Clinical trials: Intervention Studies
Gingival Recession, Localized
The Efficacy of Amnion Chorion Allograft in Management of Gingival Recession.
the main goal of this clinical trial is to test the efficacy of amnion Chorion allograft in managing gingival recession. The main questions it aims to answer are: Is it effective in treating gingival recession, and how it…
- Trial name
- NCT06508476
- Testing
- Amnion Chorion membrane, connective tissue graft
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Minia University
Discoloration, Tooth
Effect of Using Shade Blocker Versus Chameleon Effect of Two Single Shade of Resin Composite in Class IV Restorations
Aim of this study will be conducted to compare the shade matching and clinical performance of shade blocker versus chameleon effect of two single-shade of universal resin composite in class IV restorations over 1 year evaluation…
- Trial name
- NCT05315518
- Testing
- single-shade universal resin composite (omnichroma) with blocker( omnichroma blocker)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neurotoxicity
Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer Patients
The purpose of this study is to determine whether monosialoganglioside are effective in the prevention of neurotoxicity induced by albumin-bound paclitaxel chemotherapy in lung cancer patients, and improve the quality of life of…
- Trial name
- NCT02500810
- Testing
- monosialoganglioside
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Peking University Cancer Hospital & Institute
DMMR Cancer, MSI-H
Registry Study in MSI/dMMR Solid Tumors
This study is a multi-center, non-interventional, prospective clinical observational study, aiming to evaluate the effectiveness and safety of subsequent treatment in dMMR/MSI solid tumor patients who have never received ICIs…
- Conditions
- DMMR Cancer, MSI-H, Solid Tumor
- Trial name
- NCT06004713
- Where
- 10 sites in China
- Volunteers
- 190 people
- Sponsor
- Peking University Cancer Hospital & Institute
Cancer-related Problem/Condition
Combined Fluoroscopy and CT Guided Radiofrequency Ablation of Thoracic Dorsal Root Ganglia in Severe Thoracic Pain
In the current study, extra-guidance other than conventional fluoroscopy - will be integrated to improve the success of the transforaminal approach to the thoracic dorsal root ganglia (DRG).
- Trial name
- NCT03533413
- Testing
- combined CT-fluroscopy, standard fluroscopy
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- National Cancer Institute, Egypt
Dermatitis, Atopic, Eczema
A Study of Lebrikizumab in Combination With Topical Corticosteroids in Patients With Atopic Dermatitis (AD) That Are Not Adequately Controlled With or Are Non-eligible for Cyclosporine
The main purpose of this study is to evaluate the efficacy of lebrikizumab compared with placebo in participants not adequately controlled with cyclosporine or for whom cyclosporine is not medically advisable up to Week 16.
- Trial name
- ADvantage (NCT05149313)
- Testing
- Lebrikizumab
- Where
- 48 sites in Austria, Belgium and 6 more
- Volunteers
- 331 people
- Sponsor
- Almirall, S.A.
Stenosis of Arteriovenous Dialysis Fistula
SUPER-DIALYSIS-Study: Supera Stent Interventions in Juxta-anastomotic (re)Stenosis
The purpose of this exploratory study is to evaluate safety and effectiveness of treatment of juxta-anastomotic (re)stenosis with SUPERA stent by improving hemodynamic situation through obtuse shaping of the anastomosis.
- Trial name
- NCT05232760
- Testing
- Supera™ Peripheral Stent System
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Klinikum Arnsberg
Anxiety Disorders, Depression
Emotional Impact of the Way Conducting Cancer Patients to the Surgical Center
Cancer is an extremely aggressive disease, anxiety and depression are consequences some patients may develop from diagnosis continuing during treatment. A measures control of the cancer is surgery for removal tumor.
- Trial name
- NCT03576482
- Testing
- Transport on foot
- Where
- Brazil
- Volunteers
- 176 people
- Sponsor
- Barretos Cancer Hospital
Nursing Education, Immersive Virtual Reality
Immersive Virtual Reality Training for Phlebotomy Skills in Nursing Students
This randomized controlled trial aims to evaluate the effect of immersive virtual reality (VR) training on nursing students' learning outcomes in phlebotomy skills.
- Conditions
- Nursing Education, Immersive Virtual Reality, Phlebotomy, Part-Task Trainer Simulation
- Trial name
- NCT07673224
- Testing
- Immersive Virtual Reality Training, Part-Task Trainer Simulation Training
- Where
- Palestinian Territories
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Diabetic Neuropathy, Painful
Study to Evaluate MK-6096 in the Treatment of Painful Diabetic Neuropathy (PDN) in Adults (MK-6096-021)
The purpose of this study is to evaluate the safety and effectiveness of MK-6096 in the treatment of painful diabetic neuropathy (PDN) in adults.
- Trial name
- NCT01564459
- Testing
- MK-6096
- Volunteers
- 170 people
- Sponsor
- Merck Sharp & Dohme LLC
Implantable Cardioverter-defibrillators (ICDs)
Nursing Intervention Guided by an ICD Nursing Guideline
This study aimed to evaluate evidence-based nursing intervention guided by an ICD nursing guideline on self-efficacy, device acceptance, satisfaction with nursing care, and outcome expectations among ICD candidates during the…
- Trial name
- NCT07449559
- Testing
- nursing care with an evidence-based ICD nursing guideline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Full-frequency Sudden Hearing Loss
Sudden Hearing Loss Multi-center Clinical Trial
The incidence of sudden hearing loss is rising obviously resent year, Glucocorticoids have obtained obvious effect in the treatment of sudden deafness.
- Trial name
- NCT02026479
- Testing
- Dexamethasone Phosphate, Ginaton
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
Neuroblastoma
Oral Liquid 13-cis-retinoic Acid (13-CRA)
An open label, randomised, multiple dose, cross-over relative bioavailability and pharmacokinetics trial of a novel oral liquid and capsule formulations of 13-CRA administered to patients from 0 months - < 21 years.
- Trial name
- My-CRA (NCT03291080)
- Testing
- Liquid 13-Cis Retinoic Acid, Extracted capsules 13-CRA
- Where
- 10 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nova Laboratories Limited
Vasoplegia, Cardiac Surgery
Low Dose Corticosteroid Infusion in Vasoplegia After Cardiac Surgery (CORTIVAS-CS)
Vasoplegia is an important determinant for adverse postoperative outcome and is observerd in 5% to 54% of patients undergoing cardiac surgery using cardiopulmonary bypass (CPB).
- Trial name
- CORTIVAS-CS (NCT04301479)
- Testing
- hydrocortisone sodium succinate, Saline
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Instituto do Coracao
Emergency Patient Transported by Ambulance
Evaluation of Effectiveness for Connected Network for EMS Comprehensive Technical-support Using Artificial Intelligence (CONNECT-AI) System by Community Intervention
This study aims to verify the effectiveness of the connected network for EMS comprehensive technical-support using artificial intelligence (CONNECT-AI) system through demonstration in the local community.
- Trial name
- NCT04829279
- Testing
- CONNECT AI system group
- Where
- South Korea
- Volunteers
- 15,392 people
- Sponsor
- Yonsei University
Premixed, Sequential
Premixed vs Sequential Injections of Lidocaine and Bupivacaine for Supraclavicular Brachial Plexus Block in Patients Undergoing Arteriovenous Fistula Creation
This study aims to compare premixed and sequential injections of lidocaine and bupivacaine for supraclavicular brachial plexus block in patients undergoing arteriovenous fistula creation.
- Conditions
- Premixed, Sequential, Lidocaine, Bupivacaine
- Trial name
- NCT06570096
- Testing
- Lidocaine 2% then bupivacaine 0.5%, Lidocaine 2% and bupivacaine 0.5%
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
A Non-interventional Study of Participants With BPDCN Treated With Chemotherapy
The main goal of this study is to investigate the effectiveness and safety of chemotherapy agents in the treatment of participants with BPDCN and to provide comparator arm data to the prospective ELZONRIS registry study…
- Trial name
- NCT07785180
- Testing
- Chemotherapy
- Where
- 67 sites in Denmark, France and 9 more
- Volunteers
- 140 people
- Sponsor
- Stemline Therapeutics, Inc.
Healthy Diet
Intervention Study on Iodine and Molybdenum Biofortification Vegetables ( Nutri-I-Mo )
The aim of the project is to study the influence of Lettuce crop enriched with Molybdenum and lettuce enriched with Iodine administrated at the same time on healthy population in order to assess influence on hematological…
- Trial name
- Nutr-I-Mo (NCT04984746)
- Testing
- No Intervention: (control group), Experimental: intervention group
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Stroke
Managing Aftercare for Stroke (MAS): MAS-II - A Longitudinal Complex-interventional Study in Post-rehabilitation Stroke Patients
After discharge from hospital, the current healthcare system in Germany allows considerable flexibility (therefore complexity) of patient access and mobility between multiple care providers in the community setting.
- Trial name
- NCT03097146
- Testing
- comprehensive multidisciplinary stroke care
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- Charite University, Berlin, Germany
Covid-19
Clinical Application of Methylene Blue for Treatment of Covid-19 Patients
The severe acute respiratory syndrome caused by COVID-19 is now a global catastrophic event. Currently there is no approved drug or vaccine for the disease.
- Trial name
- Covid-19 (NCT04370288)
- Testing
- MCN (Methylene blue, vitamin C, N-acetyl cysteine)
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
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