Clinical trials: Intubation Complication, active
Intubation Skill, Intubation Complications
Establish Whether Hyperangulated Videolaryngoscopy (HAVL) Can be Used to Facilitate Tracheal Intubation Effectively and Safely in Unselected Adult Patients; Describe the Population in Whom HAVL Fails to Facilitate Tracheal Intubation Successfully, Identifying Any Contributory Characteristics.
When patients have a general anaesthetic (go to sleep for surgery), the anaesthetist often places a small tube into their windpipe (intubation) to help them breathe.
- Conditions
- Intubation Skill, Intubation Complications, Intubation With Uncuffed Endotracheal Tube
- Trial name
- NCT07600502
- Testing
- Hyperangulated videolaryngoscopy
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Intubation Complication
Comparison of First Attempt Success Based on Endotracheal Tube Type During Videolaryngoscope-guided Intubation Without Stylet
Patients are randomly assigned to either the oral RAE tube group (Group O) or the reinforced tube group (Group R). In both groups, tracheal intubation is performed using a videolaryngoscope without a stylet, and the first-attempt…
- Trial name
- NCT07682480
- Testing
- endotracheal tube
- Volunteers
- 246 people
- Sponsor
- Seoul National University Hospital
Delayed Sequence Intubation, Rapid Sequence Induction and Intubation
Comparison of Peri-intubation Oxygenation Values and Complications in Patients Intubated With the Delayed Versus Rapid Sequence Intubation Protocols
This study compares two different methods of helping patients breathe by placing a tube in their airway (intubation) in an emergency setting.
- Conditions
- Delayed Sequence Intubation, Rapid Sequence Induction and Intubation, Intubation, Intubation Complications
- Trial name
- DSI vs RSI (NCT07380763)
- Testing
- Delayed Sequence Intubation, Rapid Sequence Intubation
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Intubation, Intubation Complications
A Stepped Wedge Cluster Randomised Trial Of Video Versus Direct Laryngoscopy For Intubation Of Newborn Infants
Many newborn babies have difficulty breathing. When babies need a lot of help, a doctor will intubate them - i.e. put a tube into their windpipe (trachea) - so that they can be given support with a breathing machine.
- Conditions
- Intubation, Intubation Complications, Infant, Newborn, Infant Respiratory Distress Syndrome
- Trial name
- NEU-VODE (NCT06757543)
- Testing
- Video laryngoscopy, Direct laryngoscopy with standard laryngoscope
- Where
- 17 sites in Croatia, Czechia and 8 more
- Volunteers
- 840 people
- Sponsor
- University College Dublin
Anesthesia, Intubation; Difficult or Failed
PrediSuisse: Automatized Assessment of Difficult Airway
In the "PrediSuisse" research project, the investigators aim to create a reliable, reproducible, ultra-portable and radiation-free automatized software, able to identify automatically collected features, facial characteristics…
- Conditions
- Anesthesia, Intubation; Difficult or Failed, Airway Complication of Anesthesia
- Trial name
- PrediSuisse (NCT06453525)
- Testing
- intubation
- Where
- Switzerland
- Volunteers
- 1,800 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Intubation Complication
Comparison of First Attempt Success in Nasotracheal Intubation Using Macintosh Videolaryngoscope vs. Flexible Bronchoscope
Participants are randomly assigned to two groups: one group undergoes nasotracheal intubation using a videolaryngoscope, while the other group undergoes nasotracheal intubation using a flexible bronchoscope.
- Trial name
- NCT06964295
- Testing
- Macintosh videolaryngoscope, Flexible bronchoscope
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Seoul National University Hospital
Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal)
Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study
The goal of this observational study is to evaluate different methods of surfactant administration in preterm infants with respiratory distress syndrome (RDS).
- Conditions
- Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal), Respiratory Distress Syndrome (RDS), Respiratory Distress Syndrome of Newborn
- Trial name
- NCT07550218
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Airway Management, Intubation; Difficult or Failed
Data-driven Development of a Core Dataset for Difficult Airway Alerts
Previous difficult airway management is the most accurate predictor of future difficulty. Consistent documentation is paramount for future airway planning, but requires reliable, reproducible and easily accessible information.
- Conditions
- Airway Management, Intubation; Difficult or Failed, Airway Complication of Anesthesia
- Trial name
- FingAIRprint (NCT07275567)
- Where
- Germany
- Volunteers
- 1,785 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Sore Throat, Hoarseness
A Randomized, Comparative, Controlled Study of Differences in the Incidence of Postoperative Sore Throat (POST) by Inner Diameter Size of the TaperGuardTM Endotracheal Tube (ETT)
Postoperative sore throat (POST) is a common complication following general anesthesia involving endotracheal intubation, often leading to decreased patient satisfaction.
- Trial name
- NCT07511998
- Testing
- TaperGuard™ Endotracheal Tube
- Where
- South Korea
- Volunteers
- 246 people
- Sponsor
- Kyungpook National University Chilgok Hospital
Intubation Complication
Incidence of Acute Laryngeal Injury Following Endotracheal Intubation
The purpose of this investigation is to delineate the incidence of acute and chronic laryngeal injury following intubation within our health system.
- Trial name
- NCT03250975
- Testing
- Budesonide and Azithromycin
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Vanderbilt University Medical Center
Awareness, Mechanical Ventilation
The ED-AWARENESS-2 Trial
The investigators will screen all mechanically ventilated ED patients for study eligibility and will enroll all consecutive patients satisfying inclusion and exclusion criteria.
- Conditions
- Awareness, Mechanical Ventilation, Intubation Complication, PTSD
- Trial name
- ED-AWARENES II (NCT05534243)
- Testing
- Standard neuromuscular blocker practices, Education
- Where
- 4 sites in United States
- Volunteers
- 3,212 people
- Sponsor
- Washington University School of Medicine
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Intubation Complication
Neurologic Function Post Intubation
The frequency of oxygen desaturation during emergency intubation is not uncommon. However, the significance and clinical sequalae of hypoxia during emergency intubation in critically ill, non-trauma patients is not known.
- Trial name
- NeuroHypoxia (NCT05412823)
- Where
- Saudi Arabia
- Volunteers
- 1,000 people
- Sponsor
- King Abdulaziz University
Intubation Complication, Eschar
Clinical and Economic Comparison of 2 Methods of Intubation Tube Fixation : AnchorFastTM Versus Current Cord Fixation
The aim of this study is to assess the benefits of using the Anchorfast device in reducing complications associated with intubation tube fixation, in terms of the rate of pressure ulcer development, the rate of intubation tube…
- Trial name
- AnchorDon (NCT06533436)
- Testing
- Corded tube care, Tube care attached by AnchorFast, Caregiver's evaluation on each tube fixation
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Hopital Foch
Correlation of Difficult Airway Markers With Ultrasonographic Measurements in Obese Patients
Comparison of Airway Ultrasonography and Laryngoscopy Methods in Obese Patients
The main objective of this study was to examine the relationship between classical markers used in assessing difficult airway management in obese patients (Mallampati score, thyromental distance, sternomental distance, neck…
- Trial name
- NCT07482436
- Testing
- Airway ultrasonography, Macintosh Laryngoscope Intubation, Tuoren Videolaryngoscope Intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
One Lung Ventilation, Intubation Complication
Videolaryngoscopy vs Direct Laryngoscopy for Double Lumen Tube Lumen Tube Placement - A Multicentre Randomized-controlled Trial (VOLCANO Study)
The general aim of the study is to observe whether the use of the Mc Grath™ videolaryngoscope instead of direct laryngoscopy can represent, as in the case of the single-lumen tube, an added value in the placement of the…
- Trial name
- VOLCANO (NCT06466759)
- Testing
- Mc Grath Videolaryngoscope
- Volunteers
- 750 people
- Sponsor
- Luca Brazzi
Critical Illness, Difficult; Intubation, Postpartum, During Puerperium
Ultrasound Airway Assessment of Critically Ill Preeclamptic; Comparison Between Two Technique
Unexpected difficult airway exposes the patient to serious morbidity and even mortality. The changes in pregnancy and preeclampsia increase the risk of difficult intubation.
- Conditions
- Critical Illness, Difficult; Intubation, Postpartum, During Puerperium, Pre-Eclampsia
- Trial name
- NCT06651879
- Testing
- techniques of ultrasound examination of the airway
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Respiratory Distress Syndrome in Premature Infant
Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam
Preterm babies often have trouble breathing because their lungs are not fully developed. This condition is called respiratory distress syndrome (RDS). A medicine called surfactant helps their lungs open up and work better.
- Trial name
- NEOSURF (NCT07098910)
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways (SALSA), Intubation - Surfactant administration - Extubation (INSURE)
- Where
- Vietnam
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Nosocomial Infection, Nosocomial Pneumonia
Mechanical Insufflation-exsufflation and Hypertonic Saline in Nosocomial Bacterial Respiratory Tract Infection
Multicenter, randomized open label clinical trial to evaluate IEM and HS as concomitant therapy for respiratory tract infection in patients under artificial ventilation in the ICU.
- Conditions
- Nosocomial Infection, Nosocomial Pneumonia, Tracheobronchitis, Mechanical Ventilation Complication
- Trial name
- ABSENTA (NCT06310941)
- Testing
- Mechanical insufflation-exsufflation, Standard of Care, Hypertonic saline with hyaluronic acid
- Where
- 8 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital San Carlos, Madrid
Rapide Sequence Induction, Tracheal Intubation
Pain Assessment During Rapid Sequence Induction
Rapid sequence induction (RSI) is a standard anesthesia technique used in patients at risk of aspiration. Although tracheal intubation following RSI is a frequent and painful procedure, no study has yet evaluated nociception…
- Conditions
- Rapide Sequence Induction, Tracheal Intubation, Nociception, General Anesthesia
- Trial name
- NARSI (NCT07588165)
- Testing
- No Intervention: Observational Cohort
- Where
- Monaco
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Princesse Grace