Clinical trials: Intratracheal Intubation
Lidocaine
Lidocaine in the Prevention of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation
Direct laryngoscopy and endotracheal intubation procedure stimulate the sympathetic nervous system, causing catecholamine release into the circulation and consequently hemodynamic changes.There are many studies showing that…
- Trial name
- NCT06107543
- Testing
- Nebulized Lidocaine, Iv Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Paediatric Airway Management
Improvement of Laryngoscopic View by Bed-up-head-elevated Position During Tracheal Intubation in Paediatric Patients
The goal of this prospective observational study is to learn about improvement of laryngoscopic view by Bed-Up-Head-Elevated (BUHE) during tracheal intubation in paediatric patients. The main question it aims to answer is: 1.
- Trial name
- NCT05885789
- Testing
- Intubation in Bed-Up-Head-Elevated (BUHE) position
- Where
- Malaysia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Airway Management, Tracheal Intubation
Taiwan ED Airway Quality Surveillance Registry (TEAR)
This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan.
- Conditions
- Airway Management, Tracheal Intubation, Emergency Department, Peri-intubation Adverse Events
- Trial name
- NCT07574450
- Where
- Taiwan
- Volunteers
- 1,200 people
- Sponsor
- Chang Gung Memorial Hospital
Muscle Relaxation, Intubation Complication
Endotracheal Intubation Without Muscle Relaxants
Prospective study conducted between March 2013 and November 2014 at Hospital Universitario Puerta de Hierro-Majadahonda, in Madrid, Spain to identify complications and evaluate the efficacy of pure inhalational anesthesia…
- Trial name
- NCT03112564
- Testing
- Avoidance of rocuronium/cisatracurium, Sevoflurane 8% + Intravenous fentanyl
- Where
- Spain
- Volunteers
- 91 people
- Sponsor
- Puerta de Hierro University Hospital
Newborn, Preterm
Influence of Premedication Protocols for Neonatal Endotracheal Intubation on Cerebral Oxygenation
The purpose of this study is to examine the influence of premedication drugs Atropin, Fentanyl and Mivacurium and of endotracheal intubation on cerebral oxygenation and cardiac output in term and preterm newborn infants.
- Conditions
- Newborn, Preterm, Intubation
- Trial name
- NCT01427985
- Testing
- Atropine, Fentanyl, Mivacurium
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University of Ulm
Gastroesophageal Reflux in Laparoscopy
Risks of Gastroesophageal Reflux in the Endotracheal Intubation or the I-gel
In the use of the second supraglottic airway device- i-gel in the laparoscopic pneumoperitoneum and Trendelenburg (LPT) surgical positioning, our data reported that the leak fraction in the i-gel group was higher than in the…
- Trial name
- NCT03634449
- Testing
- i-gel, endotracheal tube
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Mechanical Ventilation Complication, Tracheal Intubation Morbidity
Continuous Endotracheal Cuff Pressure Control to Prevent Ventilator Associated Respiratory Infections
The purpose of the study is to determine whether automated cuff pressure control results in a reduction in the proportion of patients developing ventilator associated respiratory infections during their stay in intensive care.
- Conditions
- Mechanical Ventilation Complication, Tracheal Intubation Morbidity, Ventilator-Associated Pneumonia, Hospital Acquired Infection
- Trial name
- VARI-prevent (NCT02966392)
- Testing
- Tracoe cuff pressure controller
- Where
- 3 sites in Vietnam
- Volunteers
- 600 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Endotracheal Intubation
Endotracheal Intubation in Prehospital Scenario
We therefore designed this randomized crossover study to compare C-MAC with Macintosh laryngoscope in emergency intubation performed by paramedics according to three different intubator positions.
- Trial name
- NCT02681835
- Testing
- C-MAC laryngoscope, Macintosh laryngoscope
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Acute Hypoxemic Respiratory Failure
Comparison Physiological Effects According to Preoxygenation Method Using EIT
Hypoxemia during endotracheal intubation is one of this procedure's most frequent and severe complications, which can lead to cardiac arrest and other adverse outcomes.
- Trial name
- PreoxyEIT (NCT05962073)
- Testing
- HFNC
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Intubation, Intratracheal, Airway Management
Comparison Among Three Different Video Scope Guided Nasotracheal Intubation.
Nasotracheal intubation (NTI) has become the most optimal alternative to oral endotracheal intubation for oro-maxillofacial surgery because it can offer an excellent vision field of the mouth.
- Trial name
- NTI (NCT05534451)
- Testing
- video laryngoscope guided nasotracheal intubation, video rigid laryngoscope guided nasotracheal intubation, video fiberoptic scope guided nasotracheal intubation
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Intubation Complication, Adverse Events
CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation
The investigators' overall objective is to assess the incidence of critical events related to tracheal intubation at all international study sites.
- Trial name
- CRICKET (NCT05804188)
- Testing
- tracheal intubation
- Where
- 8 sites in United States, Australia and 3 more
- Volunteers
- 105,000 people
- Sponsor
- Thomas Riva
Intubation Complication
POCUS ASSESSMENT FOR TRACHEAL VS OESOPHAGEAL INTUBATION
The clinical importance of airway management has gained prominence in the last decade in most scientific societies with the aim of improving the standard of care.
- Trial name
- PATO (NCT05983666)
- Testing
- Ultrasound Oesophageal Intubation
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Airway Management, Intubation, Endotracheal
Two Video Laryngoscopes (Laringocel® and C-MAC®) for First-Attempt Intubation in Adults Undergoing Elective Surgery
This study will test two video laryngoscopes that help doctors place a breathing tube during surgery. A breathing tube is needed for people who receive general anesthesia so they can breathe safely.
- Trial name
- LARINGOCOL (NCT07239141)
- Testing
- Laringocel® videolaryngoscope, C-MAC® D-Blade videolaryngoscope
- Where
- Colombia
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Mario Zamudio
Postsynaptic Potential Summation
Neurophysiological Monitoring and Videolaryngoscopy
Myopathic patients undergoing cervical spine surgery are at risk for postoperative neurological deficits and sequelae. Awake fiberoptic intubation is considered the technique of choice for tracheal intubation in patient with…
- Trial name
- NCT04576637
- Testing
- Neurophysiological monitoring during intubation
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rabin Medical Center
Airway Management, Intubation, Intratracheal
Place of the Video-laryngoscope in Learning Intubation by Simulation
The aim of the study was to determine the impact of the videolaryngoscope on reducing the time needed to intubate on a low-fidelity manikin for beginners.
- Conditions
- Airway Management, Intubation, Intratracheal, Simulation, Laryngoscopy
- Trial name
- NCT05859542
- Testing
- Videolaryngoscope first, Direct laryngoscope first
- Where
- Tunisia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
COVID-19, Respiratory Failure
Characteristics and Outcomes of Patients With COVID-19 Treated With HFNO and Prone Positioning
A subset of patients with COVID-19 develops acute respiratory failure and acute respiratory distress syndrome (ARDS) (1). The use of invasive mechanical ventilation for the treatment of these conditions is associated with high…
- Conditions
- COVID-19, Respiratory Failure, Prone Position, Endotracheal Intubation
- Trial name
- AW-PP_Covid (NCT05178212)
- Where
- Argentina
- Volunteers
- 600 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Critically Ill Adults in the ICU, Requiring Endotracheal Intubation
Effect of a FLUid Bolus or a Low Dose VAsopressor Infusion on Cardiovascular Collapse Among Critically Ill Adults Undergoing Tracheal Intubation.
Tracheal intubation, which is one of the most commonly performed procedures in the care of critically ill patients in intensive care unit, is associated with a high incidence of complications.
- Trial name
- FLUVA (NCT05318066)
- Testing
- Ringer Lactate and Norepinephrine infusion
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Tata Memorial Centre
Oliceridine
Oliceridine Dose for Tracheal Intubation Hemodynamic Elevation: Up-and-Down Trial
This is a clinical trial using an up-and-down sequential design, aiming to investigate the median effective dose (ED50) and 95% effective dose (ED95) of oliceridine for inhibiting hyperdynamic responses induced by tracheal…
- Trial name
- NCT07154979
- Testing
- Oliceridine Injection
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Shiyou Wei
Post Operative Sore Throat
Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study
Sore throat includes specific symptoms such as dysphagia, dysphonia, hoarseness, continuous throat pain, and pharyngeal dryness.
- Trial name
- NCT05975346
- Testing
- Ketamine, saline nebulization
- Volunteers
- 80 people
- Sponsor
- Sohag University
Dysphagia, Respiratory Complications
Trial- Dysphagia From ETT or GI Endoscopy
The purpose of this study is to conduct a randomized clinical trial to compare the incidence of dysphagia in patients receiving general anesthesia with and without an endotracheal tube for Upper gastrointestinal endoscopy.
- Trial name
- NCT02460055
- Testing
- endotracheal tube, propofol, Fentanyl
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine