Clinical trials: Intubation Conditions
Ventilation, Intubation Complication
Quality of Ventilation With Facial Versus Nasal Mask vs Nasal Mask Anesthesia in Children 3 to 12 Years Old
In this single-blind clinical trial study, 70children who are candidates for lower abdominal elective surgery under general anesthesia presented at Imam Hossein Hospital in Isfahan will be included in the study and will be…
- Conditions
- Ventilation, Intubation Complication, Intubation; Difficult or Failed
- Trial name
- NCT05018468
- Testing
- Ventilation
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Critical Illness
Assessment of Hemodynamic Responses at Adequate Depth of Anesthesia Using Bispectral Index During Rapid Sequence Intubation in the Emergency Department
Rapid sequence intubation (RSI) is the standard approach for emergency airway management in critically ill patients requiring endotracheal intubation.
- Trial name
- NCT07722897
- Testing
- Bispectral Index (BIS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Akdeniz University Hospital
Apnea, Anesthesia
Functional Residual Capacity Under Apnoeic Oxygenation with Different Flow Rates in Children
During induction of general anaesthesia physiological breathing stops and needs to be artificially established with facemask ventilation, and finally tracheal intubation or placement of a supraglottic airway.
- Conditions
- Apnea, Anesthesia, Intubation Complication, Children, Only
- Trial name
- FUTURE (NCT05672329)
- Testing
- 0.2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 4 L/kg/min, FiO2 1.0 + continuous jaw thrust
- Where
- Switzerland
- Volunteers
- 108 people
- Sponsor
- Thomas Riva
Intubation Complication, Stroke, Ischemic
Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning
Adults who are unconscious or severely ill and need a breathing tube connected to a ventilator are at high risk of developing a lung infection (pneumonia) within the first few days in the intensive care unit.
- Conditions
- Intubation Complication, Stroke, Ischemic, Stroke Hemorrhagic, Head Trauma
- Trial name
- PIRAMIDES (NCT06113939)
- Testing
- airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital San Carlos, Madrid
Dyspnea, Respiratory Rate
Evaluating the Effectiveness of Incentive Spirometry
Post-operative pulmonary complications (PPCs) have a major impact on patients and healthcare expenses. The goal of perioperative respiratory therapy is to improve airway clearance, increase lung volume, and mitigate atelectasis.
- Conditions
- Dyspnea, Respiratory Rate, Oxygen Saturation, Oxygen Requirements
- Trial name
- NCT02952027
- Testing
- Use-recording, patient-reminder alarm for incentive spirometry
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Lifespan
Pediatric Endotracheal Intubation (no Specific Condition)
Ultrasound Confirmation of Endotracheal Tube Location Using a Saline Filled Cuff
The purpose of this research study is to help determine if the cuff of an endotracheal tube ( ETT) ( also known as a breathing tube)can be seen by ultrasound and to determine if visualization of this tube corresponds with correct…
- Trial name
- ET_Tube (NCT02131974)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- The University of Texas Health Science Center, Houston
Intubation, Intratracheal, Obesity
Verification of Endotracheal Tube Placement by Ultrasound in the Obese Patient
The purpose of this study is to determine whether verification of correct tube placement after endotracheal intubation in the obese patient can be conducted as fast with ultrasound as with the conventional method of combined…
- Trial name
- NCT01227486
- Testing
- Ultrasound
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Bispebjerg Hospital
Ventilation
Bag-Valve-Guedel Adaptor Vs Common Face Mask for the Ventilation of Anesthetized Bearded Men
Ventilation of a bearded patient with the commonly used face mask has low efficiency because of difficulties to achieve a tight seal around the mouth and nose.
- Trial name
- BVGA02 (NCT04376918)
- Testing
- Begin with BVGA, Begin with Face-mask
- Where
- Israel
- Volunteers
- 101 people
- Sponsor
- Hebrew University of Jerusalem
Respiratory Failure, Acute Respiratory Failure Requiring Intubation
Intra-operative Inspiratory Oxygen Fraction and Postoperative Respiratory Complications
Respiratory complications represent the second most frequent type of postoperative complications with an incidence estimated to range from 2.0% to 7.9% It has been shown that intra-operative protective ventilation is associated…
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Intubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02399878
- Testing
- Inspiratory oxygen
- Volunteers
- 70,000 people
- Sponsor
- Massachusetts General Hospital
Hoarseness of Voice, Sore-throat
A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for Intubation
The aim of this study is to compare the incidence of postoperative sore throat after intubation with two different types of laryngoscopes.
- Trial name
- NCT05531617
- Testing
- Intubation
- Where
- India
- Volunteers
- 54 people
- Sponsor
- Seth Gordhandas Sunderdas Medical College
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Intubation Complication, Critically Ill
Effect of Endotracheal Tube Plus STYLET Versus Endotracheal Tube Alone
Patients admitted to Intensive Care Units (ICU) often require respiratory support. Orotracheal intubation is one of the most frequent procedures performed in ICU.When performed in emergency settings, intubation is a challenging…
- Trial name
- STYLETO (NCT04079387)
- Testing
- ENDOTRACHEAL TUBE + STYLET, ENDOTRACHEAL TUBE ALONE
- Where
- France
- Volunteers
- 1,040 people
- Sponsor
- University Hospital, Montpellier
Rapid Sequence Intubation
Rapid Sequence Intubation and Hemodynamic Disorders in the Operating Room: a Prospective Multicenter Observational Study
There is a great heterogeneity in the practice of rapid sequence induction in the operating room in the world. There are no recent data assessing the rate of implementation of the latest French formalized expert recommendations…
- Trial name
- CoC (NCT06194058)
- Testing
- rapid sequence anesthetic induction
- Where
- 42 sites in France
- Volunteers
- 1,150 people
- Sponsor
- Nantes University Hospital
Awareness, Mechanical Ventilation
The ED-AWARENESS-2 Trial
The investigators will screen all mechanically ventilated ED patients for study eligibility and will enroll all consecutive patients satisfying inclusion and exclusion criteria.
- Conditions
- Awareness, Mechanical Ventilation, Intubation Complication, PTSD
- Trial name
- ED-AWARENES II (NCT05534243)
- Testing
- Standard neuromuscular blocker practices, Education
- Where
- 4 sites in United States
- Volunteers
- 3,212 people
- Sponsor
- Washington University School of Medicine
Coronavirus Infection, Ventilatory Failure
To Compare Videolaryngoscope Against Direct Laryngoscope for Intubation When Powered Air Purifying Respirator is Worn
Various guidelines for endotracheal intubation (insertion of breathing tube for mechanical ventilation) of Coronavirus Disease 2019 (COVID-19) patients recommend the use of videolaryngoscope (medical device used for intubation…
- Conditions
- Coronavirus Infection, Ventilatory Failure, Anesthesia Intubation Complication
- Trial name
- NCT04424953
- Testing
- McGrath videolaryngoscope, Direct laryngoscope
- Where
- Singapore
- Volunteers
- 28 people
- Sponsor
- Singapore General Hospital
Obesity, Morbid, Intubation Complication
A Comparison of Vie-Scope and Macintosh Blade Laryngoscopes in Morbidly Obese.
Macintosh laryngoscope is still considered a standard for tracheal intubation, however, visualization of the glottis may be inadequate mainly in morbidly obese patients.
- Trial name
- NCT05502120
- Testing
- Laryngoscopy with Vie-Scope laryngoscope, Laryngoscopy with Macintosh blade laryngoscope
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lodz
Gagging
Glossopharyngeal Nerve Blockade for Awake Videolaryngoscope Assisted Endotracheal Intubation in the Morbidly Obese
The investigators wish to determine if application of 2% lidocaine soaked gauze to the peritonsillar pillars will decrease the amount of gagging caused by awake videolaryngocope assisted tracheal intubation in the morbidly obese.
- Trial name
- NCT01791439
- Testing
- lidocaine
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Royal Victoria Hospital, Canada
Newborn Morbidity, Pain
Epidemiology of Painful Procedures in Neonates
Sick or premature neonates are exposed to frequent painful and stressful procedures during their stay in neonatal intensive care units.
- Conditions
- Newborn Morbidity, Pain, Procedures, Intratracheal Intubation
- Trial name
- EPIPPAIN (NCT01346813)
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hôpital Armand Trousseau
Neuromuscular Blockade, Critical Illness
Pharmacological Reversal of Neuromuscular Blockade in Critically Ill Patients
The goal of this clinical trial is to compare the effect of use of reversal agents for neuromuscular blockade in critically ill patients on time for neurological assessment after endotracheal intubation The main questions it aims…
- Conditions
- Neuromuscular Blockade, Critical Illness, Neurologic Findings
- Trial name
- NCT05993390
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Obesity Female Patients Require General Anaesthesia With Intubation and Atracurium Curarization
Intubation Conditions With Atracurium After Three Minutes
The purpose of this study is to evaluate intubation conditions with the use of atracurium after a fixed three-minute delay
- Trial name
- CINTROI (NCT04808440)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris