Clinical trials: Intraoperative Bleeding
Rhinosinusitis Chronic, Bleeding
This Study Aims to Assess the Impact of 50°C Saline Irrigation on the Overall Intraoperative Blood Loss and Surgical Visualization During Endoscopic Sinus Surgery for Rhinosinusitis.
Objectives: Intraoperative bleeding during endoscopic sinus surgery for severe rhinosinusitis may significantly compromise the surgical field.
- Trial name
- NCT07627789
- Testing
- Hot saline irrigation, Room-temperature saline irrigation
- Where
- Poland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Military Institute of Aviation Medicine
Verapamil, Diltiazim
Efficacy of Oral Verapamil and Oral Diltiazim on Reduction of Intraoperative Bleeding During Endoscopic Sinus Surgery Under General Anesthesia
To study the effect of addition of oral verapamil or Diltiazim to general anaesthesia on the Intraoperative haemodynamics : heart rate(HR), noninvasive blood pressure(NIBP), mean arterial blood pressure(MAP), and the blood loss…
- Conditions
- Verapamil, Diltiazim, FESS
- Trial name
- NCT04790331
- Testing
- Verapamil, Diltiazem
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intraoperative Bleeding, Post-operative Bleeding
Study to Compare the Addition of Floseal to Our Standard of Care to Control Post Operative Bleeding in TKR
The purpose of this study is to compare Floseal to our standard of care (SOC) to decrease intraoperative and immediate post-operative bleeding.
- Trial name
- NCT01891461
- Testing
- Floseal
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Periapical Lesion
Effect of Piezoelectric Device on Intraoperative Hemorrhage Control and Quality of Life
Most osteotomies and apicoectomies in periapical surgeries are performed by surgical carbide or diamond burs. But greater pressure is applied during cutting which causes more thermal and mechanical damage to the bone.
- Trial name
- NCT06240182
- Testing
- conventional surgery, piezoelectric device
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Spine Fracture
Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery
Reduction of intra-operative blood loss
- Trial name
- NCT05294926
- Testing
- Rocuronium, nerve stimulator
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University
Leiomyoma, Uterine, Intraoperative Blood Loss
Intravenous Tranexamic Acid and Intramyometrial Desmopressin Effect on Blood Loss During Laparoscopic Myomectomy.
To evaluate the effect of intravenous tranexamic acid plus intramyometrial desmopressin administration on perioperative blood loss and blood transfusion need in laparoscopic myomectomy operation.
- Trial name
- NCT05517590
- Testing
- Tranexamic acid, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Blood Loss, Surgical, Transfusion
Blood Loss Evaluation Using a Novel Device
The study´s aim is to evaluate the clinical applicability of the Feature Extraction Technology (FET) during a simulated blood loss scenario.
- Conditions
- Blood Loss, Surgical, Transfusion, Patient Blood Management
- Trial name
- NCT04245995
- Testing
- Feature Extraction Technology
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Intra-operative Bleeding
Can Head Position Improve Surgical Field During Ear Surgery?
Middle ear surgeries utilizes microscope in a narrow field. They are better performed under controlled hypotension, to minimize bleeding and improve surgical field visualization and hence improve results.Head-up or…
- Trial name
- NCT04095754
- Testing
- Head-Up Position, Dexmedetomidine, Induction and maintenance of anaesthesia
- Where
- 2 sites in Egypt
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Blood Loss, Surgical, Blood Transfusion
Bleeding in Knee Arthroplasty After Preconditioning With Sevoflurane
Knee arthroplasty is performed with restriction of blood flow by use of the pressure tourniquet. Ischemia of skeletal musculature is accompanied by the formation of reactive oxygen species and release of vasoactive factors.
- Trial name
- NCT03379103
- Testing
- Sevoflurane, Propofol
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Rotator Cuff Tears, Hemorrhage, Surgical
Effect of Intravenous Tranexamic Acid on Visual Clarity During Shoulder Arthroscopy in the Beach Chair Position
Shoulder arthroscopy offers numerous advantages and has led to a continuous increase in procedural complexity. Adequate intraoperative visual clarity is essential for successful performance of the procedure and is primarily…
- Conditions
- Rotator Cuff Tears, Hemorrhage, Surgical, Shoulder Injuries
- Trial name
- NCT05397652
- Testing
- Tranexamic Acid Injectable Product
- Where
- Croatia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Nikola Matejcic
Blood Loss, Surgical
Ergot and Oxytocin During Cesarean Delivery Following Failure to Progress in Labour
Despite of marked improvements in clinical management, early postpartum hemorrhage(PPH)remains a significant contributor to maternal morbidity and mortality both in developing countries and in hospitals equipped with all that…
- Trial name
- NCT00481533
- Testing
- Methyl-Ergonovine-Oxytocin, Oxytocin
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Impacted Third Molar Tooth, Adverse Reaction to Other Local Anesthetics
Lower Third Molar Removal With 2% and 4% Articaine
The present clinical trial randomized compared the clinical efficacy of the local anesthetics articaine in two concentrations, 2% and 4%, in association with 1:200,000 adrenaline, for the removal of lower third molars.
- Trial name
- NCT02457325
- Testing
- Surgery with 2%Articaine first, then Surgery with 4% Articaine, Surgery with 4%Articaine first, then Surgery with 2% Articaine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Placenta Accreta Spectrum
Role of Uterotonics in Reducing Intraoperative Blood Loss in Patients With PASD Undergoing Cesarean Hysterectomy
Objectives: To evaluate the effect of oxytocin in reducing intraoperative blood loss in patients with PAS disorders planned for cesarean hysterectomy.
- Trial name
- NCT06493968
- Testing
- oxytocin
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteogenesis Imperfecta
Tranexamic Acid During Telescoping Nail Application In Osteogenesis Imperfecta
The aim of this study is to assess the effective of intraoperative use of tranexamic acid in reducing blood loss during telescoping nail application in cases of osteogenesis imperfecta.
- Trial name
- NCT05321199
- Testing
- Tranexamic acid
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Rhinosinusitis (CRS) with and Without Nasal Polyps
Correlation of Preoperative Indices (serum Vit D, Calcium, Phosphorus, FAR, PLR, SII) on Intraoperative Bleeding in CRS
The purpose of this observational study was to examine whether preoperative indicators correlate with intraoperative bleeding to facilitate control of intraoperative bleeding.
- Trial name
- NCT06737198
- Testing
- without interventios.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
BPH With Urinary Obstruction, BPH
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines.
- Conditions
- BPH With Urinary Obstruction, BPH, Hematuria, Same Day Discharge
- Trial name
- NCT05620784
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Blood Loss, Surgical
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
The uterine fibroids are the most common benign tumors found in the female reproductive system. Uterine fibroids commonly cause heavy menstrual periods.
- Trial name
- NCT07721623
- Testing
- Carbetocin
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Alex Ekwueme Federal University Teaching Hospital
Surgical Blood Loss, Third Molar
Effect of Warm Saline Irrigation on Bleeding in Mandibular Third Molar Surgery
The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.
- Trial name
- NCT04143373
- Testing
- warm saline irrigation
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Blood Loss, Surgical, Blood Loss, Postoperative
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate, Pre-operative Administration.
- Trial name
- NCT04656067
- Testing
- Oxytocin ,Tranexamic acid and Ethamsylate
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Blood Loss, Surgical, Transfusion Rate
Effect of Electrosurgery on Blood Loss and Intraoperative Transfusions in Musculoskeletal Tumor Surgery
Resection of malign musculoskeletal tumors and reconstruction with large tumor prostheses often results in relevant blood loss requiring hemodynamic stabilization and transfusion.
- Conditions
- Blood Loss, Surgical, Transfusion Rate, Electrosurgery, Tumororthopaedics
- Trial name
- NCT05164809
- Testing
- Application of novel electrodes
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster