Clinical trials: Insulin Resistance Syndrome
Adolescent Obesity, Hypertension,Essential
Treatment and Handling Severe Obesity-Related Comorbidities in Adolescents Through Exercise
The main objective of this project is to analyze the effect of a tailor-made, one-to-one, exercise program (aiming to treat and handle obesity-related comorbidities in adolescents with severe obesity at high risk of…
- Conditions
- Adolescent Obesity, Hypertension,Essential, Non-Alcoholic Fatty Liver Disease, Dyslipidemias
- Trial name
- THOR-X (NCT06520800)
- Testing
- Treatment and handling obesity-related comorbidities in adolescents through exercise
- Volunteers
- 24 people
- Sponsor
- University of Lisbon
Metabolic Syndrome, Obesity
Low-intensity Exercise in Metabolic Syndrome
People with metabolic syndrome (MetS) are characterized by a lower quality of life in terms of reduced vital activity, emotional state, and social functioning.
- Conditions
- Metabolic Syndrome, Obesity, Hypertension, Hyperlipidemias
- Trial name
- NCT04346836
- Testing
- Low-intensity, general-fitness exercises, Psychoeducation
- Where
- Poland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Metabolic Syndrome, Endothelial Dysfunction
Effect of Eplerenone on Endothelial Function in Metabolic Syndrome
Patients with the metabolic syndrome (MetSyn) are at increased risk for cardiovascular mortality and morbidity.This increased cardiovascular risk is attributed to metabolic dysregulations like impaired glucose tolerance or…
- Trial name
- MetSyn (NCT01319344)
- Testing
- Eplerenone
- Where
- 2 sites in Germany
- Volunteers
- 42 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Adolescent Obesity, Life Style, Healthy
CArdioMetabolic Prevention in Adolescents
The aim of the CArdioMetabolic Prevention (CAMP) pilot study is to investigate the effect of a group intervention on lifestyle in adolescents and on at least one adult family member.
- Conditions
- Adolescent Obesity, Life Style, Healthy, Body Weight Changes, Cardiometabolic Syndrome
- Trial name
- CAMP (NCT05350111)
- Testing
- lifestyle education
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Sleep Apnea, Obstructive, Exercise Training Therapy
Effects of an Individualized Training Program on Severity Markers of Obstructives Sleep Apnea/Hypopnea Syndrome (OSAS)
There are two types of treatments depending on the severity of Obstructive Sleep Apnea/Hypopnea Syndrome (OSAS): - for the treatment of severe (AHI> 30/h), the standard treatment is Continuous Positive Airway Pressure (CPAP).
- Trial name
- REEVASAS (NCT01256307)
- Testing
- training and educational program, educational program
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Montpellier
Cardiovascular Diseases, Obesity
Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
SWIFT-CORE-101 is a single site survey study designed to assess potential participants' eligibility to screen for industry-sponsored clinical trials.
- Conditions
- Cardiovascular Diseases, Obesity, PreDiabetes, Diabetes Type 2
- Trial name
- SWIFT-CORE-101 (NCT06412536)
- Testing
- Blood work
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brooklyn Clinical Research
NAFLD
Correlation Between Hepatic Fibrosis and Cardiovascular Risk Evaluated by Non-invasive Tests in Patients With NAFLD
This study aims to examine the link between Non-Alcoholic Fatty Liver Disease (NAFLD) and cardiovascular diseases by studying the association between liver fibrosis degree and cardiovascular risk factors.
- Trial name
- Cardio-NASH (NCT04774302)
- Where
- 2 sites in France
- Volunteers
- 292 people
- Sponsor
- Clinique Pasteur
HIV Infections, Hepatic Steatosis
Pioglitazone to Treat Fatty Liver in People With HIV Infection
This study will determine whether pioglitazone (Actos, a drug approved to treat diabetes, can benefit HIV-infected people with fatty liver.
- Conditions
- HIV Infections, Hepatic Steatosis, Insulin Resistance
- Trial name
- NCT00441272
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diabetes Mellitus, Type 2, Overweight and Obesity
The Metabolic Impact of Intermittent Carbohydrate Restriction in Individuals With Type 2 Diabetes
The primary aim of this randomized cross-over intervention study is to investigate the effect of four weeks of intermittent carbohydrate restriction (alternating between two days of normal dietary intake and two days of…
- Conditions
- Diabetes Mellitus, Type 2, Overweight and Obesity, Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
- Trial name
- INTERCARB (NCT06144593)
- Testing
- Dietary macronutrient composition
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Hvidovre University Hospital
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Anorexia Nervosa, Thrombosis
Thromboembolism in Anorexia Nervosa
BACKGROUND: Sudden death due to thromboembolic (TE) events in patients with anorexia nervosa (AN) is well known. However, the incidence of TE events and the hemostatic balance in patients with AN are sparsely investigated.
- Conditions
- Anorexia Nervosa, Thrombosis, Thromboembolism
- Trial name
- TEAN (NCT05575466)
- Testing
- Blood samples, Questionnaires
- Where
- 5 sites in Denmark, Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Lupus Nephritis
the Association Between Metabolic Syndrome and Its Components With Lupus Nephritis in Systemic Lupus Erythematosus Patients
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that involve s many different organs and display a variable clinical course.
- Trial name
- NCT05964751
- Testing
- lipid profile, fasting blood suger
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sohag University
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis
MASLD in Type 2 Diabetes in Primary Care - a Follow-up Study
The goal of this observational study is to understand how metabolic dysfunction-associated steatotic liver disease (MASLD) changes over time in individuals with type 2 diabetes who previously participated in the EPSONIP study.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis, Advanced Fibrosis, Sarcopenia
- Trial name
- EPSOMIP2 (NCT07312136)
- Where
- Sweden
- Volunteers
- 317 people
- Sponsor
- Linkoeping University
Metabolic Syndrome
Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic Syndrome
Phase III randomized controlled trial on men and women with Metabolic syndrome (MetS) to test the hypothesis that comprehensive life-style changes and/or metformin treatment prevent age-related chronic non-communicable diseases…
- Trial name
- MeMeMe (NCT02960711)
- Testing
- Metformin Hydrochloride 850 MG Oral Tablet [Glucophage], Ludipress, mg stereate, micronized hydrated silica, talcum
- Where
- Italy
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Metabolic Syndrome
Pilot Study to Evaluate the Effect of Two Microalgae Consumption on Metabolic Syndrome
The purpose of this study is to evaluate the effect of the consumption of two microalgae Chlorella vulgaris and Arthrospira platensis (Spirulina) on some biomarkers of metabolic syndrome: Total cholesterol, HDL cholesterol, LDL…
- Trial name
- ALGAENERGY (NCT05343858)
- Testing
- Experimental: Group 1: Spirulina platensis, Experimental: Group 2: Chlorella vulgaris
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Shift-Work Related Sleep Disturbance, Metabolic Syndrome
Health Effect of Canola Oil Consumption in Shift Workers
Shift work is associated with a higher risk of the development of cardiometabolic syndrome (CMtS) than in people working only during the day.
- Conditions
- Shift-Work Related Sleep Disturbance, Metabolic Syndrome, Diet Modification, Work-Related Condition
- Trial name
- NCT03977558
- Testing
- Intervention group, Control group
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Metabolic Syndrome
Exercise Training on Metabolic Syndrome Severity in Employees
Hypothesis: An occupational 6 months physical exercise training will lead to better health behaviour and improve the severity of the metabolic syndrome.
- Trial name
- NCT03293264
- Testing
- Exercise training group
- Where
- Germany
- Volunteers
- 314 people
- Sponsor
- Hannover Medical School
Aging, Menopause
Gonadal Hormone, Gonadotropin and Cardiovascular Events
Deficiency in gonadal hormone has been considered to play a role in ageing related increased incidence of cardiovascular events. But the mechanism has not been fully elucidated.
- Trial name
- NCT02810821
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Metabolic Syndrome X
Effects the Glycemic Index on Metabolic Risk Markers
Recent population studies have shown that the glycemic index (GI) of food products is positively associated with the risk of developing type 2 diabetes and cardiovascular disease (CVD).
- Trial name
- NCT00695825
- Testing
- Low GI+high GI, High GI+low GI
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Dyslipidemias
Efficacy and Safety of Pitavastatin/Ezetimibe in Dyslipidemia Patients With Metabolic Syndrome: An Observational Study
The purpose of this study is to evaluate the efficacy and safety of Pitavastatin/Ezetimibe tablets (a fixed-dose combination of Pitavastatin and Ezetimibe) in patients with dyslipidemia who also have metabolic syndrome in a…
- Trial name
- PIVOT (NCT07523971)
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- JW Pharmaceutical
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