Clinical trials: Integrated Assessment
Cancer-related Fatigue, Neoplasms (Cancer / Tumors)
Integrated Chinese and Western Therapy for Cancer-Related Fatigue
Cancer-related fatigue (CRF) is a common and debilitating symptom in patients with cancer. Evidence-based non-pharmacological approaches include sleep hygiene, physical activity, nutritional management, and traditional Chinese…
- Trial name
- NCT07445243
- Testing
- Integrated Chinese and Western Holistic Care Program
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Taichung Tzu Chi Hospital
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Sexual Dysfunction, Pelvic Floor Disorders
Improving Women's Function After Pelvic Radiation
The purpose of the study is to develop and test an intervention combining physical therapy (PT) and coping skills training to improve women's sexual function after pelvic radiation.
- Conditions
- Sexual Dysfunction, Pelvic Floor Disorders, Gynecologic Cancer
- Trial name
- NCT04544735
- Testing
- Integrated Physical Therapy and Coping Skills Training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Patients With PICC-Line
SHERLOCK 3CG vs. Fluoroscopy in Implantation of PICC-Line
Peripherally inserted central catheters, or PICC lines, has now been successfully in use for many years, especially in the chemotherapeutic treatment of oncologic patients or in parenertal nutrition.
- Trial name
- 3CG (NCT02929368)
- Testing
- PICC implantation under fluoroscopy, PICC Implantation under Sherlock System
- Where
- Germany
- Volunteers
- 210 people
- Sponsor
- Jena University Hospital
Prostate Cancer
PET/MRI to Stage Prostate Cancer Patients
The main goal of this phase II clinical trial is to define a novel approach of staging prostate cancer (PCa) patients by using a fully integrated positron emission tomography/ magnetic resonance imaging (PET/MRI) system with…
- Trial name
- NCT06484361
- Testing
- 68Ga-PSMA, 68Ga-RM2
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Pneumonia, Primary Health Care
Tools for the Integrated Management of Childhood Illness (TIMCI): Evaluation of Pulse Oximetry & Clinical Decision Support Algorithms in Primary Care
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Pneumonia, Primary Health Care, Child Health, Hypoxia
- Trial name
- TIMCI (NCT04910750)
- Testing
- Pulse oximetry, Clinical Decision Support Algorithm
- Where
- 27 sites in Tanzania
- Volunteers
- 167,517 people
- Sponsor
- Swiss Tropical & Public Health Institute
Stroke, Aphasia
rTMS in Aphasic Patients With Neuroimage Assessments
The refinement of repetitive transcranial magnetic stimulation (rTMS) has highlighted its merit in terms of learning programs as a treatment for aftereffect augmentation.
- Trial name
- NCT03059225
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Stroke
Brain-computer Interface With Plantar Pneumoorthoses for Post-stroke Rehabilitation
STUDY PURPOSE The investigators are testing a new rehabilitation system that helps stroke patients recover their ability to walk and think more clearly.
- Trial name
- BRAIN-WALK (NCT07081308)
- Testing
- NIRS-BCI-pneumoorthesis
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Research Center of Neurology, Russia
Moderate-severe Chronic Kidney Disease Not Treated With Dialysis, Diabetic Kidney Disease, HgbA1c Less Than 8.5
Exercise Study Testing Enhanced Energetics of Mitochondria Video Integrated Delivery of Activity Training in CKD
Skeletal muscle dysfunction (sarcopenia) is an under-recognized target organ complication of CKD with substantial adverse clinical consequences of disability, hospitalization, and death.
- Trial name
- ESTEEM-VIDA (NCT02923063)
- Testing
- Combined Aerobic and Resistance Exercise via videoconferencing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Davis
Borderline Coronary Stenoses Assessment, Fractional Flow Reserve, Plaque Composition
INTegrated Assessment of intERmediate Coronary Stenoses by Fractional Flow rEserve (FFR) and Near-infraREd Spectroscopy (NIRS)
Revascularization of borderline coronary stenoses (40-70%) is usually driven by fractional flow reserve (FFR) which expresses the physiological significance of a lesion and tells the operator whether PCI may reduce the rate of…
- Trial name
- INTERFERE (NCT02985112)
- Testing
- FFR and IVUS-NIRS
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- S.M. Misericordia Hospital
Neurosciences
Studying the Neuronal Basis of Human Social Cognition
This proposal aims to study the role that the dorsal prefrontal cortex plays in human social cognition.
- Trial name
- NCT05324579
- Testing
- Behavioral testing during neuronal recordings
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Health Behavior, Sleep
Project A: Integrated Approaches to Improving the Health and Safety of Health Care Workers
While most of the research on integrated approaches of occupational health and safety and worksite health promotion to date has focused on manufacturing settings, employment is shifting to the service sector.
- Conditions
- Health Behavior, Sleep, MSDs, Dietary Habits
- Trial name
- NCT01841983
- Testing
- Be Well Work Well
- Where
- 3 sites in United States
- Volunteers
- 9,500 people
- Sponsor
- Harvard School of Public Health (HSPH)
Rheumatoid Arthritis
Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis
The group used a randomized controlled trial to conduct a post-marketing re-evaluation study of Wangbi granules. The study was conducted to observe the degree of clinical remission in rheumatoid arthritis patients with low…
- Trial name
- NCT05540938
- Testing
- Wangbi granules, Wangbi granules simulant
- Where
- China
- Volunteers
- 340 people
- Sponsor
- China-Japan Friendship Hospital
Hepatocellular Carcinoma (HCC)
A Study to Compare the Efficacy, Safety, Immunogenicity, and Pharmacokinetic Profile of HLX13 with YERVOY As a First-Line Treatment for Patients with Unresectable Hepatocellular Carcinoma
This is a multicenter, randomized, double-blind, parallel-controlled integrated phase I/III clinical study to evaluate the efficacy, safety, PK, and immunogenicity of HLX13 and YERVOY® in patients with unresectable hepatocellular…
- Trial name
- NCT06841185
- Testing
- HLX13, US-sourced YERVOY®, EU-sourced YERVOY®
- Volunteers
- 656 people
- Sponsor
- Shanghai Henlius Biotech
Osteoporosis With Current Fragility Fracture
Partnership for Applied Research in Fracture Prevention Programs for the Elderly
During their lifetime, approximately 50% of Canadian women and 30% of Canadian men will experience at least one fracture due to bone fragility (FF).
- Trial name
- OPTI-FRAC (NCT01745068)
- Testing
- Integrated program
- Where
- 10 sites in Canada
- Volunteers
- 631 people
- Sponsor
- Université de Sherbrooke
Primary and Secondary Brain Tumors
Integrated PET/MR Imaging With Amino Acid Radiotracers in the Evaluation of Brain Neoplasms: Assessing Diagnostic Accuracy and Therapeutic Response
Evaluation of the diagnostic and prognostic role of PET with Amino Acid Radiotracers associated with simultaneous acquisition of MRI with administration of paramagnetic contrast medium based on Gadobutrol in assessing diagnostic…
- Trial name
- PETMR_ATHENA02 (NCT07211360)
- Volunteers
- 270 people
- Sponsor
- IRCCS San Raffaele
Diabete Type 2, Obesity & Overweight
Artichoke By-products Rich in Hydroxycinnamic Acids and Mediterranean Diet for Type 2 Diabetes Prevention.
The ARTI-UP study evaluates whether daily consumption of a supplement made from artichoke by-products, rich in hydroxycinnamic acids (HCAs), in combination with an energy-restricted Mediterranean diet (erMeDiet), can improve…
- Conditions
- Diabete Type 2, Obesity & Overweight, Insulin Resistance Syndrome
- Trial name
- ARTI-UP (NCT07415720)
- Testing
- Artichoke by-product capsules, Energy-restricted Mediterranean diet (erMeDiet), Physical activity
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Early Childhood Development
Evaluation of the iMBC/ECD Model in Ghana
The Duke research team will work with Catholic Relief Services (CRS) and lead the design and implementation of a cluster-randomized trial in Northern Ghana to assess the impact of the Integrated Mothers and Babies Course \& Early…
- Trial name
- NCT03665246
- Testing
- Integrated Mothers and Babies Course
- Where
- Ghana
- Volunteers
- 378 people
- Sponsor
- Duke University
Diabetes Mellitus, Non-Insulin-Dependent
Effectiveness and Cost-effectiveness of the Diabetes Integrated Care Breakthrough Collaborative
The study tests whether implementing professional evidence-based guidelines and best practices for diabetes care -through participation of multidisciplinary teams in a Breakthrough collaborative- results in an improvement of…
- Trial name
- NCT00160017
- Testing
- Breakthrough collaborative
- Where
- 52 sites in Netherlands
- Volunteers
- 1,861 people
- Sponsor
- Radboud University Medical Center