Clinical trials: Intraoperative Monitoring
Lumbar Disc Disease
Intra-operatory Neurophysiological Monitoring Changes as a Predictive Clinical Outcome Measure in Lumbar Radiculopathy.
The purpose of this study is to determine the relation among: (1) changes in voltage and amplitude of trans-operatory records obtained through the use of Intra-operative Neurophysiological Monitoring (IONM), and (2) clinical…
- Trial name
- NCT02185508
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- American British Cowdray Medical Center
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Urinary Incontinence, Erectile Dysfunction
Intraoperative Nerve Monitoring During Robot-assisted Laparoscopic Prostatectomy
The purpose of this study is to determine whether the use of intraoperative nerve monitoring during robotic-assisted laparoscopic prostatectomy surgery improves post-surgery urinary continence and erectile function.
- Trial name
- NCT02446808
- Testing
- Intraoperative nerve monitoring
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ProPep Surgical, LLC
Femoral Neck Fractures
Intraoperative Monitoring of Femoral Head Perfusion
An ICP monitor will be used to record blood flow/perfusion of the femoral head following fixation of femoral neck fractures. FDA approved device but not for this use.
- Trial name
- NCT04110639
- Testing
- Intracranial pressure (ICP) monitor, Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Healthcare of Atlanta
Aortic Aneurysm, Thoracic
Neurophysiological Intraoperative Monitoring During Aortic Surgery
The primary objective of this study is to evaluate if the motor-evoked potentials/motor action potential amplitude ratio and motor action potential amplitude measurement are useful in detecting spinal cord ischemia during…
- Trial name
- NIMAS (NCT02644681)
- Testing
- Aortic Aneurysm, Thoracic surgery
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Scientific Institute San Raffaele
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Spinal Cord Associative Plasticity Study
Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- SCAP (NCT05163639)
- Testing
- Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cervical Stenosis, Disk, Herniated
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we…
- Conditions
- Cervical Stenosis, Disk, Herniated, Spondylosis
- Trial name
- NCT05356286
- Testing
- epidural electrical stimulation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Nociception, NOL Index
Nociception Monitoring During Cardiac Surgery
Cardiac surgery is frequently a source of acute or chronic pain. According to the International Association for the Study of Pain (IASP), nociception is defined as "the neural mechanisms of encoding and processing harmful…
- Conditions
- Nociception, NOL Index, Cardiac Surgery
- Trial name
- MoNOLcard (NCT06817005)
- Testing
- Intervention arm
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Undetected Intraoperative Blood Loss
Intra-operative Monitoring of Blood Loss
Certain types of surgery are associated with occult blood loss, which is hard to detect intraoperatively by intermittent conventional, invasive Hb concentration measurements using the clinical standard of Hb monitoring by…
- Trial name
- NCT01864980
- Testing
- blood transfusion, intermittent Hbsatlab measurement, blood transfusion, based on continuous SpHb readings
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Intraoperative Hemodynamics
Physiological Reference Values of Total Arterial Impedance Derived From PRAM Monitoring
Total arterial impedance (Ztot) is an advanced hemodynamic parameter that reflects the global arterial load opposing ventricular ejection by integrating both steady and pulsatile components of the arterial system.
- Trial name
- PRAM-ZTOT (NCT07340333)
- Where
- Turkey (Türkiye)
- Volunteers
- 437 people
- Sponsor
- Ataturk University
Surgery, Temperature Change, Body
Intraoperative Body Core Temperature Monitoring: Oesophageal Probe vs Heated Controlled Servo Sensor
Monitoring of intraoperative core temperature is essential for patient safety, reducing the risk of perioperative hypothermia. A recently developed measuring system, SpotOn® (3M, St.
- Trial name
- ESOSPOT (NCT03820232)
- Testing
- temperature monitoring
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Careggi Hospital
Hyperthermia, Colorectal Neoplasms
Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC
The objective of our PILOT study is to evaluate the impact of a controlled (monitored) randomized anesthesia during cytoreductive surgery with HIPEC to oxaliplatin in order to treat adenocarcinomas of colorectal origin.
- Conditions
- Hyperthermia, Colorectal Neoplasms, Oxaliplatin
- Trial name
- CHIPNOL (NCT04104334)
- Testing
- Remifentanil infusion, desflurane titration and fluid infusion will be guided by NOL index, BIS index and Flotrac EV1000 system respectively, Remifentanil infusion and desflurane titration will be guided by anesthesia usual practices
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Pain
Evaluation of NoL Index and ANI After Nociceptive Stimulation at Different Infusion Rates of Remifentanil Infusion
Contrary to "immobility" and, to a lesser extent, to the "hypnosis/unconsciousness" component of general anaesthesia, the monitoring of "analgesia" remains largely elusive, evaluated mainly through poorly sensitive and…
- Trial name
- NCT02602379
- Testing
- Tetanic stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital