Research institution
Chang Gung Memorial Hospital Clinical Trials
Studies where Chang Gung Memorial Hospital is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 146Stroke
Neuromodulation Combined With Dual FES Cycling and Cognitive Training After Stroke
This study will evaluate the effects of functional electrical stimulation (FES) cycling, cognitive task training, and non-invasive photobiomodulation on cognitive and upper-limb motor performance in adults after stroke.
- Trial name
- NCT07807176
- Testing
- Functional Electrical Stimulation Cycling, Cognitive Task Training, Transcutaneous Auricular Photobiomodulation
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Hepatocellular Carcinoma
PEARL Trial: Partial TACE Enhancing Anti-tumor Response With Lenvatinib in Unresectable HCC
This is a single-arm, open-label, phase II clinical trial. Patients with unresectable hepatocellular carcinoma (HCC) who are eligible for lenvatinib treatment will receive partial transarterial chemoembolization (TACE) targeting…
- Trial name
- Pearl (NCT07827807)
- Testing
- Lenvatinib, Partial transarterial chemoembolization (TACE)
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
HCC, Tace
Partial Immune-boost TACE in unrEseCTable HCC Patients Under Systemic Treatment
Study Objectives： Atezolizumab (anti-programmed death-ligand 1; anti-PD-L1) combined with bevacizumab (anti-vascular endothelial growth factor; anti-VEGF) or Durvalumab (anti-programmed death-ligand 1; anti-PD-L1) combined with…
- Conditions
- HCC, Tace, Immunotherapy
- Trial name
- EXPECT (NCT07168668)
- Testing
- Transarterial chemoembolization, durvalumab and tremelimumab
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Airway Response, Lung Transplant Recipients
Bronchial Response to Exercise After Double Lung Transplantation
This study aims to investigate the airway response to exercise and its association with breathlessness in double lung transplant recipients by comparing responses during 5-minute and 15-minute exercise durations.
- Conditions
- Airway Response, Lung Transplant Recipients, Lung Transplant, Challenge Test
- Trial name
- NCT07035743
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Insomnia Chronic, Hypnotics and Sedatives
Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia
Background: The prevalence of sedative-hypnotic use among middle-aged and older adults in Taiwan has continued to rise, highlighting the need to better understand the underlying factors contributing to sleep disturbances and…
- Conditions
- Insomnia Chronic, Hypnotics and Sedatives, Physical Activities
- Trial name
- NCT07896603
- Testing
- resistance training, Relaxation training
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Pain (Knee), Pain and Anxiety
A Comparison of Heart Rate Variability Biofeedback, Mindfulness, and Psychoeducation-based Interventions on Clinical Recovery Outcomes in Patients Undergoing Total Knee Arthroplasty
The goal of this clinical trial is to compare the effects of heart rate variability biofeedback (HRVB), mindfulness meditation, and psychological education in patients undergoing total knee arthroplasty (TKA).
- Conditions
- Pain (Knee), Pain and Anxiety, TKA
- Trial name
- NCT07896954
- Testing
- Heart rate variability biofeedback, Mindfulness, psychoeducation
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Long COVID
DAOIB for the Treatment of Brain Fog
This is a 24-week open trial. We will enroll long-COVID patients with cognitive impairments. All patients will receive DAOIB for 24 weeks.
- Trial name
- NCT05764538
- Testing
- DAOIB
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Radiation Treatment, Neurovascular Complications
Long-term Neurovascular Complications After Radiation Therapy in Head and Neck Cancer
Head and neck cancer is a group of cancers develop from the soft tissues, salivary gland, mucosa of the upper respiratory or digestive system covering the oral and nasal cavity.
- Trial name
- NCT06111430
- Where
- Taiwan
- Volunteers
- 800 people
- Sponsor
- Chang Gung Memorial Hospital
Sudden Hearing Loss
Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing Loss
Sudden sensorineural hearing loss (SSNHL) is diagnosed when there's a sudden drop in hearing of at least 30 decibels across three consecutive frequencies, emerging within up to 72 hours.
- Trial name
- NCT06467526
- Testing
- Hydroxychloroquine, Steroid
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Stroke (6 Months or More After Onset)
Co-Designed Digital Education and Peer Support for Young and Middle-Aged Stroke Survivors
Stroke survivors often experience persistent unmet needs during long-term recovery. Young and middle-aged stroke survivors may face additional challenges in balancing rehabilitation with work and family responsibilities.
- Trial name
- NCT07725666
- Testing
- Patient-Centered Digital Education and Peer Support Program, Usual Post-Stroke Care
- Volunteers
- 148 people
- Sponsor
- Chang Gung Memorial Hospital
Completed, with results posted
All 41Spastic Gait, Spastic
Exoskeleton Robotic Assisted Gait Training in Spastic Stroke Post Botulinum Toxin A Injection
The purpose of this project is to examine and compare the immediate and long-term effects of combined Botulinum toxin type A(BoNT-A) injection with exoskeleton Robotic assisted gait training (RABT) in patients with post-stroke…
- Trial name
- NCT06070987
- Testing
- BoNT-A injections, RF BoNT-A injection in first period and robot therapy, RF BoNT-A injection in second period and robot therapy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Prolonged Mechanical Ventilation, Protein Deficiency
High Protein, Core Muscle Rehab, Muscular Electrostimulation in Prolonged Mechanical Ventilation
The goal of this clinical trial is to learn about in patients with prolong mechanical ventilation. This main questions aims to answer are: High protein formula intake benefit in successful weaning from ventilator Core muscle…
- Trial name
- NCT05932134
- Testing
- UC + high protein diet (HP), UC + HP + core muscle rehabilitation, UC + HP + core muscle rehabilitation + neuromuscular electric stimulation (NMES)
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis
Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TEN
The goal of this study is to evaluate the effect of tofacitinib in patients with Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). The primary outcome of the study is the time to complete re-epithelialization.
- Trial name
- NCT06474078
- Testing
- Tofacitinib
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Chang Gung Memorial Hospital
Arthritis, Rheumatoid
Effects of a Rheumatoid Arthritis Self-management Program
Rheumatoid arthritis (RA) is a persistent systemic disease. WHO (World Health Organization) commented that a crucial goal of heath care for RA is prevention of loss of daily function by patients' self-management (SM) skills…
- Trial name
- NCT03470740
- Testing
- rheumatoid arthritis self-management program
- Where
- Taiwan
- Volunteers
- 224 people
- Sponsor
- Chang Gung Memorial Hospital
End-stage Renal Disease (ESRD)
Effect of Lifestyle Intervention in Patients With Chronic Kidney Disease on Fitness and Immune Function
To assess the efficacy of a 6-month lifestyle intervention in patients with end-stage renal disease(ESRD), we plan to conduct a self-controlled clinical trial. 34 participants receiving chronic HD will be enrolled.
- Trial name
- NCT05649657
- Testing
- Cyclic aerobic and resistance training
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chang Gung Memorial Hospital