Clinical trials: Intestinal Obstruction and Ileus, active
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
PIPO
Role of ACTG2 Variants in Smooth Muscle Determination and Function in Pediatric Intestinal Pseudo-obstruction.
The primary objective of this study is to describe the transcriptional impact of R178, R257, R40 or A136 variants of the ACTG2 gene on iPS differentiation mechanisms up to organoids derived from PIPO patient samples versus those…
- Trial name
- SMOOTH-PIPO (NCT06687564)
- Testing
- Biopsy
- Where
- 3 sites in France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Grenoble
Pseudo Obstruction
ACTG2/FLNA Testing Yield in Adult Idiopathic Chronic Intestinal Pseudo-Obstruction (CIPO) With Reduced/Absent Distal Esophageal Contractility
To assess the diagnostic yield of Sanger sequencing for ACTG2 and FLNA genes evaluation on blood or saliva sample in patients with idiopathic CIPO in which high-resolution esophageal manometry (HRM) shows reduced (DCI <450…
- Trial name
- CIPO_GEN (NCT07448753)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Marina Coletta
Ostomy - Ileostomy or Colostomy, Canser
The Effect of Ostomy Care Education Applied With the Teach-Back Method to Ostomy-Opened Individuals on Self-Care Power, Ostomy Adjustment, and Anxiety
The aim of this study is to examine the effect of ostomy care education-delivered to patients who have undergone ostomy surgery using the Teach-back method on patients' self-care ability, ostomy compliance, and anxiety levels.
- Conditions
- Ostomy - Ileostomy or Colostomy, Canser, Ileus, Intestinal Cancer
- Trial name
- NCT07788079
- Testing
- TEACH BACK METHOD
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Saglik Bilimleri Universitesi
Colon Cancer, Splenic Flexure Mobilization
Surgical Outcomes in Splenic Flexure Cancers: A Multicenter Comparison of Segmental vs. Extended Hemicolectomy (SPARROW Study)
SPARROW Study: Surgical Outcomes in Splenic Flexure Cancer Colonic cancers located at the splenic flexure where the transverse colon turns into the descending colon are uncommon and represent less than 10% of all colorectal…
- Conditions
- Colon Cancer, Splenic Flexure Mobilization, Right Hemicolectomy, Left Hemicolectomy
- Trial name
- SPARROW (NCT07289568)
- Testing
- Colectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Acibadem University
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Incarcerated Hernia, Appendicitis Acute
Prevention of Postoperative Hernias in Emergency Surgery
The aim of this observational study is to understand the risk factors and incidence of postoperative hernias among patients undergoing emergency surgery.
- Conditions
- Incarcerated Hernia, Appendicitis Acute, Cholecystitis, Acute, Ileus
- Trial name
- PROPHECY (NCT06815822)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Jan Kochanowski University
Acute Abdomen, Ileus
Rectus Sheath Catheters Following Midline Laparotomy
Rectus sheath catheters (RSC) are used for postoperative analgesia following midline laparotomies. Local anesthetics are applied to the posterior rectus sheath via the RSC.
- Conditions
- Acute Abdomen, Ileus, Colorectal Carcinoma
- Trial name
- NCT07099924
- Testing
- Ropivacaine 0.2%, Saline 0.9%
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Asklepios Kliniken Hamburg GmbH
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Rectal Cancer Surgery, Middle and Low Rectal Cancer
Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery
The goal of this clinical trial is to determine whether closing the pelvic floor peritoneum during laparoscopic radical resection of mid-low rectal cancer can reduce the incidence of postoperative ileus.
- Conditions
- Rectal Cancer Surgery, Middle and Low Rectal Cancer, Intestinal Obstruction, Ileus
- Trial name
- TOWER-1 (NCT07432542)
- Testing
- Pelvic floor peritoneum reconstruction
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sun Yat-sen University
Meconium Obstruction of Prematurity
Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.
The goal of this clinical trial is to study the effect of twice-daily saline enema (SE) in the treatment obstruction of prematurity (MOP) in infants with the birth weight ≤1.25kg.
- Trial name
- NCT06048614
- Testing
- Saline Enema (SE), Glycerin Suppository
- Where
- 2 sites in Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Small Bowel Obstruction, Intestinal Obstruction and Ileus
The Effect of Nasogastric Tube Placement on Complications in Patients With Small Bowel Obstruction - the SBO-TUBE Trial
Background: Small bowel obstruction (SBO) is a surgical emergency where the normal continuous bowel movements are hindered and approximately 8000-9000 patients visit the emergency department every year in Sweden due to SBO.
- Trial name
- SBO-TUBE (NCT07574515)
- Testing
- Nasogastric tube placement
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Linkoeping
Post Operative Patients
The Food Network Effect
The goal of this clinical trial is to learn if exposure to food related visual stimuli during the postoperative period can improve gastrointestinal recovery after abdominal surgery in adult patients.The main questions it aims to…
- Trial name
- NCT07618559
- Testing
- Food Related Visual Stimuli Exposure
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Casey Morehouse, DO