Clinical trials: Internal Derangement
Internal Derangement
Intra-articular Injection of Medications in TMJ After Arthrocentsis
The aim of this study: to evaluate the injection of hyaluronic acid and corticosteroids mixture leads to better clinical outcomes in terms of improve maximum mouth opening and reduce pain compared with hyaluronic acid and prp…
- Trial name
- NCT07598253
- Testing
- Arthrocentesis with ringer solution
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Internal Derangement of Hip, Acetabular Labrum Tear
Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain
The goal of the study is to evaluate via a prospective, blinded, randomized clinical trial, whether ultrasound-guided single femoral and lateral femoral cutaneous nerve blocks with ropivacaine 0.5% with epinephrine (1:200,000) as…
- Trial name
- NCT01997567
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Rush University Medical Center
Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears
Added Diagnostic Value of CT Arthrography to MR Arthrography in Wrist Internal Derangement
The wrist is a complex joint made up of small bones, cartilage, and stabilizing ligaments, including the triangular fibrocartilage complex (TFCC) and intrinsic carpal ligaments.
- Conditions
- Wrist Internal Derangement, Triangular Fibrocartilage Complex Tears, Scapholunate Ligament Tears, Lunotriquetral Ligament Tears
- Trial name
- NCT07826208
- Testing
- Combined CT Arthrography and MR Arthrography
- Volunteers
- 60 people
- Sponsor
- Assiut University
TMJ Disc Disorder
Assessment of Concentric Needle Technique in Temporomandibular Joint (TMJ) Internal Derangement.
The aim of the study is to evaluate the effectivenes of using two concentric needles in comaprsion with the normal traditional two distant needles.
- Trial name
- NCT05510336
- Testing
- Arthrocentesis
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
TMJ Disc Disorder
Clinical Evaluation of Stabilizing Splint (Michigan-type Occlusal Splint) Versus Anterior Repositioning Splint .
To evaluate the effectiveness of Michigan-type occlusal splint and anterior repositioning splint in patients with temporomandibular joint anterior disc displacement with reduction.
- Trial name
- NCT02960048
- Testing
- Stabilizing splint, Anterior repositioning splint
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Joint Disorders
Evaluation of Anterior Repositioning Guided Splint Combined With or Without I Platelet-rich Fibrin
The study aims to evaluate clinically and radiographically the effectiveness of arthrocentesis and injection of I-PRF with wearing ARS in comparison to arthrocentesis and ARS only.
- Trial name
- NCT06132802
- Testing
- Patients who received treatment involving ARS and arthrocentesis only, Patients who received treatment involving ARS, arthrocentesis, and an I-PRF injection
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mahmoud Mohammed Mahmoud Nasef
Anterior Disk Displacement TMJ
Ultrasound-guided vs Conventional Intraarticular Injection of Hyaluronic Acid for Management of Temporomandibular Joint Internal Derangement
The aim of the study will be to evaluate the clinical efficacy of using ultrasound guidance during intra-articular injection of hyaluronic acid in the management of patients with TMJ internal derangement.
- Trial name
- RCT (NCT07266714)
- Testing
- Ultrasound guided injection with hyaluronic acid, Conventional
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Muhannad
Temporomandibular Disorder
Computer Guided Visco Supplementation in the Management of Internal Derangement of Temporomandibular Joint
Background: The intra-articular injection is considered the first line of minimally invasive treatment in TMJ-ID patients who do not respond to conservative treatment.
- Trial name
- NCT06667791
- Testing
- Computer guided sodium hyaluronate injections, conventional sodiumhyaluronate injections
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Hams Hamed Abdelrahman
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
TMJ Disorder
MESNA Injection for TMJ Internal Derangement
The pathogenesis of temporomandibular disorders focusing on the biochemistry of the synovial fluid in various stages of temporomandibular joint disease.
- Trial name
- NCT05882604
- Testing
- Mesna Injection, Arthrocentesis with ringer solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Temporomandibular Joint Internal Derangement, Temporomandibular Joint Disorders
Arthrocentesis-PRF Versus Botulinum Toxin for Management of ADDwR
Temporomandibular joint (TMJ) internal derangement is a common cause of temporomandibular disorders and is often associated with pain, restricted mandibular movement, joint sounds, and functional limitations during mastication…
- Conditions
- Temporomandibular Joint Internal Derangement, Temporomandibular Joint Disorders, Temporomandibular Disorders (TMD), TMJ Pain
- Trial name
- NCT07385742
- Testing
- Injectable Platelet-Rich Fibrin (I-PRF) Injection, Botulinum Toxin Type A (BOTOX) Injection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Temporomandibular Joint Internal Derangement
Effect of Intraarticular Injection of Tenoxicam and Hyaluronic Acid Versus Platelet-Rich Plasma and Hyaluronic Acid in Temporomandibular Joint Internal Derangement
To compare the effect of intraarticular injection of Tenoxicam and Hyaluronic acid Versus Platelet-rich plasma and Hyaluronic acid in the management of patients with TMJ internal derangement with reduction.
- Trial name
- NCT06572904
- Testing
- Tenoxicam Injectable Product, Hyaluronic Acid 20 MG/1 ML Injection Gel/Jelly
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
TMJ Internal Derangement
Correlation Between MRI Findings and Clinical Improvement Following TMJ Injection With Hyaluronic Acid and Platelet-Rich Plasma
Temporomandibular joint (TMJ) disorders can cause jaw pain, clicking sounds, and difficulty opening the mouth, affecting daily activities such as eating and speaking.
- Trial name
- MRI TMJ (NCT07750522)
- Testing
- intra-articular Injection of Hyaluronic Acid Combined with Platelet-Rich Plasma
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
TMJ Internal Derangement, TMJ - Dislocation of Temporomandibular Joint
Extracapsular Supradiscal Subperiosteal Surgical Procedure for Temporomandibular Joint Internal Derangement Correction: Novel Technique
This study aims to evaluate the efficacy of the ESS technique in correcting TMJ internal derangement, with a focus on functional outcomes and patient satisfaction.
- Conditions
- TMJ Internal Derangement, TMJ - Dislocation of Temporomandibular Joint, TMJ - Oral &Maxillofacial Surgery
- Trial name
- NCT06867744
- Testing
- Extracapsular Supradiscal Subperiosteal Surgical Procedure for Temporomandibular Joint Internal Derangement Correction
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Mohamed Moawed Ibrahim Ghoneim, PhD
Temporomandibular Joint Dysfunction, TMD
Effects of Core Strengthening Exercises for Treating TMD
Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education.
- Conditions
- Temporomandibular Joint Dysfunction, TMD, TMJ Internal Derangement, Myofascial Pain
- Trial name
- NCT07226505
- Testing
- Experimental: Group 1: Core Strengthening, Group 2: Standard TMD PT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
Temporomandibular Joint Internal Derangement
Efficacy of Intra-Articular Hyaluronic Acid Combination Injections for Temporomandibular Joint Internal Derangement: A Clinical and MRI Based Randomized Trial
This randomized controlled clinical trial aims to compare the clinical and magnetic resonance imaging (MRI) outcomes of three intra-articular injection protocols for the treatment of temporomandibular joint (TMJ) internal…
- Trial name
- MRI (NCT07750483)
- Testing
- intraarticular injection in TMJ
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
TMJ Disc Disorder
Comparison Between Different Concentrations of Ozone Gas as an Intra-articular Injection for Treatment of Internal Derangement of Tempromandibular Joint
The intra-articular injection is considered the first line of minimally invasive treatment of joint disease as it has an analgesic, antimicrobial effect and an immune system stimulating action as it is one of the most powerful…
- Trial name
- NCT07523451
- Testing
- Patients will be treated with 2ml ozone oxygen mixture with concentration 6 micron/ml, Patients will be treated with 2ml ozone oxygen mixture with concentration 12 micron/ml
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
TMJ Disc Disorder
Chitosan-Hyaluronate Gel Mixture Vs Hyaluronic for Internal Derangement
This study is designed to assess the impact of injecting sodium hyaluronic acid versus a chitosan-hyaluronate hybrid gel into the upper compartment of the temporomandibular joint (TMJ) as a treatment for anterior disc…
- Trial name
- TMJ (NCT06426199)
- Testing
- Chitosan-Hyaluronate Gel Mixture, Hyaluronic Acid
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Temporomandibular Joint Disc Displacement
Evaluation of the Efficacy of Injectable Platelet-Rich Fibrin Mixed With Hyaluronic Acid in Treatment of Temporomandibular Joint Internal Derangement
we inject I-PRF and Hyaluronic Acid inside the human TMJ with internal derangement after arthrocentesis, and follow-up is made to evaluate the effect of this treatment.
- Trial name
- NCT07373730
- Testing
- Hyalgan 20 mg in 2 ML Prefilled Syringe, I-PRF
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Temporomandibular Joint Internal Derangement
Clinical Effectiveness of Combined Arthrocentesis With Intra-articular Injection of Meloxicam in Treatment of Temporomandibular Joint Internal Derangement
This randomized controlled clinical study is designed to evaluate the clinical effectiveness of combining temporomandibular joint (TMJ) arthrocentesis with a single intra-articular injection of meloxicam in patients suffering…
- Trial name
- NCT07743684
- Testing
- Arthrocentesis with ringer lactate solution and meloxicam injection, Arthrocentesis with ringer lactate solution
- Where
- Iraq
- Volunteers
- 50 people
- Sponsor
- Hussein Mohammed Ridha