Airway ManagementNCT07574450
Taiwan ED Airway Quality Surveillance Registry (TEAR)
An observational study of Airway Management and Tracheal Intubation, run by Chang Gung Memorial Hospital at 1 site in Taiwan.
Trial summary
This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan. The registry focuses on process quality indicators, including first-pass success, and patient-safety outcomes, including hypoxemia, hypotension, and… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Airway Management, Tracheal Intubation, Emergency Department
- How many people
- 1,200 participants
- Where
- 1 siteTaiwan
- Study dates
- Aug 2026to Dec 2029
- How long will I take part?
- 1 Month
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Consecutive adult emergency department patients undergoing tracheal intubation at participating hospitals in Taiwan.
Who may be able to join
- Undergoing tracheal intubation in the emergency department during the study period
Who cannot join
- Prehospital intubation; intubation performed solely for elective anesthesia/procedural sedation outside emergency indications
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site
New Taipei Municipal Tucheng Hospital, New Taipei City, Taiwan
New Taipei City
TING HAO YANG, Doctor, +886978989007, mr2434@cgmh.org.tw
About this study
Official title: The Taiwan ED Airway Quality Surveillance Registry (TEAR): A Prospective Multicenter Observational Study
This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan. The registry focuses on process quality indicators, including first-pass success, and patient-safety outcomes, including hypoxemia, hypotension, and peri-intubation cardiac arrest within 30 minutes of intubation. Routinely generated laboratory and physiologic variables are also collected to improve risk stratification and identify predictors of major adverse events. The study is non-interventional and does not alter clinical care.
- Conditions
- Airway Management, Tracheal Intubation, Emergency Department, Peri-intubation Adverse Events
- Keywords
- first-pass success, hypoxemia, hypotension, cardiac arrest, registry
- Medical subject headings
- Emergencies, Hypoxia, Hypotension, Heart Arrest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Adult patients in ED require emergent tracheal intubation | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of major adverse peri-intubation events within 30 minutes after the start of intubation
severe hypoxemia, severe hypotension/cardiovascular instability, or cardiac arrest.
Measured: Periprocedural, through 30 minutes after the start of intubation
Secondary outcomes (2)
First-pass success
Measured: Periprocedural
In-hospital mortality
Measured: From intubation to hospital discharge, assessed up to 90 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 May 2026
- Study startAug 2026 (estimated)
- Primary completionJul 2029 (estimated)
- Study completionDec 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (7)Papers the sponsor has linked to this study.
- Other trials for Airway ManagementStudies of the same condition, open and under way.
- More trials run by Chang Gung Memorial HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,200 participants (estimated)
- Target duration
- 1 Month
Sponsor and investigators
- Lead sponsor
- Chang Gung Memorial Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, YANG TING HAO, Chang Gung Memorial Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07574450
- Sponsor's protocol ID
- 202501836B0
- Status last verified
- May 2026
- First submitted
- 27 Apr 2026
- Last updated
- 8 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: De-identified data will be retained under institutional governance and are not currently planned for public individual participant data sharing.
Publications
Garcia SI, Smischney NJ, Sandefur BJ, D'Andria Ursoleo J, Kelm DJ, Wieruszewski PM. Peri-intubation Cardiovascular Collapse During Emergency Airway Management. Pulm Ther. 2025 Dec;11(4):569-585. doi: 10.1007/s41030-025-00326-x. Epub 2025 Oct 16.
PubMed 41094343Hasegawa K, Hagiwara Y, Chiba T, Watase H, Walls RM, Brown DF, Brown CA 3rd; Japanese Emergency Medicine Research Alliance. Emergency airway management in Japan: Interim analysis of a multi-center prospective observational study. Resuscitation. 2012 Apr;83(4):428-33. doi: 10.1016/j.resuscitation.2011.11.027. Epub 2011 Dec 8.
PubMed 22155701Maia IWA, Besen BAMP, Silva LOJE, von Hellmann R, Hajjar LA, Sandefur BJ, Pedrollo DF, Nogueira CG, Figueiredo NMP, Miranda CH, Martins D, Baumgratz TD, Bergesch B, Costa D, Colleoni O, Zanettini J, Freitas AP, Moreira NP, Gaspar PL, Tambelli R, Costa MC, Silveira S, Correia W, de Maria RG, Filho UAV, Weber AP, da Silva Castro V, Dornelles CFD, Tabach BS, Guimaraes HP, Stanzani G, Gava TF, Mullan A, Souza HP, Ranzani OT, Bellolio F, Alencar JCG; BARCO group. Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study. Crit Care. 2025 Apr 17;29(1):155. doi: 10.1186/s13054-025-05392-w.
PubMed 40247381Cho J, Cho YS, You JS, Lee HS, Kim H, Chung HS; Korean Emergency Airway Management Society. Current status of emergency airway management for elderly patients in Korea: Multicentre study using the Korean Emergency Airway Management Registry. Emerg Med Australas. 2013 Oct;25(5):439-44. doi: 10.1111/1742-6723.12122. Epub 2013 Sep 9.
PubMed 24099373April MD, Arana A, Reynolds JC, Carlson JN, Davis WT, Schauer SG, Oliver JJ, Summers SM, Long B, Walls RM, Brown CA 3rd; NEAR Investigators. Peri-intubation cardiac arrest in the Emergency Department: A National Emergency Airway Registry (NEAR) study. Resuscitation. 2021 May;162:403-411. doi: 10.1016/j.resuscitation.2021.02.039. Epub 2021 Mar 5.
PubMed 33684505Alkhouri H, Vassiliadis J, Murray M, Mackenzie J, Tzannes A, McCarthy S, Fogg T. Emergency airway management in Australian and New Zealand emergency departments: A multicentre descriptive study of 3710 emergency intubations. Emerg Med Australas. 2017 Oct;29(5):499-508. doi: 10.1111/1742-6723.12815. Epub 2017 Jun 5.
PubMed 28582801Russotto V, Myatra SN, Laffey JG, Tassistro E, Antolini L, Bauer P, Lascarrou JB, Szuldrzynski K, Camporota L, Pelosi P, Sorbello M, Higgs A, Greif R, Putensen C, Agvald-Ohman C, Chalkias A, Bokums K, Brewster D, Rossi E, Fumagalli R, Pesenti A, Foti G, Bellani G; INTUBE Study Investigators. Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries. JAMA. 2021 Mar 23;325(12):1164-1172. doi: 10.1001/jama.2021.1727.
PubMed 33755076
Study at a glance
From the registry record, last updated by the sponsor on 8 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Taiwan ED Airway Quality Surveillance Registry (TEAR): A Prospective Multicenter Observational Study
- ClinicalTrials.gov ID
- NCT07574450
- Acronym / sponsor ID
- 202501836B0
- Conditions
- Airway Management, Tracheal Intubation, Emergency Department, Peri-intubation Adverse Events
- Keywords
- first-pass success, hypoxemia, hypotension, cardiac arrest, registry
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 1,200 participants (estimated)
- Lead sponsor
- Chang Gung Memorial HospitalUniversity, hospital or other
- Study start
- Aug 2026 (estimated)
- Primary completion
- Jul 2029 (estimated)
- Study completion
- Dec 2029 (estimated)
- First posted
- 8 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan. The registry focuses on process quality indicators, including first-pass success, and patient-safety outcomes, including hypoxemia, hypotension, and peri-intubation cardiac arrest within 30 minutes of intubation. Routinely generated laboratory and physiologic variables are also collected to improve risk stratification and identify predictors of major adverse events. The study is non-interventional and does not alter clinical care.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Month
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Adult patients in ED require emergent tracheal intubation | – | – |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Consecutive adult emergency department patients undergoing tracheal intubation at participating hospitals in Taiwan.
Key inclusion criteria (1 listed)
- Undergoing tracheal intubation in the emergency department during the study period
Key exclusion criteria (1 listed)
- Prehospital intubation; intubation performed solely for elective anesthesia/procedural sedation outside emergency indications
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Incidence of major adverse peri-intubation events within 30 minutes after the start of intubation
Time frame: Periprocedural, through 30 minutes after the start of intubation
severe hypoxemia, severe hypotension/cardiovascular instability, or cardiac arrest.
2 secondary outcomes
First-pass success
Time frame: Periprocedural
In-hospital mortality
Time frame: From intubation to hospital discharge, assessed up to 90 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 May 2026.
- Background: PubMed 41094343Garcia SI, Smischney NJ, Sandefur BJ, D'Andria Ursoleo J, Kelm DJ, Wieruszewski PM. Peri-intubation Cardiovascular Collapse During Emergency Airway Management. Pulm Ther. 2025 Dec;11(4):569-585. doi: 10.1007/s41030-025-00326-x. Epub 2025 Oct 16.
- Background: PubMed 22155701Hasegawa K, Hagiwara Y, Chiba T, Watase H, Walls RM, Brown DF, Brown CA 3rd; Japanese Emergency Medicine Research Alliance. Emergency airway management in Japan: Interim analysis of a multi-center prospective observational study. Resuscitation. 2012 Apr;83(4):428-33. doi: 10.1016/j.resuscitation.2011.11.027. Epub 2011 Dec 8.
- Background: PubMed 40247381Maia IWA, Besen BAMP, Silva LOJE, von Hellmann R, Hajjar LA, Sandefur BJ, Pedrollo DF, Nogueira CG, Figueiredo NMP, Miranda CH, Martins D, Baumgratz TD, Bergesch B, Costa D, Colleoni O, Zanettini J, Freitas AP, Moreira NP, Gaspar PL, Tambelli R, Costa MC, Silveira S, Correia W, de Maria RG, Filho UAV, Weber AP, da Silva Castro V, Dornelles CFD, Tabach BS, Guimaraes HP, Stanzani G, Gava TF, Mullan A, Souza HP, Ranzani OT, Bellolio F, Alencar JCG; BARCO group. Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study. Crit Care. 2025 Apr 17;29(1):155. doi: 10.1186/s13054-025-05392-w.
- Background: PubMed 24099373Cho J, Cho YS, You JS, Lee HS, Kim H, Chung HS; Korean Emergency Airway Management Society. Current status of emergency airway management for elderly patients in Korea: Multicentre study using the Korean Emergency Airway Management Registry. Emerg Med Australas. 2013 Oct;25(5):439-44. doi: 10.1111/1742-6723.12122. Epub 2013 Sep 9.
- Background: PubMed 33684505April MD, Arana A, Reynolds JC, Carlson JN, Davis WT, Schauer SG, Oliver JJ, Summers SM, Long B, Walls RM, Brown CA 3rd; NEAR Investigators. Peri-intubation cardiac arrest in the Emergency Department: A National Emergency Airway Registry (NEAR) study. Resuscitation. 2021 May;162:403-411. doi: 10.1016/j.resuscitation.2021.02.039. Epub 2021 Mar 5.
- Background: PubMed 28582801Alkhouri H, Vassiliadis J, Murray M, Mackenzie J, Tzannes A, McCarthy S, Fogg T. Emergency airway management in Australian and New Zealand emergency departments: A multicentre descriptive study of 3710 emergency intubations. Emerg Med Australas. 2017 Oct;29(5):499-508. doi: 10.1111/1742-6723.12815. Epub 2017 Jun 5.
- Background: PubMed 33755076Russotto V, Myatra SN, Laffey JG, Tassistro E, Antolini L, Bauer P, Lascarrou JB, Szuldrzynski K, Camporota L, Pelosi P, Sorbello M, Higgs A, Greif R, Putensen C, Agvald-Ohman C, Chalkias A, Bokums K, Brewster D, Rossi E, Fumagalli R, Pesenti A, Foti G, Bellani G; INTUBE Study Investigators. Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries. JAMA. 2021 Mar 23;325(12):1164-1172. doi: 10.1001/jama.2021.1727.
- Individual participant dataSharing planned: No. De-identified data will be retained under institutional governance and are not currently planned for public individual participant data sharing.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Airway Management and Tracheal Intubation, run by Chang Gung Memorial Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact TING HAO YANG, Doctor (+886978989007, mr2434@cgmh.org.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of major adverse peri-intubation events within 30 minutes after the start of intubation (time frame: Periprocedural, through 30 minutes after the start of intubation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07574450, which also lists 7 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 May 2026.