Clinical trials: Intravascular Ultrasound
Coronary Artery Disease, Hypertension
Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound
The purpose of this study is to evaluate the effect of intensive blood pressure control compared to standard blood pressure control on progression of coronary atherosclerosis by intravascular ultrasound in hypertensive patients…
- Trial name
- PREVUS (NCT01230216)
- Testing
- control systolic blood pressure less than 120 mmHg, control systolic blood pressure less than 140 mmHg
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Takeshi Morimoto
Positive-Pressure Respirations, Respiratory Failure
Inferior Vena Cava Indexes in Positive Pressure Supports
Collapsibility (CI-IVC), distensibility (dIVC) and delta (ΔIVC) indices, which are dynamic measures of inferior vena cava (IVC) diameter, are used to assess the intravascular volume status in critically ill patients.
- Trial name
- NCT03452046
- Testing
- IVC diametres
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Tepecik Training and Research Hospital
Caudal Epidural Block
Comparison of Tuohy Needle and Quincke Needle During Caudal Epidural Injection
Park et al. reported the results of a randomized study of the use of ultrasound and the use of C-arm in caudal epidural block. However, it is difficult to determine the overall epidural space contrast agent spread with ultrasound…
- Trial name
- NCT05504590
- Testing
- Tuohy needle group, Quincke needle group
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Gangnam Severance Hospital
Coronary Artery Stenosis
Fractional Flow Reserve and Intravascular Ultrasound in Evaluating Intermediate Coronary Lesions
Recent studies have shown that optimal IVUS criteria defining the functional significance (FFR < 0.8) of intermediate coronary stenoses is different according to their locations of the coronary tree.
- Trial name
- NCT01414361
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Hospital
Coronary Vessel, Coronary Circulation
Vascular Effects of Alirocumab in Acute MI-Patients
Coronary artery disease (CAD) is the most frequent cause of mortality in the industrialized world. Hypercholesterolemia is a major risk factor for the development and progression of CAD.
- Conditions
- Coronary Vessel, Coronary Circulation, Atheroma; Myocardial
- Trial name
- PACMAN-AMI (NCT03067844)
- Testing
- Alirocumab
- Where
- 9 sites in Austria, Denmark and 2 more
- Volunteers
- 294 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Disease, Left Main Coronary Artery Disease
IVUS VS CAG Guided PCI for Patients With LMB Lesion
To compare the 3 - year clinical follow - up results of patients with left main bifurcation lesions treated by intravascular ultrasound(IVUS) - guided and coronary angiography(CAG) - guided percutaneous coronary…
- Trial name
- Infinite (NCT04072003)
- Testing
- intravascular ultrasound (IVUS), coronary angiography
- Volunteers
- 616 people
- Sponsor
- Shanghai Zhongshan Hospital
Plaque
Adverse Plaque Characteristics in CCTA and TVC Imaging
The present study is intended to assess the vulnerability of plaques seen on CCTA by means of TVC Imaging System and to make comparisons between plaques with adverse plaque characteristics and ones without adverse plaque…
- Trial name
- CITRUS (NCT02350959)
- Testing
- Atorvastatin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- National Health Insurance Service Ilsan Hospital
Femoral Artery Stenosis, Angioplasty
an Observational Study Evaluting the Effectiveness and Safety of DKutting LL Noval Scoring Balloon Angioplasty for Vessel Preparation Facilitated by IVUS on the Lower Limb Ischemia Patients With Calcified Lesions
This is a prospective, single-center, single-arm, observational study. It plans to enroll 58 patients with moderate to severely calcified lesions in the femoropopliteal or infrapopliteal arteries.
- Conditions
- Femoral Artery Stenosis, Angioplasty, Cutting Balloon Angioplasty, Calcifications, Vascular
- Trial name
- DkuLL CALVEP (NCT07397390)
- Testing
- DKutting LL scoring balloon angioplasty
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Coronary Artery Disease, Myocardial Infarction
Optical Coherence Tomography Guided Percutaneous Coronary Intervention With Stent Implantation
Coronary artery disease is one of the most prevalent diseases in the western countries. A waxy substance called plaque can build up inside the coronary arteries.
- Trial name
- OCTACS (NCT02272283)
- Testing
- Percutaneous coronary intervention with Nobori biolimus-eluting stent implantation
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Hypotension, Sepsis
Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status
Ultrasound represents an attractive non-invasive method to assess hemodynamic status. Understanding dynamic changes in hemodynamics in situations such as hypovolemia, sepsis, and cardiogenic shock can potentially help improve…
- Trial name
- NCT02907931
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Coronary Artery Disease (CAD), Calcific Coronary Arteriosclerosis
Overviewing Real-World Outcomes to Boost Interventional Management of CAlcified Coronary Lesions: the OROBICA Registry.
The OROBICA (Overviewing Real-World Outcomes to Boost Interventional Management of CAlcified Coronary Lesions) Registry is a multicenter, ambispective, real-world observational study designed to evaluate clinical, procedural…
- Conditions
- Coronary Artery Disease (CAD), Calcific Coronary Arteriosclerosis, Intravascular Lithotripsy; Rotational Atherectomy; OFDI, Orbital Atherectomy
- Trial name
- OROBICA (NCT07566403)
- Testing
- Percutaneous coronary intervention with or without stent implantation
- Where
- Italy
- Volunteers
- 3,000 people
- Sponsor
- Papa Giovanni XXIII Hospital
Atherosclerosis, Coronary Artery Disease
Study of Near Infrared Spectroscopy (NIRS) and Intravascular Ultrasound (IVUS) Combination Coronary Catheter
This study is designed to evaluate the technical performance and clinical handling of a coronary catheter that includes two imaging techniques.
- Conditions
- Atherosclerosis, Coronary Artery Disease, Myocardial Ischemia, Myocardial Infarction
- Trial name
- SAVOIR (NCT00901446)
- Testing
- Intravascular ultrasound and spectroscopy
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Infraredx
Iliac Vein Compression Syndrome
Comparison of Intravascular Ultrasound With Venography in the Diagnosis and Treatment of Iliac Vein Compression Syndrome
The aim of this study is to compare intravascular ultrasound with venography in the diagnosis and treatment of iliac vein compression syndrome.
- Trial name
- NCT03309969
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Zhongshan Hospital
Atherosclerosis
Rosiglitazone Versus a Sulfonylurea On Progression Of Atherosclerosis In Patients With Heart Disease And Type 2 Diabetes
The purpose of this study is to test the safety and effectiveness of rosiglitazone against a sulfonylurea in reducing or slowing the development of atherosclerosis in the blood vessels of the heart.
- Trial name
- NCT00116831
- Testing
- Glipizide, rosiglitazone maleate
- Where
- 156 sites in United States, Argentina and 18 more
- Volunteers
- 672 people
- Sponsor
- GlaxoSmithKline
Coronary Artery Disease
Vascular Evaluation for Revascularization: Defining the Indications for Coronary Therapy: A Pilot Study
The present prospective, multicenter study will therefore be performed with the primary objective of establishing the correlation between fractional flow reserve (FFR) and intravascular ultrasound with virtual histology…
- Trial name
- VERDICT (NCT01158053)
- Testing
- FFR and VH-IVUS, IVUS and FFR
- Volunteers
- 291 people
- Sponsor
- Volcano Corporation
Coronary Artery Disease
Comparison Between OFDI and IVUS in PCI Guidance for Biolimus A9 Eluting Stent Implantation
The aim of this study is to assess clinical safety and efficacy of percutaneous coronary intervention (PCI) using a newer generation drug-eluting stent (DES) in the context of optical frequency domain imaging (OFDI) guidance or…
- Trial name
- MISTIC-1 (NCT03292081)
- Testing
- OFDI, IVUS
- Where
- Japan
- Volunteers
- 96 people
- Sponsor
- Fujita Health University
Coronary Artery Disease
OPtical Frequency Domain Imaging Versus INtravascular Ultrasound in Percutaneous Coronary InterventiON - OPINION Imaging
This study is the sub-study of OPINION Trial. (UMIN000010580) The aim of this study is to evaluate how Optical frequency domain imaging (OFDI) or Intravascular Ultrasound (IVUS) imaging technology influence to the Percutaneous…
- Trial name
- NCT01873222
- Testing
- OFDI-guided PCI & IVUS, IVUS-guided PCI & OFDI
- Where
- Japan
- Volunteers
- 106 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Coronary Artery Disease, Aortic Valve Disease
Deploying Novel Imaging Modalities Towards a Three-dimensional (3D) CARDIOvascular PATHology
The goal of the 3D-CARDIOPATH study is to investigate the potential added value of emerging 3D imaging modalities by imaging ex vivo cardiac specimens (diseased coronary arteries, calcific aortic valves, and thrombotic materials)…
- Conditions
- Coronary Artery Disease, Aortic Valve Disease, Aortic Valve Calcification, STEMI
- Trial name
- 3D-CARDIOPATH (NCT05975567)
- Testing
- Three-dimensional imaging of the collected cardiac specimens
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Venous Insufficiency, Chronic Venous Thrombosis
Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease
Chronic obstruction of the iliac veins or inferior vena cava can occur as a result of deep vein thrombosis (DVT), or due to extrinsic compression in non-thrombotic iliac vein lesions (NIVLs).
- Conditions
- Chronic Venous Insufficiency, Chronic Venous Thrombosis, Iliac Vein Stenosis, Iliac Vein Obstruction
- Trial name
- BEST (NCT05622500)
- Testing
- Deep venous stenting, Best medical therapy
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Chronic Limb-Threatening Ischemia
IVUS Guidance in BTK Interventions
Chronic limb-threatening ischemia (CLTI) is a severe form of peripheral artery disease in which very poor blood flow in the arteries below the knee can cause rest pain, non-healing wounds, and even loss of the limb.
- Trial name
- IMAGE-BTK (NCT07731997)
- Testing
- Intravascular ultrasound-guided EVT, Angiography-guided EVT
- Where
- 4 sites in Taiwan
- Volunteers
- 212 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital