Nerve Conduction StudyNCT07571395
Median Nerve Electromyography to Monitor Intraoperative Neuromuscular Function
An observational study of Nerve Conduction Study and Elective Surgery, run by Pongrácz Adrienn at 1 site in Hungary.
Trial summary
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- What is being tested?
- Electromyography
- How many people
- 45 participants
- Where
- 1 siteHungary
- Study dates
- 16 Jun 2026to 31 Mar 2028
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients undergoing elective surgery that requires one dose of non-depolarising neuromuscular blocking agent, whose arms are accessible for intraoperative neuromuscular blockade monitoring.
Who may be able to join
- ASA I-III physical status
- elective surgery requiring muscle relaxation
- both arms are available during surgery in the same position for neuromuscular blockade monitoring
- signed informed consent form
Who cannot join
- neruomuscular disorder in patient history (eg. stroke, myasthenia)
- innervation problem in either arms (eg. carpal tunnel syndrome)
- deformity to either arms (eg. Dupyurten contracture, severe arthritis)
- Severe hepatic or renal insufficiency that affects muscle relaxant pharmacokinetics
- skin lesions at the site of electrode placement
- implanted pacemaker jelenléte
- gravidity
- muscle relaxant needs to be repeated during surgery
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Hungary1 site, 1 recruiting
- Recruiting
University of Debrecen Medical Center, Department of Anesthesiology and Intensive Care
Debrecen, 4032
Reka Nemes, MD PhD, +36309668722
About this study
Official title: Comparative Examination of Ulnar and Median Nerve Electromyography Examinations to Monitor Intraoperative Neuromuscular Function
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. These monitors stimulate the ulnar nerve in the wrist and examine the evoked muscle response. The aim of this study is to examine the usability of another nerve in the wrist, the median nerve.
- Conditions
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- Being tested
- Electromyography
- Keywords
- electromyography, neuromuscular blockade monitoring, median nerve
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ElectromyographyDiagnostic test
Electromyographic examination of the median and ulnar nerves to monitor intraoperative neuromuscular blockade
| Study group | Role | What they receive |
|---|---|---|
| Median nerve examination | Median nerves in the dominant and non-dominant hands are are examined Receives: Diagnostic Test: Electromyography | |
| Ulnar nerve examination | Ulnar nerves in the dominant and non-dominant hands are examined Receives: Diagnostic Test: Electromyography |
What is being measured
The primary outcome is the main question the study is designed to answer.
CMAP
Comparison of compound muscle action potential amplitudes evoked by median and ulnar nerve stimulation and measured at the thenar
Measured: Baseline
Secondary outcomes (2)
Recovery time
Time from muscle relaxant administration to spontaneous recovery to TOFR>0,9 monitored with median and ulnar nerve stimulation
Measured: Perioperative
Onset time
Time from administration of muscle relaxant to disappearance of twitch response (TOFC0) monitored with median and ulnar nerve stimulation
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2026
- Study start16 Jun 2026
- Primary completion31 Mar 2028 (estimated)
- Study completion31 Mar 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nerve Conduction StudyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Pongrácz Adrienn
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Pongrácz Adrienn, University of Debrecen
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07571395
- Sponsor's protocol ID
- AITT 2026/1
- Status last verified
- Jun 2026
- First submitted
- 21 Apr 2026
- Last updated
- 17 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No