Clinical trials: Intermittent Hypoxemia
Intermittent Hypoxemia, Apnea of Prematurity
Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm Infants
In this randomized crossover trial, preterm infants with intermittent hypoxemia and need for supplemental oxygen will be randomized to either Sequence of two different oxygen target ranges (low: 85-89%; high: 91-95%) for a total…
- Trial name
- NCT02743988
- Testing
- Oxygen
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Ulm
Preterm, Apnea of Prematurity
Efficacy of PIMUN by Reducing Intermittent Hypoxia Events
The goal of this clinical trial is to learn if the use of PIMUN(medical device) works to reduce the intermittent hypoxemia of 24-34 weeks of birth gestational age babies. . It will also learn about the safety of the use of PIMUN.
- Conditions
- Preterm, Apnea of Prematurity, Hypoxemia
- Trial name
- NCT07396103
- Testing
- Brain NIRS, Polysomnogram, Reactive oxydative species
- Where
- 2 sites in Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Hypoxemia, Pneumonia, Viral
Nitric Oxide Therapy for COVID-19 Patients With Oxygen Requirement
Preliminary data support the effect of Nitric Oxide (NO) on improving the oxygenation in mechanically ventilated patients and spontaneously breathing patients with COVID-19.
- Conditions
- Hypoxemia, Pneumonia, Viral, Coronavirus Infection
- Trial name
- NICOR (NCT04476992)
- Testing
- Nitric Oxide-Sessions, Nitric Oxide-Continuous and Sessions
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Premature Birth, Asthma in Children
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental…
- Conditions
- Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
- Trial name
- NCT05336890
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Intermittent Hypoxemia, Acute Kidney Injury
Intermittent Hypoxemia and Acute Kidney Injury Study (IHAKI Study)
This pilot study aims at investigating the relationship between intermittent hypoxemia (IH) and acute kidney injury (AKI) in preterm infants.
- Conditions
- Intermittent Hypoxemia, Acute Kidney Injury, Preterm Infant
- Trial name
- IHAKI (NCT02837276)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Elie G. Abu Jawdeh, MD
Apnea of Prematurity, Intermittent Hypoxemia
Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover Trial
The goal of this clinical trial is to learn if a chin strap helps reduce low oxygen episodes in premature babies receiving CPAP or NIPPV (breathing support through the nose).
- Conditions
- Apnea of Prematurity, Intermittent Hypoxemia, Bronchopulmonary Dysplasia of Newborn
- Trial name
- STRAP (NCT07895654)
- Testing
- Chinstrap
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Apnea of Prematurity, Intermittent Hypoxemia
The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm Infants
The aim of this proposal is to characterize the acute effect of early postnatal sound exposure on neuronal maturation of the respiratory control regions of the brain in preterm infants.
- Conditions
- Apnea of Prematurity, Intermittent Hypoxemia, Bradycardia
- Trial name
- NCT05298748
- Testing
- Womb sound recordings
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Case Western Reserve University
Chronic Obstructive Pulmonary Disease (COPD)
Intermittent Hypoxemia, Lung Function Decline, Morbidity, and Mortality in COPD (PROSA Study).
This study aims to analyze if patients with chronic obstructive lung disease who experience a decline of blood oxygen saturation during physical exercise have a disease course different from that of COPD patients who do not…
- Trial name
- PROSA (NCT06265623)
- Testing
- No active intervention, but observational follow-up
- Where
- Germany
- Volunteers
- 148 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hypoxemia
Influence of Intermittent Hypoxia on Glycemic Control
The aim of this research project is to determine the effect of intermittent hypoxia on glucose uptake in response to an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2…
- Trial name
- NCT06490900
- Testing
- Intermittent hypoxia, Intermittent normoxia
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Hypoxemia
Effects of Acute Intermittent Hypoxia on Brain Function Imaging and Systemic Inflammation
Effects of acute intermittent hypoxia on brain function imaging and systemic inflammation Patients with obstructive sleep apnea (OSAS) may have neurological cognitive impairment. The reason is not clear.
- Trial name
- NCT03453697
- Testing
- acute intermittent hypoxia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine