Clinical trials: Intraoperative Monitoring
Postoperative Care
Perioperative Hemodynamic Optimization in High-Risk Patients Using Less-Invasive Monitoring Methods
The aim of this study is to evaluate different strategies of hemodynamic optimization in high risk surgical patients during the first twelve postoperative hours in ICU based on a protocol guided by a less invasive monitorig tool…
- Trial name
- NCT00375271
- Testing
- perioperative hemodynamic optimization protocol
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- Centro de Estudos Mário César de Rezende
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc
General Anesthesia, Intraoperative Monitoring
Analysis of Breath Sounds During Surgery
This study aims to analyze breath sounds during surgery by using electronic stethoscope sensors attached to patients under general anesthesia.
- Conditions
- General Anesthesia, Intraoperative Monitoring, Respiratory Sounds
- Trial name
- BREATHSOUND (NCT07280546)
- Testing
- Electronic stethoscope monitoring
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Hemodynamic Monitoring
The EU Hyprotect Registry
European, multicenter, prospective, observational registry in patients undergoing elective major non-cardiac surgery
- Trial name
- NCT04972266
- Testing
- AcumenTM Hypotension Prediction Index software
- Where
- 12 sites in France, Germany and 3 more
- Volunteers
- 702 people
- Sponsor
- Edwards Lifesciences
Pain, Chronic, Lumbar Radiculopathy
Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials
This is an observational pilot study. The spinal cord stimulator (SCS) procedure and neuromonitoring device is not under investigation. Neuromonitoring is typically performed on this patient population receiving SCS trials here.
- Conditions
- Pain, Chronic, Lumbar Radiculopathy, SCS
- Trial name
- SCS-Monitor (NCT05540756)
- Where
- United States
- Sponsor
- University of Chicago
Delirium, Anesthesia Awareness
Anesthesia Depth Increases Delirium Incidence
This study aimed to determine whether targeting bispectral index (BIS) readings of 55 (light anaesthesia) was associated with a lower incidence of delirium, dementia (POD), POCD and mortality but higher rates of awareness and…
- Trial name
- NCT05656703
- Testing
- BIS guidance of anesthesia, Standard of Care
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Heidelberg University
Remimazolam, Anesthesia Awareness
The Effect of Wavelet Index in Monitoring the Sedation Depth of Remimazolam Besylate
To explore the sedative effect of remimazolam in patients undergoing spinal anesthesia without pain stimulation. Both the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) and the Wavelet index (WLi) were used to…
- Conditions
- Remimazolam, Anesthesia Awareness, Sedative, Hypnotic, or Anxiolytic Withdrawal
- Trial name
- NCT06427785
- Testing
- Remimazolam besylate
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Esophageal Cancer
Visualization Versus Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerves During Thoracoscopic Esophagectomy
The clinical value of intraoperative nerve monitoring (IONM) in thoracoscopic esophagectomy remains uncertain. The aim of this randomized clinical trial was to compare the impact of RLN visualization versus IONM on their…
- Trial name
- NCT05199168
- Testing
- intraoperative nerve monitoring
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Surgery, Pain
Clinical Validation of Medasense Pain Response Index (PRI)
In our previous study, NCT01631695, we proposed and clinically evaluated the Medasense pain response index, PRI, in anesthetized patients undergoing surgery. Note: the name PRI has been changed to NoL (Nociception Level) Index.
- Trial name
- NCT01762332
- Testing
- Base level of remifentanil effect side concentration: 2ng/ml, Base level of remifentanil effect side concentration: 4ng/ml, chronic beta-blocker treatment
- Where
- Israel
- Volunteers
- 82 people
- Sponsor
- Medasense Biometrics Ltd
Nerve Conduction Study, Elective Surgery
Median Nerve Electromyography to Monitor Intraoperative Neuromuscular Function
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone.
- Conditions
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- Trial name
- NCT07571395
- Testing
- Electromyography
- Where
- Hungary
- Volunteers
- 45 people
- Sponsor
- Pongrácz Adrienn
Pain, Acute, Anesthesia
Pupillary Dilation Reflex Assessment for Intraoperative Analgesic Titration.
In this double blinded randomized controlled study, the pupillary dilation reflex is used for as a nociceptive indicator for opioid administration during elective surgery under general anesthesia.
- Trial name
- PUP-AIT (NCT03248908)
- Testing
- Pupillary dilation reflex, Standard of care
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Hospital, Antwerp
Colorectal Cancer, Diverticulitis of Sigmoid
Intraoperative Use of Oxygen Saturation Imaging to Assess Intestinal Perfusion
This will be a prospective, observational study of patients undergoing laparoscopic colorectal resection with anastomosis. After anastomosis creation and at the time of routine intraoperative flexible sigmoidoscopy, 4 mucosal…
- Trial name
- NCT07587619
- Testing
- Fujifilm monitoring
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Southern California
Intraoperative Neurophysiological Monitoring
Multi Modal Brain Monitoring and Cardiac Surgery
Multimodal brain monitoring is feasible and can be used in formulating therapeutic strategies during cardiac surgery. Such monitoring may help to improve patient outcome and to reduce costs after cardiac surgery with CPB.
- Trial name
- NCT02916069
- Testing
- Nearinfrared Spectroscopy (NIRS), Transcranial Doppler (TCD), Bispectral index (BIS)
- Where
- Egypt
- Volunteers
- 1,200 people
- Sponsor
- Assiut University
Hemodynamic Monitoring
Comparison of Transthoracic Electrical Bioimpedance and Pulse Contour Analysis in Renal Transplantation Patients
Hemodynamics monitoring using non-invasive transthoracic electrical bioimpedance ICON are compatible with standard invasive monitoring using pulse contour analysis EV1000
- Trial name
- NCT03893513
- Testing
- Transthoracic Electrical Bioimpedance, Pulse Contour Analysis
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dita Aditianingsih
Flap Ischemia, Hypoxia
Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap Reconstructions
This study is a single-center, observational study designed to collect tissue spectrometric data.
- Trial name
- NCT07786610
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Cerebral Oxygen Desaturation
Cerebral Oxygen Monitoring During Surgery and Recovery After Surgery in Patients Having Lung Surgery
The current study proposes to address the question of whether patients' cerebral oxygen saturation levels are predictive of their recovery from thoracic surgery.
- Trial name
- NCT01835327
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Thyroid Surgery Intraoperative Nerve Monitoring (IONM) Recurrent Laryngeal Nerve Function Dexmedetomidine vs Midazolam (Anesthetic Agents)
EFFECT OF DEXMEDETOMİDİNE ON RECURRENT LARYNGEAL NERVE MONİTORİNG: A COMPARATİVE STUDY WİTH MİDAZOLAM
This prospective observational study evaluated the effect of dexmedetomidine compared with midazolam on intraoperative monitoring of the recurrent laryngeal nerve during thyroid surgery.
- Trial name
- DEX-RLN (NCT07195214)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Amasya University
Brain Injury, Neurosurgery
Electrocorticographic Monitoring of Brain Retraction Injury (EMBRI)
A single centre IDEAL Stage 1 feasibility study using novel electrophysiological recording techniques in adult participants undergoing neurosurgery.
- Conditions
- Brain Injury, Neurosurgery, Brain Ischemia
- Trial name
- EMBRI (NCT06409806)
- Testing
- ECOG Array
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University College, London
Vital Signs
The Use of Portable Wireless Monitor in Patient Vital Sign Monitoring
This clinical investigation assesses the performance of PaMo patient monitor system (PaMo) and its wearable sensing devices that combines continuous IP, ECG and PPG in detecting developing respiratory depression episodes.
- Trial name
- NCT06117111
- Testing
- PaMo monitoring device
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Orthopedic Surgery, Total Hip Prosthesis
Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive and Psychomotor Functions in Output Post Interventional Room Monitoring - COGNIDES
The recovery of cognitive and psychomotor functions is best performed under anesthesia after desflurane when propofol in that obtaining a Aldrete score> 8/10 output of the allowing SSPI.
- Conditions
- Orthopedic Surgery, Total Hip Prosthesis, Total Knee Replacement
- Trial name
- Cognides (NCT02036736)
- Testing
- Intraoperative anesthetic strategy by Propofol, Intraoperative anesthetic strategy by Desflurane
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris