Clinical trials: Intra-abdominal Surgery
Surgical Site Infection, Bleeding
Mild Hypothermia Influence on Patient Outcome in Major Abdominal Surgery
This study investigate associations between mild hypothermia (patients' core temperature ≤ 36.0 degrees Celsius) and intra-operative blood loss and surgical site infections (SSI) in patients undergoing major abdominal surgery.
- Trial name
- NCT03112317
- Testing
- Prevention of hypothermia
- Where
- 2 sites in Norway
- Volunteers
- 3,059 people
- Sponsor
- Haukeland University Hospital
Intra-abdominal Perforation
the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations
This prospective intended to observe the influence of prophylactic and empirical anti-fungal treatment on Severe Sepsis patients with perforations.
- Trial name
- NCT02941068
- Testing
- fluconazole and caspofungin
- Volunteers
- 223 people
- Sponsor
- Nanjing PLA General Hospital
Abdominal Cancer
Vessel- and Bone-based Ultrasound Registration
In this study we aim to develop an automatic artery and bone segmentation algorithm, which is required for future clinical implementation of US registration for surgical navigation.
- Trial name
- NCT05637346
- Testing
- Intra-operative ultrasound measurement
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- The Netherlands Cancer Institute
Laparoscopic Abdominal Surgery
Pre-operative Carbohydrate Drink to Preserve Peri-operative Insulin Sensitivity
Enhanced Recovery after Surgery (ERAS) pathways include multiple evidence-based interventions delivered throughout the peri-operative period that aim to attenuate the surgical stress response and support rapid physiologic and…
- Trial name
- NCT02673502
- Testing
- simple carbohydrate drink, complex carbohydrate drink
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Postoperative Infection, Abdominal Surgery
Study for Rapid Diagnosis of Postoperative Abdominal Infection
This is a prospective and exploratory study, which utilizes non-targeted metagenomic next-generation sequencing (mNGS) detecting drain fluid from patients who are suspected of postoperative abdominal infection.
- Conditions
- Postoperative Infection, Abdominal Surgery, Intra-abdominal Infection, Postoperative Fever
- Trial name
- NCT05187871
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Surgical Blood Loss, Transfusion-dependent Anemia
Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery
The goal of this clinical trial is to learn if the administration of tranexamic acid can reduce the necessity of blood transfusions in adult patients undergoing major abdominal surgery. .
- Conditions
- Surgical Blood Loss, Transfusion-dependent Anemia, Abdomen Disease
- Trial name
- TATRA (NCT06414031)
- Testing
- Tranexamic Acid
- Where
- 2 sites in Germany
- Volunteers
- 892 people
- Sponsor
- Ulrich Ronellenfitsch, MD
Ileus, Post-Operative Adhesions
A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection
The purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of post-operative ileus and intra-abdominal adhesions in subjects undergoing elective bowel…
- Trial name
- PROFILE (NCT02836470)
- Testing
- LB1148
- Where
- 28 sites in United States
- Volunteers
- 112 people
- Sponsor
- Palisade Bio
Abdominal Cancer
Peri-operative Rectus Sheath Block Versus TEA Abdominal Surgeries
Thoracic epidural analgesia (TEA) can be considered the gold standard for postoperative analgesia in major abdominal surgeries, as proved by a lot of number of systematic reviews and meta-analyses have demonstrated that TEA was…
- Trial name
- NCT03460561
- Testing
- Thoracic epidural block (TEA), Rectus sheath block (RSB)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Egypt Cancer Institute
Surgical Site Infection
Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Postoperative Colorectal Cancer Infection in Elective Surgery
Intrabdominal antibiotic irrigation will reduce wound and intrabdominal infection.
- Trial name
- lavage (NCT01378832)
- Testing
- Intra-peritoneal antibiotic lavage
- Volunteers
- 102 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Complication, Anastomotic Leak
Prediction of Intra-abdominal Infectious Complication by Drainage Fluid Analysis
In our previous study, a nomogram model was established to predict intra-abdominal infectious complications after gastrointestinal surgery.
- Conditions
- Complication, Anastomotic Leak, Intraabdominal Infections, Inflammatory Response
- Trial name
- APPEAL-GC (NCT03862378)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University
Intraabdominal Hypertension, Abdominal Compartment Syndrome
Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients.
- Conditions
- Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
- Trial name
- NCT04669548
- Testing
- Accuryn Monitoring System
- Where
- 9 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Potrero Medical
Peritoneal Carcinomatosis, Pseudomyxoma Peritonei
Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed
The purpose of this study is to register the follow-up data of patients who, because of a peritoneal surface malignancy, will undergo cytoreductive surgery and HIPEC.
- Conditions
- Peritoneal Carcinomatosis, Pseudomyxoma Peritonei, Peritoneal Mesothelioma
- Trial name
- HIPEC (NCT01617382)
- Where
- Belgium
- Volunteers
- 125 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Abdominoplasty Surgery
Correlation Between Intra-abdominal Pressure and Diaphragmatic Mobility in Women Submitted to Abdominoplasty After Bariatric Surgery
Background: Plication of the rectus abdominis muscles leads to an increase in intra-abdominal pressure (IAP), which may negatively impact the respiratory system due to its effects on diaphragmatic mobility (DM).
- Trial name
- NCT06648694
- Testing
- Abdominoplasty surgery, Abdominoplasty
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Laparoscopic Abdominal Surgeries
Endothelial Dysfunction and Nitric Oxyde During Laparoscopic Surgery
This single-centre, pilot, prospective, randomized, open-label clinical trial evaluated the effect of intraoperative inhaled nitric oxide (iNO) on endothelial function, intestinal and renal injury biomarkers, and early clinical…
- Trial name
- ED-NOanesth (NCT07638124)
- Testing
- Inhaled nitric oxide at 40 ppm administered via the inspiratory limb of the anaesthesia ventilator circuit
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Alexander Averyanov
Sepsis, Intra-Abdominal Infections
Gelaspan vs Crystalloid Therapy in Sepsis
The goal of this randomized clinical trial is to evaluate whether balanced gelatin solution is more effective and safe than balanced crystalloid solution for perioperative fluid management in adults with sepsis undergoing…
- Trial name
- SPACES (NCT07172451)
- Testing
- Balanced Gelatin Solution, Acetate Ringer's Solution
- Where
- 9 sites in China
- Volunteers
- 318 people
- Sponsor
- Shanghai Zhongshan Hospital
Misoprostol Allergy, Oxytocin Allergy
Methods Decreasing Bleeding in Open Myomectomy
Uterine leiomyomas (fibroids or myomas) are benign, smooth muscle tumors of the human uterus. Most myomas are asymptomatic (symptomless) and are discovered incidentally during a routine pelvic examination or imaging studies and…
- Conditions
- Misoprostol Allergy, Oxytocin Allergy, Tranexamic Acid Allergy, Ethamsylate Allergy
- Trial name
- NCT05806307
- Testing
- Misoprostol, Tourniquet, Carbetocin
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Cairo University
Abdominal Compartment Syndrome
Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication
An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti…
- Trial name
- NCT06291389
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Surgical Wound Infection, Wound; Abdomen, Abdominal Wall
Surgical Site Infection Rate After Intra-Abdominal Surgery Using Negative Pressure Wound Therapy at Initial Closure
The goal of this study is to present a large single-institution experience reporting surgical site infection rates in patients who have undergone intra-abdominal surgery followed by wound closure with Negative Pressure Wound…
- Conditions
- Surgical Wound Infection, Wound; Abdomen, Abdominal Wall, Surgery
- Trial name
- NCT01924884
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins University
Intraabdominal Abscess After Procedure
Specific Bile Microorganisms Caused Intra-abdominal Abscess on Pancreaticoduodenectomy Patients: Customized Antibiotics And Antifungal Medication May Be Necessary
Background Intra-abdominal abscess (IAA) is one of the most serious surgical infectious complications on pancreaticoduodenectomy (PD) patients.
- Trial name
- NCT05011630
- Testing
- Pancreaticoduodenectomy
- Volunteers
- 539 people
- Sponsor
- National Taiwan University Hospital
Major Surgery, Intraabdominal Hypertension
Different Intra-abdominal Pressures and Optic Nerve Size
In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures.
- Conditions
- Major Surgery, Intraabdominal Hypertension, Optic Nerve Congestion
- Trial name
- NCT04556877
- Testing
- Intraabdominal pressure and optic nerve diameters
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Trakya University