functional constipation and irritable bowel syndrome.
- Conditions
- Functional Constipation, Irritable Bowel Syndrome, Probiotics, Colonoscopy
- Trial name
- CPIFGD (NCT05366335)
- Testing
- Live Combined Bifidobacterium and Lactobacillus, Normal saline, Basic treatment
- Where
- China
- Volunteers
- 160 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Irritable Bowel Syndrome
Comparing the Effectiveness of 2 Diets for Patients With Irritable Bowel Syndrome
The purpose of the study is to find out if the diets often recommended for patients with Irritable Bowel Syndrome with diarrhea (IBS-D) provide adequate relief.
- Trial name
- NCT01624610
- Testing
- Dietary intervention
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Non-celiac Gluten Sensitivity, Irritable Bowel Syndrome
Identification of Gluten Sensitivity in Irritable Bowel Syndrome
The aim of our study will be to establish in how many subjects with gastrointestinal symptoms and previous diagnosis of irritable bowel syndrome (IBS), the clinical picture is attributable to non celiac gluten sensitivity (NCGS)…
- Trial name
- IBS-NCGS (NCT04017585)
- Testing
- diet containing gluten
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Bari
Irritable Bowel Syndrome, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation for Irritable Bowel Syndrome Associated Food Intolerance
Previous studies have shown that stool transplantation (FMT) have positive effect in symptoms for some patients with irritable bowel syndrome (IBS).
- Trial name
- FinFMT-IBS (NCT05361785)
- Testing
- FMT
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- Helsinki University Central Hospital
Irritable Bowel Syndrome, Digestive System Diseases
Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome
The Canadian College of Naturopathic Medicine is conducting a research study on Irritable Bowel Syndrome (IBS), a common condition in North America.
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Colonic Diseases, Functional, Colitis, Mucous
- Trial name
- IBS (NCT01887834)
- Testing
- Kyodophilus multi-strain probiotic capsules
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome Survey in Gastroenterological Adult Outpatients in China
The primary objective of this study is to estimate the overall prevalence of IBS medically diagnosed and diagnosed using Rome III or IV criteria in GI adult outpatients in China.
- Trial name
- IRONS (NCT02955316)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2, End Stage Renal Disease
Drug Interaction Potential of Pro-Inflammatory Conditions
Pro-inflammatory cytokines, which are elevated in pro-inflammatory disease states (e.g., type II diabetes mellitus [T2DM], irritable bowel diseases [IBD], and end stage renal disease [ESRD]) have been shown to inhibit hepatic…
- Conditions
- Diabetes Mellitus, Type 2, End Stage Renal Disease, Irritable Bowel Syndrome
- Trial name
- DIPPIC (NCT07360938)
- Testing
- None (Observational)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Irritable Bowel Syndrome
Treatment of Irritable Bowel Syndrome (IBS) With Sacral Nerve Stimulation
Sacral nerve stimulation (SNS) has become a well-established treatment for patients with fecal incontinence since 1995. The mechanism of action of SNS is still not fully understood but recent studies have shown that the motility…
- Trial name
- NCT00919672
- Testing
- Sacral nerve stimulation
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Colon, Irritable
Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI
The challenge is to understand how fibre interacts with whole-gut function to alter colonic fermentation of fermentable oligo-di- and mono-saccharides and polyhydric alcohols (FODMAPs).
- Trial name
- RUFUS (NCT06291272)
- Testing
- Psyllium, Methylcellulose, Inulin
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome, Lactose Intolerance
The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION)
Irritable bowel syndrome (IBS) is a functional gastrointestinal disease. There is no well-defined pharmacological treatment. This clinical trial is a prospective, double-blind, two-armed randomized controlled, single-center…
- Conditions
- Irritable Bowel Syndrome, Lactose Intolerance, Lactose Malabsorption
- Trial name
- LION (NCT05100719)
- Testing
- alverine-citrate + simethicone and lactase
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- University of Pecs
Disorders of Gut-brain Interaction, Inflammatory Bowel Disease (IBD)
A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized Patients
The purpose of the study is to compare the effectiveness of recorded gut-directed hypnosis to an educational recording in people with chronic problems in their gastrointestinal (GI) system.
- Conditions
- Disorders of Gut-brain Interaction, Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome, Abdominal Pain
- Trial name
- NCT07676136
- Testing
- Gut directed hypnotherapy via telephone intervention, Educational recording
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Stanford University
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