Clinical trials: Intraocular Pressure
Ocular Hypertension
A Retrospective Evaluation of the Intraocular Pressure Spikes With Loteprednol and Loteprednol/Tobramycin
Patient charts will be reviewed to evaluate the incidence of intraocular pressure spikes while on Loteprednol etabonate ophthalmic suspension 0.5%, Loteprednol etabonate (0.5%) and tobramycin (0.3%)
- Trial name
- NCT00834171
- Testing
- Loteprednol etabonate ophthalmic suspension 0.5%, Loteprednol etabonate (0.5%) and tobramycin (0.3%).
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Allergan
Intraocular Pressure
The Effect of Ocular Massage on the Management of Elevated Intraocular Pressure After Acute Angle Closure
Lowering intraocular pressure remains the mainstay of therapy in the management of glaucoma. The effect of ocular massage on intraocular pressure in patients with acute primary angle closure was the important thing.This was a…
- Trial name
- NCT02539758
- Testing
- ocular massage, LenstarLS900, Goldmann tonometer
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Lv Yingjuan
Ocular Hypertension, Open-angle Glaucoma
Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension
Evaluation of the ocular hypotensive efficacy and safety of Netarsudil (AR-13324) Ophthalmic Solution compared to Timolol Maleate Ophthalmic Solution
- Trial name
- NCT02207621
- Testing
- AR-13324 Ophthalmic Solution 0.02%, Timolol maleate Ophthalmic Solution 0.5% BID, AR-13324 Ophthalmic Solution 0.02% BID
- Where
- United States
- Volunteers
- 756 people
- Sponsor
- Aerie Pharmaceuticals
Normal Tension Glaucoma
IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic
The primary purpose of this study is to determine whether topical ophthalmic anesthetics lower the intraocular pressure in the eye.
- Trial name
- NCT01254149
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Glaucoma
Response to SLT vs. ALT in Patients Under 60 Years of Age
Laser trabeculoplasty is a routine treatment for glaucoma and can be performed with either argon (ALT) or selective Yag (SLT) lasers.
- Trial name
- NCT01087684
- Testing
- Argon laser trabeculoplasty, Selective laser trabeculoplasty
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Sunnybrook Health Sciences Centre
Intraocular Pressure
The Response of Intraocular Pressure to Systemic Hypercapnia and Hyperoxia
The purpose of this study is to determine how intraocular pressure responds to changes in the levels of carbon dioxide or oxygen that a healthy individual inspires.
- Trial name
- NCT01325285
- Testing
- RespirAct
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Glaucoma
Glaucoma Screening to Enhance At-Risk Californians' Health
The vast majority of glaucoma cases in the United States go undetected and untreated until the late stages of the disease. Open-angle glaucoma is a progressive condition that is asymptomatic in its early to moderate stages and…
- Trial name
- G-SEARCH (NCT06854198)
- Testing
- Glaucoma screening with optical coherence tomography (OCT), color fundus photography, and tonometry, Educational Brochure
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Glaucoma
Trabeculectomy With Ologen
Trabeculectomy is the gold standard procedure for the surgical treatment of glaucoma. Antimetabolites such as mitomycin-C (MMC)are widely used as an adjunctive during surgery to prevent scarring of the bleb.
- Trial name
- NCT01753492
- Testing
- Ologen
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Maastricht University Medical Center
Myopia
Corneal Biomechanics Study
The goal of the study is to investigate relationship between the corneal response to a temporary increase in intraocular pressure and corneal mechanical properties.
- Trial name
- NCT03658239
- Testing
- Inversion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Intraocular Pressure, Oncology
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in…
- Trial name
- NCT04281017
- Testing
- TIVA, Balanced anesthesia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Heart Failure With Preserved Ejection Fraction, Diastolic Heart Failure
Classification of Heart Failure With Preserved Ejection Fraction
The purpose of this study is to create a classification system for the heterogenous disorder of heart failure with preserved ejection fraction (HFpEF).
- Trial name
- NCT01030991
- Where
- United States
- Volunteers
- 514 people
- Sponsor
- Northwestern University
Primary Open Angle Glaucoma, Intraocular Pressure
Microinvasive Glaucoma Surgery -The Lowering Effect of Intraocular Pressure on Glaucoma Patients With High Frequency Deep Sclerotomy
Highlights the high-frequency deep sclerotomy (HFDS) as a promising ab-interno surgery in primary open-angle glaucoma (POAG) patients and evaluates the efficacy and safety of the procedure.
- Conditions
- Primary Open Angle Glaucoma, Intraocular Pressure, Glaucoma Surgery
- Trial name
- HFDS (NCT05466526)
- Testing
- High frequency deep sclerotomy (HFDS)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Intraocular Pressure
Efficacy of Latanoprostene Bunod in Lowering Intraocular Pressure in Japanese Healthy Male Volunteers
The objective of this study is to evaluate the effect of latanoprostene bunod dosed once daily (QD) in reducing intraocular pressure (IOP) measured over a 24-hour period in healthy subjects.
- Trial name
- KRONUS (NCT01895985)
- Testing
- Latanoprostene bunod
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Glaucoma, Ocular Hypertension
SD-OCT Multimodal Analysis in GLaucoma
Glaucoma is the first cause of irreversible blindness worldwide with more than 60 millions people affected in 2010. It is defined as a neurodegenerative disease characterized by a progressive loss of retinal ganglion cells (RGC)…
- Conditions
- Glaucoma, Ocular Hypertension, Eye Diseases
- Trial name
- SOMAL (NCT02710916)
- Testing
- SD-OCT Spectralis
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Glaucoma
SENSIMED Triggerfish in Closed Eyes
This study investigates the effect of eye opening/closure on the quality of IOP (intraocular pressure) related patterns recorded with SENSIMED Triggerfish.
- Trial name
- NCT01938287
- Testing
- SENSIMED Triggerfish
- Where
- Switzerland
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Primary Open Angle Glaucoma
The Effects of Caffeinated Coffee on Intraocular Pressure
High intraocular pressure (IOP) is a known risk factor for developing primary open-angle glaucoma (POAG). There is controversy in the literature regarding the degree to which caffeine influences IOP, with some studies reporting…
- Trial name
- NCT01364207
- Testing
- Caffeinated Coffee, Decaffeinated Coffee
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Glaucoma
Switching From Preserved to Preserved-free Treatments for Glaucoma.
A 1-year prospective, randomized, investigator-masked trial comparing the confocal and clinical effects of treatment with unpreserved prostaglandins (tafluprost) versus preserved prostaglandins (latanoprost) in newly-diagnosed…
- Trial name
- NCT01433900
- Testing
- Tafluprost, Latanoprost
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Paolo Fogagnolo
Coronary Artery Disease
Non-Invasive EndoPAT Increases Diagnostic Yield of CAD by Coronary Angiography
The purpose of this study is to assess the non-invasive, Peripheral Arterial Tonometry (PAT) testing as another way of predicting potential coronary artery blockages in the heart.
- Trial name
- NCT01581671
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Mayo Clinic
Glaucoma
Steroids Versus Non-steroidal Anti-inflammatory Drugs Following Glaucoma Surgery
This study aims to evaluate the eye pressure response to non-steroidal anti-inflammatory eye drops as compared to steroid eye drops following glaucoma surgery.
- Trial name
- NCT00956462
- Testing
- Ketorolac (NSAID) versus Dexamethasone (steroid)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University Health Network, Toronto
Glaucoma, Open-Angle
Evaluating Home Testing Devices for the Management of Glaucoma
With the advancement in technology we have the opportunity of performing the glaucoma testing at home to monitor the disease. The purpose of this study is evaluating the feasibility and patient acceptance of home testing with…
- Trial name
- NCT05325996
- Testing
- Standard Automatic Perimetry Humphrey Field Analyzer, visuALL H, iCare Home Tonometer
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Wills Eye