Clinical trials: Insulin Resistance Syndrome
Inflammation, Metabolic Syndrome
Daily Vinegar Ingestion and Metabolic Health
The purpose of this study is to determine if vinegar ingestion promotes beneficial changes to metabolic health parameters in healthy, overweight adults.
- Conditions
- Inflammation, Metabolic Syndrome, Depression
- Trial name
- NCT05698381
- Testing
- Liquid vinegar, Vinegar pill
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Metabolic Syndrome
Effect of a High-Protein Diet and/or High-Intensity Training on Metabolic Syndrome
The objective of this study is to determine the combined effects of a high-protein diet and high-intensity training on metabolic syndrome risk factors in women aged 30-65.
- Trial name
- EPHIT (NCT01622634)
- Testing
- Sprint Interval Exercise, Higher PRO Diet, Higher CARB Diet
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Cardiovascular Risk Factors, Metabolic Syndrome
White Fish for Cardiovascular Risk Factors in Patients With Metabolic Syndrome: the WISH-CARE Study
The investigators performed this study to evaluate the efficacy of regular ingestion of white fish to reduce cardiovascular risk factors in patients with the metabolic syndrome, compared to a diet with no fish or seafood at all.
- Trial name
- NCT01758601
- Testing
- Dietary intervention with 7 servings oh white fish per week (each serve consisted of 100g of frozen Namibia hake, Pescanova S.A., Pontevedra, Spain), Previous alimentary habits, avoiding any significant nutritional imbalance, as well as any fish or seafood
- Where
- Spain
- Volunteers
- 273 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Metabolic Syndrome
Promoting Healthy Habits in Metabolic Syndrome
A randomized controlled trial will be conducted to evaluate the effectiveness of the Habit Design (HD) approach in a corporate health context over the course of one year in subjects with metabolic syndrome.
- Trial name
- NCT04262401
- Testing
- Standard health coaching, Habit-focused health coaching
- Where
- United States
- Volunteers
- 424 people
- Sponsor
- Habit Design
Psychotic Disorders, Bipolar Disorder
Comparison of Aripiprazole Versus Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI
The purpose of this study is to compare abdominal weight gain and fat distribution in people taking aripiprazole versus risperidone or quetiapine, to people not taking any of these antipsychotic medications.
- Conditions
- Psychotic Disorders, Bipolar Disorder, Metabolic Syndrome X
- Trial name
- CALM (NCT01739127)
- Testing
- Aripiprazole, Risperidone/Quetiapine
- Where
- Canada
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Psoriasis, Metabolic Syndrome
Clinical Study of PET/CT and Association With Metabolic Syndrome/Depressive Symptoms in Psoriasis
Psoriasis is associated with increases in markers of inflammation in the skin and blood and increasingly is thought to be a systemic inflammatory disease and risk factor for incident diabetes mellitus, myocardial infarction…
- Conditions
- Psoriasis, Metabolic Syndrome, Depression
- Trial name
- NCT01661127
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Pusan National University Hospital
Overweight , Obesity, Abdominal Obesity-Metabolic Syndrome
Body Weight Reduction and Metabolic/Biochemical Parameters in Overweight or Obesity
This was a single-center prospective observational cohort study conducted in Poland in the context of routine metabolic outpatient care.
- Trial name
- NCT07645105
- Testing
- Routine Lifestyle-Based Weight Reduction Management
- Where
- 2 sites in Poland
- Volunteers
- 53 people
- Sponsor
- Medical University of Silesia
Obesity, Sarcopenia
Pilot Study of the Human Metagenome in Metabolic Diseases
This is a cohort study to understand the role of the human metagenome, and associated metabolites, in health and in various diseased states, in particular obesity as well as sarcopenia.
- Conditions
- Obesity, Sarcopenia, Sarcopenic Obesity, Chronic Inflammation
- Trial name
- NCT06363253
- Testing
- No specific intervention
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Metabolic Syndrome, Protection Against
Personalised Advice for the Prevention of Metabolic Syndrome
Rationale: Improving dietary behaviours in view of optimising risk factors of metabolic syndrome requires behaviour change strategies. Tailored dietary advice, i.e.
- Trial name
- NCT04595669
- Testing
- Personalised advise
- Where
- Netherlands
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Colorectal Neoplasms, Microbiota
Predictive Value of Innovative Prognostic Markers (Gut Microbiota, Sarcopenia, Metabolic Syndrome and Obesity) on Surgical and Oncologic Results in the Management of Sporadic Colorectal Adenocarcinoma.
Colorectal cancer (CRC), second leading cause of cancer worldwide, is associated with a poor prognosis, especially in patients with advanced disease.
- Conditions
- Colorectal Neoplasms, Microbiota, Prognosis, Metabolic Syndrome
- Trial name
- METABIOTE (NCT03843905)
- Testing
- no intervention
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Clermont-Ferrand
Gestational Diabetes Mellitus
Gestational Diabetes Mellitus and Cardiometabolic Syndrome in Offspring
Gestational Diabetes Mellitus (GDM) has long been known as leading to macrosomias, neonatal hypoglycemias and other complications which are treatable and preventable.
- Trial name
- DG3 (NCT01490372)
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Université de Sherbrooke
Metabolic Syndrome X
Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in Obesity
The combination of high blood pressure and having central obesity is an increasing important factor for heart disease in men and women.
- Trial name
- NCT00608465
- Testing
- Eplerenone, Ramipril
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Polycystic Ovarian Syndrome (PCOS), Aerobic Exercise
Effects of Aerobic Exercise Training Program in Females With Insulin Resistant Polycystic Ovarian Syndrome
Design: RCT Randomized Clinical Trial Non Probability Convenient Sampling Technique Duration of treatment: 25 weeks 2 groups; (group A=30) SSAET +Normal routine medication+ Normal Dietary Plan , Other group (Group B=30) with…
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Aerobic Exercise, Walking
- Trial name
- SSAET (NCT07157371)
- Testing
- Supervised structured aerobic exercise training, Walk
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Metabolic Syndrome, Cardiovascular Diseases
Effects of Coenzyme Q10 Supplement on Cardiovascular Risk Factors in Subjects at High Risk of Metabolic Syndrome
This study aims to evaluate the ameliorating effect of coenzyme Q10 supplementation on cardiovascular risk factors in high risk population for metabolic syndrome, including blood lipid metabolism, insulin resistance, blood…
- Trial name
- NCT06506630
- Testing
- coenzyme Q10
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Tian Zezhong
Metabolic Syndrome
Comparative Effect of Nebivolol vs. Metoprolol on Insulin Sensitivity and Fibrinolytic Balance in Metabolic Syndrome
Test the hypothesis that nebivolol treatment improves fibrinolytic balance and insulin sensitivity compared to metoprolol treatment in individuals with metabolic syndrome.
- Trial name
- NCT00775671
- Testing
- Nebivolol, Metoprolol
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Depression Anxiety Disorder
Effect of Probiotics "Psychobiotics" on Depression and Metabolic Syndrome in Saudi Arabia
The goal of this clinical trial is to assess the effect of commercial multi-strains psychobiotics supplementation as an ad-on therapy on depressive symptoms and metabolic syndrome components (HDL-C, FPG, TGs, WC, BP) in adult…
- Trial name
- NCT06765057
- Testing
- Winclove's Ecologic® Barrier Probiotics
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Roaa Ahmed Alkreadees
Metabolic Syndrome
Effects of Arom Digest Slim on Metabolic Profile and Food Behaviour in Overweight Persons
The present study aims to evaluate the efficacy of Arom Digest Slim in facilitating weight reduction along with a series of minimal nutritional interventions.
- Trial name
- NCT03533881
- Testing
- Arom Digest Slim, Nutritional changes
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SC Aromaarmony SRL
Psoriasis, Metabolic Syndrome
Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome
This study was a randomized, open-label, parallel-group, active comparator controlled study with two treatment arms designed to answer the question whether the combination of Secukinumab with lifestyle intervention could…
- Trial name
- METABOLYX (NCT03440736)
- Testing
- Secukinumab, Life-style intervention
- Where
- 75 sites in Germany
- Volunteers
- 781 people
- Sponsor
- Novartis Pharmaceuticals
PCOS (Polycystic Ovary Syndrome), Insulin Resistance
Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder frequently associated with obesity, insulin resistance (IR), and metabolic dysfunction.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI>30)
- Trial name
- NCT07770711
- Testing
- Metformin, İnositol, Folic Acid
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dicle University
Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
This phase II trial studies how well an exercise program and continuous Fitbit monitoring work for managing metabolic syndrome and cardiovascular disease risk in patients with prostate cancer that has spread to other places in…
- Conditions
- Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
- Trial name
- NCT05054296
- Testing
- Educational Intervention, Exercise Intervention, FitBit
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
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