Clinical trials: Intervention Study
Partial-edentulism
Reconstruction of Localized Alveolar Ridge Defects
The aim of the present prospective randomized controlled study is to compare the clinical, radiological, micro-circulation, and histology of a novel, semi-thick, and conventional full-thickness mucoperiosteal flap technique…
- Trial name
- NCT05538715
- Testing
- Split-thickness group, Full-thickness group
- Where
- Hungary
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Stress
A Mixed Methods Evaluation of HPI Resilience Intervention Study
The primary objective of the Resilience Study is to determine the impact of the Corporate Athlete® Resilience product through recalibrating mindset and changing resilience supportive behavior.
- Trial name
- NCT03451240
- Testing
- Corporate Athlete® Resilience
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Health and Wellness Solutions, Inc.
Hypertension and Dyslipidemia
A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-386(2)
A Clinical Trial to evaluate the Pharmacokinetics and Tolerability of CKD-386
- Trial name
- NCT04694989
- Testing
- CKD-386, D013, D326, D337
- Where
- South Korea
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
HIV Infections
Evaluating the Safety and Immunogenicity of Stabilized CH505 TF chTrimer in Healthy, HIV-uninfected Adult Participants.
This is an open-label Phase 1 study to examine the safety and immunogenicity of the CH505 TF chTrimer vaccine with 3M-052-AF +/- Alum adjuvant in healthy adults.
- Trial name
- NCT04915768
- Testing
- CH505 TF chTrimer, 3M-05-AF, Aluminum hydroxide suspension
- Where
- 3 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Orthodontic Retainer
Comparative Assessment of Failure Rate of Fixed Lingual Retainer Between Two Types of Light Cured Resin Composite
The study will be performed on human subjects with finished orthodontic treatment to see the failure rate(detachment) of fixed lingual retainer between two types of light cure resin composite
- Trial name
- NCT05660668
- Testing
- Transbond LR, Transbond XT
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Food Addiction
Probiotic Intervention Study
The current standard of care for obesity is the optimal management of comorbid conditions such as diabetes and hyperlipidemia, and counseling on diet, weight loss, or increased physical activity programs.
- Trial name
- NCT06030362
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcohol Abuse
Effectiveness and Safety of Probiotics in Protecting Liver Function
To evaluate the effectiveness and safety of using probiotics to protect the liver function of long-term alcohol consumers
- Trial name
- NCT06607562
- Testing
- Probiotic group
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Periodontitis
Effects of Ozone Therapy as an Adjunct to Periodontal Treatment
This randomized, placebo controlled, split-mouth clinical study trial evaluates the effects of Ozone therapy on clinical and biochemical parameters. Total of 20 participants completed the study .
- Trial name
- NCT03652558
- Testing
- Ozone application with the Ozonytron XL device
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Noise-induced Hearing Loss
Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL)
This prospective study is a randomized, double-blind, placebo-controlled Phase 3 clinical trial of oral D-methionine (D-met) to reduce noise-induced hearing loss (NIHL) and tinnitus.
- Trial name
- NCT02903355
- Testing
- D-methionine
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University
Pediatric Growth Hormone Deficiency (PGHD)
A Clinical Trial to Compare Pharmacokinetics of Two Different PEG-rhGH Preparations
The purpose of this study is to compare the pharmacokinetics of the two different PEG-rhGH preparations after a single administration.
- Trial name
- NCT06135155
- Testing
- PEG-rhGH with new preparation, PEG-rhGH with present preparation
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Pharmacokinetics
Mass Balance Study of [14C]ZSP1273 in Healthy Adult Male Subjects in China
This study is a single-center, open-label, and single-dose clinical study to evaluate the mass balance, biotransformation and pharmacokinetics of [14C]ZSP1273 in healthy Chinese male participants, revealing the overall…
- Trial name
- NCT05873426
- Testing
- [14C] ZSP1273
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Alzheimer Disease
U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk
The purpose of this research study is to see if lifestyle changes can protect memory and thinking (cognition) as we age. A recent study in Finland found that a combination of physical and cognitive exercise, diet, and social…
- Trial name
- POINTER (NCT03688126)
- Testing
- Self-Guided Lifestyle Intervention, Structured Lifestyle Intervention
- Where
- 6 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Secondary Caries
Effect of Bioactive Restorative Materials on Secondary Caries Prevention
This manuscript presents a 24-month randomised clinical trial evaluating the effectiveness of bioactive restorative materials in preventing secondary caries compared with conventional composite restorations.
- Trial name
- BARM (NCT07619378)
- Testing
- Fuji IX GP Glass Ionomer Cement, Beautifil II Giomer, Cention N
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jouf University
Neck Pain
Manual Therapy Techniques on Cervical Spine and Psychological Interaction
Manual therapy (MT) techniques applied over cervical region have over both local (neck) and distant regions (elbow) in both asymptomatic and symptomatic populations.
- Trial name
- NCT02782585
- Testing
- Cervical manipulation, Cervical lateral glide, Cervical mobilisation
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Diabetes Mellitus, Insulin Hypoglycemia
Information and Communication Technology Based Centralized Clinical Trial Monitoring System for Insulin Dose Adjustment
This is a 24-week, open-label, randomized, multi-center trial conducted in three tertiary hospitals. There are three follow-up measures; at baseline, post-intervention at Week 12, and Week 24.
- Conditions
- Diabetes Mellitus, Insulin Hypoglycemia, Insulin-dependent Diabetes Mellitus
- Trial name
- ICT (NCT03112343)
- Testing
- Algorithm-based feedback messages, Personal Health Record
- Where
- South Korea
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Exercise Overtraining
Hydrogen-Infused Water for Endurance Performance, Body Hydration Biomarkers, and Health-Related Quality of Life
The study investigates the impact of 4-week hydrogen-infused water consumption on various health and performance outcomes. Conducted with healthy young adults, the trial assesses endurance performance, hydration biomarkers, and…
- Trial name
- HYDRO2EAU (NCT06788015)
- Testing
- Hydrogen-infused water
- Where
- Serbia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Sedentary Healthy Young Individuals
The Effect of Square Stepping Exercises Training on Lower Extremity
Physical activity plays an indispensable role to lead a healthy life. Square-stepping exercises (SSE) are aerobic exercises.Our study was designed to investigate the effects of square-stepping exercise training on lower-extremity…
- Trial name
- NCT04910035
- Testing
- Exercises Training
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Dental Anxiety, Dental Fear
Examining Stress Salivary Biomarkers in Pediatric Patients Undergoing Dental Procedures
Pediatric patients are susceptible to show signs of fear. One of the scenarios that have always been a source of fear is undergoing a dental procedure.
- Conditions
- Dental Anxiety, Dental Fear, Stress, Pediatric Population
- Trial name
- NCT06730425
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Sleep, Mood
A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products
This is a virtual, single-arm clinical trial that will last 12 weeks. Participants will trial three different products, each for 4 weeks.
- Conditions
- Sleep, Mood, Caffeine Withdrawal, Anxiety
- Trial name
- NCT06146517
- Testing
- Clevr Sleeptime, Clevr Matcha, Clevr Chai
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Clevr Blends
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