Clinical trials: Insulin Resistance Syndrome
Obstructive Sleep Apnea, Metabolic Syndrome X
Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress
The purpose of this study is to define the mechanism(s) through which Obstructive Sleep Apnea/Hypopnea (OSAH) promotes abnormal metabolic processes which characterize the metabolic syndrome.
- Trial name
- NCT00177892
- Testing
- sleep disruption, sleep with and without positive pressure
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
HIV Infections
Endothelial Dysfunction as a Risk Factor in HIV Study
Highly active antiretroviral therapy (HAART) has proven effective in altering the natural history of HIV infection in many patients. However, this therapy may not be sustainable because of the toxicities of the medications.
- Trial name
- NCT00039663
- Testing
- Pravastatin, Gemfibrozil, Rosiglitazone
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Hyperandrogenism, Metabolic Cardiovascular Syndrome
Phlebotomy and Polycystic Ovary Syndrome
AIMS To study the effects of the decrease in iron tissue depots after scheduled bloodletting on insulin sensitivity, carbohydrate metabolism, classic and non-classic cardiovascular risk factors in patients with functional…
- Trial name
- NCT02460445
- Testing
- Phlebotomy, ethinylestradiol, Cyproterone Acetate
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Manuel Luque Ramírez
Bladder, Lower Urinary Track Symptoms
Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic Syndrome
Overactive bladder (OAB) is a common condition that causes urinary urgency, frequent urination, and nocturia, which can significantly affect quality of life.
- Conditions
- Bladder, Lower Urinary Track Symptoms, Metabolic Syndrome, Urgency-Frequency
- Trial name
- NCT07563764
- Testing
- Low-Energy Extracorporeal Shock Wave Therapy (LiESWT)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- KMUHIRB-F(I)-20230051
Overweight (BMI > 25), Obesity &Amp; Overweight
Effects of Three Dietary Strategies on Body Composition and Metabolic Health in Adults With Overweight or Obesity
This study aims to compare the effects of three dietary interventions-a traditional Mediterranean diet, a Mediterranean low-carbohydrate diet, and a high-protein diet-on body composition, metabolic health markers, and metabolic…
- Conditions
- Overweight (BMI > 25), Obesity &Amp; Overweight, Metabolic Syndrome (MetS), Cardiometabolic Risk Factors
- Trial name
- NCT07314177
- Testing
- Mediterranean Diet, Mediterranean Low-Carbohydrate Diet, High-Protein Diet
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Prediabetes
The Prevalence of Metabolic Syndrome and Its Associated Factors in an Urban City
The secondary objective is to evaluate the agreement between these criteria and the prevalence of concordant and discordant according to different criteria.
- Trial name
- NCT00308672
- Where
- Taiwan
- Volunteers
- 3,000 people
- Sponsor
- China Medical University Hospital
Metabolic Syndrome, Obesity
Body Weight and Vascular Function
An increased body mass impairs vascular function (VF), an important characteristic of subjects suffering from type 2 diabetes and a risk marker for cardiovascular diseases.
- Trial name
- NCT01675401
- Testing
- Weight-loss treatment, No-weight loss treatment
- Where
- Netherlands
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Stroke, Ischemic
The Association Between Obesity-Related Indicators and Adverse Outcomes in Ischemic Stroke Patients
This study encompasses two cohorts: a retrospective cohort derived from a genuine clinical environment and a national multicenter prospective cohort for secondary analysis.
- Trial name
- NCT06165107
- Testing
- No intervention
- Where
- China
- Volunteers
- 18,374 people
- Sponsor
- Qin Zhang
Dyslipidemia, Diabetes
Meta-analyses of Dietary Pulses and Cardiometabolic Risk
Dietary pulses, more commonly known as "legumes", are generally recognized as healthy components of the diet. Canada's Food Guide encourages consumptions of meat alternatives, such as beans "more often"; and the dietary…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01594567
- Testing
- Dietary pulses
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Healthy Volunteers, Overweight
Evaluation of Body Iron Stores in Overweight Healthy Volunteers
Normal body iron store value in overweight subjects is currently not described in literature. The comparison of this value with body iron levels in patients suffering from dysmetabolic iron overload syndrome (DIOS) could allow to…
- Trial name
- FERNORM (NCT02304874)
- Testing
- Phlebotomy
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Metabolic Syndrome, Insulin Resistance
FTO rs9939609 and PPARy rs1801282 Polymorphisms in Mexican Adolescents
Background and Aims: The presence of the FTO rs9939609 and PPARy rs1801282 polymorphisms suggests changes in energy metabolism; this variation may be responsible for the development of various diseases including obesity.
- Trial name
- NCT02886013
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Asociación Científica Latina A.C.
Diabetes Mellitus, Type 2, Inflammation
Randomized Crossover Study of Magnesium Supplementation
The investigators recent epidemiologic work in several national surveys and cohorts of men and women have shown that dietary patterns high in plant-based foods and phytochemicals are associated with lower plasma levels of…
- Trial name
- NCT00737815
- Testing
- Magnesium Citrate: a total of 500 mg elemental magnesium
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Erectile Dysfunction
Therapeutic Effectiveness of Vardenafil in Patients With Erectile Dysfunction and Metabolic Syndrome in Daily Clinical Practice
The primary goal of this international non-interventional study is to investigate the therapeutic effectiveness of vardenafil (film-coated tablet) in Erectile Dysfunction patients with the Metabolic Syndrome in daily clinical…
- Trial name
- REVITALISE (NCT01106118)
- Testing
- Vardenafil (Levitra, BAY38-9456)
- Where
- 10 sites in Egypt, Israel and 8 more
- Volunteers
- 2,289 people
- Sponsor
- Bayer
Type 2 Diabetes Mellitus, Cardiovascular Abnormalities
Curcumin for Type 2 Diabetic Patients
There are evidence that there is an association between insulin resistance and prolonged hyperinsulinemia or hyperglycemia in Type 2 diabetic patients.
- Trial name
- NCT01052597
- Testing
- curcumin
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Srinakharinwirot University
Overweight, Obesity
Longevity Diet and the Fasting-mimicking Diet
This retrospective clinical study examines the impact of the longevity diet and fasting-mimicking diet (FMD), either alone or combined, on body composition and health indicators.
- Conditions
- Overweight, Obesity, Metabolic Syndrome, Autoimmune Diseases
- Trial name
- NCT07065955
- Testing
- Longevity diet alone or in combination with fasting mimicking diet
- Where
- Italy
- Volunteers
- 365 people
- Sponsor
- Fondazione Valter Longo
Metabolic Syndrome, Diabetes Mellitus
Biomarkers Derived From Adipose Tissue Useful for Diagnosis and Prognosis of Cardiovascular Risk (CVR) in Obese Patient
This study evaluates the relationship between the adipose tissue, as an active component, which can define metabolic phenotypes linked to cardiovascular risk modification post bariatric surgery.
- Conditions
- Metabolic Syndrome, Diabetes Mellitus, Inflammatory Response
- Trial name
- CROP (NCT03561987)
- Testing
- Bariatric surgery
- Volunteers
- 70 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Metabolic Syndrome, Insulin Sensitivity
Seaweed Extract Supplementation and Metabolic Biomarkers
Double blinded, randomized, placebo controlled preliminary pilot exploratory investigation into the effects of brown seaweed extract supplementation, on fasting blood Insulin, fasting blood glucose, insulin sensitivity, blood…
- Trial name
- NCT03853343
- Testing
- Seaweed extract
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BioAtlantis Ltd.
Angina Pectoris, Metabolic Syndrome X
Rosiglitazone Versus Placebo in Chronic Stable Angina
We wish to see if the drug rosiglitazone, currently used in the treatment of type 2 diabetes, could be used as a new treatment for angina when compared with placebo in overweight subjects who do not have overt diabetes.
- Trial name
- NCT00225355
- Testing
- Rosiglitazone
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Glasgow
Metabolic Syndrome
Effect of Fasting With Two Meals on Insulin Resistance Indices of Metabolic Syndrome
this study was conducted to assess the insulin resistance indices in the subjects undergoing Ramadan fasting (diet which consisted of two meals at 12 hours intervals)for a thirty days period.
- Trial name
- NCT00429390
- Testing
- Ramadan Fasting
- Volunteers
- 55 people
- Sponsor
- Free Islamic University of Medical Sciences
NAFLD - Nonalcoholic Fatty Liver Disease, Diabetes
PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies
The main aim of the study is to set up an observational cohort with NAFLD (Non-alcoholic fatty liver disease) at different stage of disease (from simple steatosis to cirrhosis and/or HCC-Hepatocellular carcinoma) and for…
- Conditions
- NAFLD - Nonalcoholic Fatty Liver Disease, Diabetes, Obesity, Metabolic Syndrome
- Trial name
- PROMETEO (NCT04371042)
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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