Clinical trials: Intermittent Positive-Pressure Ventilation
Aortic Regurgitation Disease, Aortic Insufficiency
Impact of Anesthesia, Positive Pressure Ventilation and Modality of Imaging on the Echocardiographic Assessment of the Severity of Aortic Regurgitation
The goal of this observational study is to assess the impact of imaging modality (trans-thoracic echo (TTE) vs trans-esophageal echo (TEE)), anesthesia and positive pressure ventilation on the grading of aortic insufficiency.
- Trial name
- NCT06835946
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University of Liege
Intensive Care
Bedside Measurement of Ventilation With or Without a One-way Valve During Lung Lavage
Surveillance of the lungs for bacteria is routinely undertaken in artificially ventilated patients as these individuals are at high risk of developing pneumonia.
- Trial name
- NCT01143961
- Testing
- CSC100 - Verso airway access adapter CareFusion
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cardiff and Vale University Health Board
Respiratory Distress Syndrome
Nasal Intermittent Positive Pressure Ventilation In Newborn Infants With Respiratory Distress Syndrome
The submitted trial is the first prospective, randomized trial comparing nasal intermittent positive pressure ventilation(NIPPV) vs nCPAP in newborn infants with respiratory distress syndrome.
- Trial name
- NCT00780624
- Testing
- NIPPV
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Third Military Medical University
Mechanical Ventilation, Positive End-Expiratory Pressure
Influence of Inspiratory Pause on Ventilatory Efficiency in Robotic Surgery. A Prospective Paired Study.
The investigators aim to determine if the modification of the end inspiratory pause (EIP) during mechanical ventilation adds benefit when applied to patients undergoing robotic surgery and who are ventilated under an…
- Conditions
- Mechanical Ventilation, Positive End-Expiratory Pressure, Anesthesia
- Trial name
- NCT05514366
- Testing
- Modifying EIP under a tOLA before pneumoperitoneum, Modifying EIP under a tOLA with pneumoperitoneum, Atelectasis test
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Mechanical Ventilation
Mechanical Ventilation in Multiple Fracture Ribs
Chest trauma is the most common injury in the emergency trauma and rib fractures is the most common trauma in chest trauma. Severe rib fractures can cause paradoxical respiration and mediastinal swing, which has large effects on…
- Trial name
- NCT03314701
- Testing
- Biphasic Intermittent Positive Airway Pressure (BIPAP), Airway Pressure Release Ventilation (APRV)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea, Spinal Cord Injuries
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
Mild intermittent hypoxia (IH) initiates sustained increases in chest wall and upper airway muscle activity in humans. This sustained increase is a form of respiratory plasticity known as long-term facilitation (LTF).
- Trial name
- NCT03736382
- Testing
- Mild intermittent hypoxia, Continuous positive airway pressure (CPAP)
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Wayne State University
Intermittent Positive-Pressure Ventilation, High-Frequency Jet Ventilation
High Frequency Jet Ventilation Versus Conventional Positive Pressure Ventilation for EBUS
Endobronchial ultrasound (EBUS) is frequently used in pneumology for diagnostic procedures like mediastinal biopsies. This procedure is usually done under general anesthesia.
- Conditions
- Intermittent Positive-Pressure Ventilation, High-Frequency Jet Ventilation, Ultrasonography, Interventional
- Trial name
- NCT06537388
- Testing
- Ventilation type
- Where
- Belgium
- Volunteers
- 428 people
- Sponsor
- Erasme University Hospital
Respiratory Insufficiency
Nasal High Frequency Oscillatory Versus Nasal Intermittent Positive Pressure Ventilation in Neonate After Extubation
To evaluate the efficacy and safety of nasal high frequency oscillatory ventilation(NHFOV) in preterms with respiratory disease syndrome(RDS) after extubation.
- Trial name
- NCT02543125
- Testing
- NIPPV, NHFOV
- Volunteers
- 75 people
- Sponsor
- Gao WeiWei
Chronic Respiratory Failure
Prognosis in Patients With Chronic Respiratory Failure Receiving Domiciliary Noninvasive Positive Pressure Ventilation (NPPV)
The purposes of the present study are (1) to analyze baseline patient characteristics cross-sectionally, (2) to analyze the prognosis and its predictive factors, and (3) to examine longitudinal clinical course in patients with…
- Trial name
- NCT00905476
- Where
- 11 sites in Japan
- Volunteers
- 56 people
- Sponsor
- Kyoto University, Graduate School of Medicine
COPD, Non Invasive Ventilation
Prospective Cohort of Respiratory Insufficiency Outcome
The Respiratory Insufficiency Outcome (RIO) project consists in a french multicenter prospective cohort of patients with chronic obstructive pulmonary disease (COPD) undergoing domiciliary noninvasive positive pressure…
- Trial name
- RIO (NCT01192451)
- Where
- 4 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Respiration Failure, Cardio Vascular Disease
COMPARE-VENT Feasibility Pilot Study
Cardiac disease complicated by respiratory insufficiency comprises the most frequent indication for cardiac intensive care unit (CICU) admission, with nearly one-third patients requiring advanced respiratory support and over 20%…
- Conditions
- Respiration Failure, Cardio Vascular Disease, Cardiogenic Pulmonary Oedema, Critical Illness
- Trial name
- NCT07656259
- Testing
- Volume Controlled Mode, Pressure Controlled Mode
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
Gastric Insufflation
Gastric Insufflation During Positive Pressure Ventilation
Effect of peak inspiratory pressure on the gastric insufflation is evaluated using ultrasonography during face mask ventilation in obese adults.
- Trial name
- NCT04964882
- Testing
- ultrasound examination of air insufflation in the upper esophageal region and stomach
- Volunteers
- 78 people
- Sponsor
- SMG-SNU Boramae Medical Center
COPD
Analyse the Correlation Between sEMG and EMGdi
The most significant pathophysiology change of COPD patients is persistent incompletely reversible airflow obstruction and increased lung volume. As a result, the work of breathing(WB) and neural respiratory drive (NRD)increased.
- Trial name
- NCT03268616
- Testing
- inspiratory threshold load device and NPPV
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Postoperative Pulmonary Complications (PPCs)
Perioperative Prophylactic Positive Pressure Ventilation Reduces Postoperative Pulmonary Complications.
The incidence of postoperative pulmonary complications (PPCs) ranges from 5% to 33%. PPCs significantly prolong hospital stay, increase the economic burden, and are associated with postoperative mortality at 30 days and 1 year.
- Trial name
- NCT07461285
- Testing
- Conventional Ventilation, Perioperative positive pressure ventilation
- Volunteers
- 206 people
- Sponsor
- Jun Zhang
Status Asthmaticus
Non Invasive Positive Pressure Ventilation in Status Asthmaticus
Status Asthmaticus is recognized as a common cause of morbidity in children in the United States (CDC). In recent years, hospitalization rates have reached an all time high.
- Trial name
- NCT01403428
- Testing
- Noninvasive positive pressure ventilation
- Where
- United States
- Sponsor
- Southern Illinois University
Respiratory Failure
Lung Volume Change Between Noninvasive Positive Pressure Ventilation by Nasal Pillow and High Flow Nasal Cannula
The difference of lung volume change will be monitored by electrical impedance tomography before and after use of noninvasive positive pressure ventilation by nasal pillow and high flow nasal cannula in post-extubation patients.
- Trial name
- NCT02292992
- Testing
- Nasal Pillow CPAP
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Mackay Memorial Hospital
Apnea, Infant, Premature
Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Very premature infants uniformly do not have mature functioning lungs to breathe well nor mature regulation mechanisms to breathe regularly. Assistance with a mechanical respirator is common.
- Conditions
- Apnea, Infant, Premature, Bronchopulmonary Dysplasia
- Trial name
- NCT00188968
- Testing
- Nasal Continuous Positive Airway Pressure, Synchronized Nasal Positive Pressure Ventilation
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Respiratory Distress Syndrome, Newborn
Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory Distress
Title of Study: A Prospective, Randomized, Multicenter Trial Comparing Synchronized Intermittent Mandatory Ventilation (SIMV) vs.
- Trial name
- NCT00486850
- Testing
- Extubation to Nasal IPPV
- Where
- 4 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Southern California
Premature Birth, Ventilator Lung; Newborn
sNIPPV Versus NIV-NAVA in Extremely Premature Infants
The aim of this study is to demonstrate a significant decrease in asynchrony with NIV-NAVA using the Servo n ventilator (Getinge, Sweden), as compared to abdominal triggered (Graseby capsule) synchronized nasal intermittent…
- Trial name
- EASYNNEO (NCT04068558)
- Testing
- VNI-NAVA/sNIPPV, sNIPPV/VNI-NAVA
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Patients With Acute Hypoxemic Respiratory Failure
Wean Early With HFNCO vs NPPV in Patients With AHRF
The main purpose of the present study is to verify whether, as compared with conventional weaning, early weaning with high-flow nasal cannula oxygenation or noninvasive positive pressure ventilation may more effective in…
- Trial name
- NCT03171935
- Testing
- High-Flow Nasal Cannula Oxygenation, Noninvasive Positive Pressure Ventilation, Conventional weaning
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Beijing Chao Yang Hospital