Clinical trials: Intergenerational Trauma
Family Relations, Psychological Trauma
Multifamily Healing Spaces for Family Resilience in Rwanda
This cluster-randomized waitlist-control trial evaluated Multifamily Healing Spaces (MFHS), a culturally adapted behavioral family intervention for genocide-affected communities in Rwanda.
- Conditions
- Family Relations, Psychological Trauma, Stress Disorders, Post-Traumatic, Parent-Child Relation
- Trial name
- MFHS-CRT (NCT07621705)
- Testing
- Multifamily Healing Spaces
- Where
- 5 sites in Rwanda
- Volunteers
- 319 people
- Sponsor
- Alexandros Lordos, PhD
Depression, Grief
Iwankapiya-Healing: Historical Trauma Practice and Group IPT for American Indians
This study will pilot an intervention that combines group Interpersonal Psychotherapy (IPT), an empirically-supported treatment, and the Historical Trauma and Unresolved Grief Intervention (HTUG), a Tribal Best Practice for…
- Conditions
- Depression, Grief, PTSD, Interpersonal Relations
- Trial name
- HTUG-IPT (NCT02124694)
- Testing
- HTUG
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of New Mexico
Mood Lability, PTSD
FamilyLive Feasibility and Effectiveness Study
Children who have been exposed to trauma (defined as physical, sexual or emotional abuse, neglect, exposure to life threatening events, domestic and community violence, parental mental health disorders, substance abuse, and/or…
- Conditions
- Mood Lability, PTSD, Anxiety
- Trial name
- NCT01524185
- Testing
- FamilyLive, Standard Mental Health Treatment
- Where
- United States
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Anxiety, Trauma
Intergenerational Transmission of Terror
Our aim is examine avenues by which mothers can transmit their trauma to their children.
- Conditions
- Anxiety, Trauma, Stress Disorders
- Trial name
- NCT00320437
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma
FMBI With War-affected Families
This study has two central research questions: 1) Is implementing a family mindfulness-based intervention with war-affected immigrant families through community based participatory research methods feasible?; and 2) Does the…
- Conditions
- Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma, War-Related Trauma
- Trial name
- NCT05241314
- Testing
- Learning to BREATHE, After Deployment Adaptive Parenting Tools (ADAPT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Psychiatric Diagnosis, Schizophrenia Disorders
The Key to Integrated Trauma Treatment in Psychosis Trial
Schizophrenia spectrum disorders (SSDs) have a significant trauma etiology: trauma has been reported in 65 - 80% in this patient group and have a negative impact on prognosis.
- Conditions
- Psychiatric Diagnosis, Schizophrenia Disorders, Psychological Trauma, Historical
- Trial name
- KIT (NCT06608706)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) for psychosis
- Where
- 11 sites in Norway
- Volunteers
- 187 people
- Sponsor
- Haukeland University Hospital
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Child Development, Early Child Development
Intergenerational Risk and Resilience of Rohingya in Displacement
The iRRRd study is an ongoing prospective longitudinal prenatal birth cohort study based in Cox's Bazar, Bangladesh. Between February 2023 and March 2024, 2,888 pregnant women were enrolled (approximately 80% Rohingya refugees…
- Conditions
- Child Development, Early Child Development, Mental Health, PTSD - Post Traumatic Stress Disorder
- Trial name
- iRRRd (NCT07758283)
- Where
- Bangladesh
- Volunteers
- 2,200 people
- Sponsor
- New York University
Inflammation, Mental Health Wellness 1
Health Effects of Traditional Indigenous Chokeberry
American Indian populations continue to suffer disproportionately from health problems including such nutrition-related chronic diseases as diabetes and heart disease.
- Conditions
- Inflammation, Mental Health Wellness 1, Oxidative Stress
- Trial name
- NCT05410327
- Testing
- Chokeberry (Aronia melanocarpa) juice
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of North Dakota
Intergenerational Trauma
Child Cognitive-Affective Resilience Following 13-11 Event : A Pluridisciplinary Study of Intergenerational Transmission of a Traumatic Event
CARE 13-11 study explores the transmission of trauma within families. Exposure to a traumatic event can have an impact on those directly exposed, but also on their family.
- Trial name
- CARE 13-11 (NCT07203443)
- Testing
- MRI, Psychological assessment, Cognitive assessment
- Where
- France
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Anxiety Disorders, Anxiety State
Intergenerational Study of War-Affected Youth
War-related violence is a leading driver of mental disorders and illness affecting children in low- and middle-income countries (LMICs).
- Conditions
- Anxiety Disorders, Anxiety State, Depressive Disorder, Mood Disorders
- Trial name
- ISWAY (NCT06440460)
- Where
- Sierra Leone
- Volunteers
- 804 people
- Sponsor
- Boston College
Stress, Psychological, Stress Disorders, Traumatic
Intergenerational Transmission of Traumatic Stress
Millions of U.S. parents have experienced trauma, putting them at risk for maladaptive parenting practices, which then confer vulnerabilities to their children.
- Conditions
- Stress, Psychological, Stress Disorders, Traumatic, Emotion Regulation, Behavior, Child
- Trial name
- NCT05264415
- Testing
- Families OverComing Under Stress (FOCUS) for Early Childhood (FOCUS-EC), Parenting Education Website
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
Psychological Trauma, Historical, Nutrition
Nutrition for Trauma Community Survey
The survey will help investigators learn everything about how people view and respond to trauma from a holistic perspective through body (nutrition), mind (mental health rejuvenation and renewal), and spirit (faith-based) lens.
- Conditions
- Psychological Trauma, Historical, Nutrition, PTSD - Post Traumatic Stress Disorder
- Trial name
- N4T (NCT06864637)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- True Paleo Inc.
Intimate Partner Violence (IPV), Psychological Well Being
Yoga for Black and Brown Women Who Have Experienced Abuse From an Intimate Partner
The goal of this clinical trial is to determine if a culturally tailored and trauma-informed yoga (CT-TIY) program improves the overall well-being of Black and Brown women who have experienced IPV.
- Conditions
- Intimate Partner Violence (IPV), Psychological Well Being, Psychological Trauma, Historical
- Trial name
- SOAR (NCT07546266)
- Testing
- Culturally-Tailored, Trauma-Informed Yoga (CT-TIY), Enhanced Care as Usual (ECU)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Akron
Psychological Trauma, Historical, Discrimination, Racial
The Social Regulation of Threat-related Vigilance and Arousal
This study will examine the effects of social support on threat vigilance and arousal using eye tracking. We will also test the moderating effects of trauma and discrimination history.
- Conditions
- Psychological Trauma, Historical, Discrimination, Racial, Emotion Regulation, Social Interaction
- Trial name
- NCT05558527
- Testing
- social support
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Stress Disorders, Post-Traumatic, Depression
Resettled Refugee Families for Healing
The goal of this type I hybrid effectiveness-implementation trial is to test a family strengthening (FS) model delivered through multiple family groups (MFG) combined with a virtual peer mentoring program called TeenAge Health…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Antisocial Personality Disorder, Anxiety
- Trial name
- RRF4H (NCT06176638)
- Testing
- RRF4H Combination Intervention
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Alcohol Drinking, Trauma, Psychological
Development of a Culturally Grounded, Trauma-Informed Alcohol Intervention With a Reserve-Dwelling First Nation Group
The objective of this project is to develop and obtain preliminary data on a culturally grounded, trauma-informed alcohol intervention.
- Conditions
- Alcohol Drinking, Trauma, Psychological, Historical Trauma
- Trial name
- NativeHEALTH (NCT05363878)
- Testing
- Native HEALTH
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Rhode Island
Adolescent Pregnancy
Family Intervention to Improve Maternal and Child Mental Health
This pilot study will assess the acceptability, feasibility and efficacy of a family-based intervention to improve maternal and child mental health by increasing maternal sensitivity and decreasing offspring abuse among…
- Trial name
- MCMH (NCT04700059)
- Testing
- Virtual perinatal home visiting
- Where
- Peru
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Psychological Stress, Depression
Psilocybin-Assisted Therapy for Intergenerational Trauma
This is an open-label psilocybin-assisted therapy study that will examine the safety and tolerability of psilocybin-assisted therapy in the offspring of genocide survivors with mood and anxiety disorders.
- Conditions
- Psychological Stress, Depression, Anxiety
- Trial name
- NCT06899165
- Testing
- Psilocybin, Integration sessions
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rachel Yehuda
Psychological Trauma
To Repeat or Not to Repeat - Preventing Intergenerational Transfer of Adverse Childhood Experiences
The main aim of the study is to examine patients' and therapists' experiences with prenatal psychotherapy provided to pregnant women with adverse childhood experiences and how this may influence intergenerational transmission of…
- Trial name
- NCT04528589
- Testing
- prenatal psychotherapy
- Where
- Norway
- Volunteers
- 23 people
- Sponsor
- University Hospital, Akershus