Clinical trials: Intraocular Lens, open to volunteers
Cataract, Presbyopia
Clinical Study to Evaluate the LensGen® Juvene® Intraocular Lens
To assess the safety and effectiveness of the Juvene® IOL for the treatment of aphakia and mitigation of the effects of presbyopia after removal of the natural crystalline lens due to cataract.
- Trial name
- Nirvana (NCT05364983)
- Testing
- Juvene IOL, Tecnis® Monofocal (ZCB00, PCB00 or DCB00)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
IOL, Cataract
Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery
The goal of this post-market, prospective study at multiple clinics is to evaluate the rotational stability of the RayOne Model RAO800S non-toric monofocal intraocular lens with orientation marks in adult patients undergoing…
- Trial name
- NCT07099079
- Volunteers
- 92 people
- Sponsor
- Rayner Intraocular Lenses Limited
Glaucoma, Ocular Hypertension
Evaluation of the Safety, Efficacy, Dose Response of the Bimatoprost Drug Ring System (BIM-DRS) in Pseudophakic Patients Diagnosed With Open Angle Glaucoma or Ocular Hypertension
The goal of this clinical trial is to learn if two different doses of the SpyGlass Bimatoprost-Drug Ring System (BIM-DRS) work to treat adult pseudophakic patients with either glaucoma or ocular hypertension.
- Trial name
- NCT07641296
- Testing
- BIM-DRS Low Dose, BIM-DRS High Dose, SpyGlass IOL with silicone pads (no drug)
- Volunteers
- 24 people
- Sponsor
- SpyGlass Pharma, Inc.
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Glaucoma, Ocular Hypertension
Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry
While elevated intraocular pressure (IOP) is no longer part of the definition of glaucoma it remains the sole proven modifiable risk factor for the onset and progression of glaucoma.
- Trial name
- NCT04024293
- Testing
- Goldfish (GF)
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Sensimed AG
Aphakia Cataract
Clinical Evaluation of the Adaptilens Accommodating IOL
The goals of this feasibility study are to learn more about the performance of the intraocular lens (IOL), if the IOL is safe for use, and what the best surgical techniques are for implanting the IOL in patients who require…
- Trial name
- NCT07607860
- Testing
- Accomodating Intra Ocular Lens, Monofocal Intra Ocular Lens
- Volunteers
- 100 people
- Sponsor
- Adaptilens, Inc.
Cataract Surgery
Clinical Investigation of IXIUM TWIN Viscoelastic Ophthalmic Device For Cataract Surgery
This clinical trial is testing a new surgical gel called IXIUM TWIN, designed to protect the eye during cataract surgery. Cataracts, which cloud the eye's natural lens, are the leading cause of vision loss worldwide.
- Trial name
- IXIUM_TWIN (NCT07279506)
- Testing
- IXIUM TWIN, HEALON
- Volunteers
- 180 people
- Sponsor
- LCA Pharmaceutical
Intraocular Lens, Cataract
Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic
Cataracts are cloudy areas in the lens of the eye that can cause changes in vision. Symptoms of cataracts include cloudy or fuzzy vision and sensitivity to glare.
- Conditions
- Intraocular Lens, Cataract, Presbyopia
- Trial name
- NCT05955846
- Testing
- cataract surgery, implantation of device IOL FG-80030.1
- Where
- 8 sites in Portugal, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Z Optics, Inc.
Aphakia
Bicentric Clinical Investigation to Assess Safety and Performance of LuxBoost IOL
The study purpose is to demonstrate safety and performance of bilateral implantation of LuxBoost intraocular lenses compared with the LuxGood Monofocal lens.
- Trial name
- LuxBoost (NCT06258707)
- Testing
- LuxBoost IOL, LuxGood IOL
- Where
- 2 sites in France
- Volunteers
- 58 people
- Sponsor
- Cutting Edge SAS
Glaucoma, Ocular Hypertension
Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
The goal of this clinical trial is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma or ocular hypertension and requiring cataract surgery.
- Trial name
- NCT07036510
- Testing
- TimoD implant, Injector system, Timolol eye drops 0.5%
- Where
- Panama
- Volunteers
- 42 people
- Sponsor
- EyeD Pharma
Aphakia, Postcataract
Trial to Investigate the Safety and Effectiveness of the KI-362-US1 (YP2.2VM) Intraocular Lens (IOL) in Adult Participants for Correction of Aphakia Following Cataract Extraction
This study is designed to evaluate how well an artificial lens, called an intraocular lens (IOL), performs in adults undergoing cataract surgery.
- Trial name
- NCT07650201
- Testing
- KI-362-US1 (YP2.2VM)
- Where
- 9 sites in United States
- Volunteers
- 340 people
- Sponsor
- Kowa Research Institute, Inc.
Postoperative Visual Outcomes Following Cataract Surgery in Patients With Prior Myopic Corneal Laser Vision Correction
Evaluation of Cataract Surgery Outcomes in Patients With Prior Laser Vision Correction Implanted With the CT LUCIA Lens
This is a prospective, Phase IV, post-approval observational study evaluating postoperative outcomes in patients with a history of myopic corneal laser vision correction (LVC) undergoing bilateral cataract surgery with…
- Trial name
- NCT07084545
- Testing
- CT LUCIA 621P Intraocular Lens Implantation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Lens Implantation, Intraocular
Comparative Clinical Study of Intraocular Lens Injectors Lioli™, Pioli™, and Pioli™ Plus
The goal of this observational study is to evaluate whether different intraocular lens (IOL) injectors affect surgical outcomes in patients aged 40 and older undergoing cataract surgery.
- Trial name
- NCT07140029
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- AST Products, Inc.
Cataract
Multicentric Clinical Investigation to Assess Safety and Performance of Lux HighAdd IOL
The study purpose is to demonstrate safety and performance of bilateral implantation of LuxHighAdd intraocular lens compared with the LuxGood Monofocal lens.
- Trial name
- HIGHADD (NCT06446817)
- Testing
- LuxHighAdd IOL, LuxGood IOL
- Where
- 3 sites in France
- Volunteers
- 57 people
- Sponsor
- Cutting Edge SAS
Presbyopia Correction, Astigmatism
A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery
To evaluate the clinical outcomes and patient satisfaction of two commercially available trifocal toric intraocular lenses Primary Objective: To compare the distance-corrected intermediate visual acuity between the two trifocal…
- Conditions
- Presbyopia Correction, Astigmatism, Cataract
- Trial name
- NCT07232615
- Testing
- Optiflex TRIO Intraocular Lens, AcrySof® IQ PanOptix®
- Where
- 6 sites in Germany, India and 1 more
- Volunteers
- 138 people
- Sponsor
- Biotech Healthcare Holding Gmbh