Clinical trials: Insulin Resistance
Overweight, Glucose Metabolism Disorders
The Physical Activity and Nutrition in Children (PANIC) Study
The Physical Activity and Nutrition in Children (PANIC) Study is a single-centre controlled trial on the effects of a combined physical activity and dietary intervention on cardiometabolic risk factors and other health outcomes…
- Conditions
- Overweight, Glucose Metabolism Disorders, Lipid Metabolism Disorders, Blood Pressure
- Trial name
- PANIC (NCT01803776)
- Testing
- lifestyle counseling
- Where
- Finland
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Mild Cognitive Impairment, Insulin Resistance
Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease
The purpose of the BEAM study is to compare the effects of a low-carbohydrate diet and a lowfat diet for adults with mild memory loss and adults with pre-diabetes.
- Trial name
- BEAM (NCT02984540)
- Testing
- Low-Carbohydrate Diet, Low-Fat Diet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Polycystic Ovary Syndrome, Metabolic Syndrome
Metabolic Syndrome in PCOS: Precursors and Interventions
The purpose of this study is to investigate the metabolic effects of anti-androgens and oral contraceptive pills (OCPs), compared with placebo, in the treatment of women with PCOS.
- Trial name
- NCT00442689
- Testing
- flutamide, ethinyl estradiol 35 mcg and drospirenone 3 mg
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Obesity
Exercise Dose Response for Improving Insulin Sensitivity
Many of the beneficial metabolic effects of endurance exercise training are not due to adaptations to weeks, months, or even years of training, but rather much is due to the response to the most recent exercise session(s).
- Trial name
- NCT01452035
- Testing
- Exercise
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Metabolic Syndrome
Effect of Fucoxanthin on the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
The Metabolic Syndrome (MS) is a cluster of cardiometabolic risk factors, which include abdominal obesity, hyperglycemia, dyslipidemia, and high blood pressure.
- Trial name
- NCT03613740
- Testing
- Fucoxanthin
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- University of Guadalajara
Intermittent Claudication, Metabolic Syndrome X
Prevalence of Metabolic Syndrome in Patients With Intermittent Claudication
Metabolic syndrome, a group of cardiovascular risk factors related to insulin resistance, is a major determinant of cardiovascular mortality. Intermittent claudication is a symptom of an early stage of atherosclerosis.
- Trial name
- NCT00946868
- Where
- Brazil
- Volunteers
- 170 people
- Sponsor
- University of Sao Paulo
Precursors to PCOS
Research Study for Children With a Mother or Sister With Polycystic Ovary Syndrome
In this study, we want to find out more about polycystic ovary syndrome(PCOS). This is a common problem in about 7% of teenage girls. Problems may include irregular periods, extra hair on the face, chest and back areas.
- Trial name
- PCOS (NCT00559390)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Aging, Insulin Sensitivity
Antecedent Metabolic Health and Metformin Aging Study
Aging is the number one risk factor for the majority of chronic diseases. There are no pharmaceutical treatments to slow aging and prolong healthspan.
- Conditions
- Aging, Insulin Sensitivity, Chronic Disease, Mitochondria
- Trial name
- ANTHEM (NCT04264897)
- Testing
- Metformin
- Where
- 2 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Oklahoma Medical Research Foundation
Body Weight, Insulin Resistance
The Effects of Calorie Restriction With or Without Metformin on Weight and Insulin Resistance
This is a study to: Determine the difference between strong hypo-energetic "standard diet advice" and modest hypo-energetic "personal diet advice"; and Determine the influence of insulin-insensitivity on obesity and weight…
- Trial name
- NCT00134290
- Testing
- metformin, "standard diet advice", "personal diet advice"
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- University Hospital, Ghent
Dyslipidemia, Metabolic Syndrome (MetS)
Polyunsaturated Fatty Acids-based Bars Effect on Metabolic Syndrome Patients
This study aimed to manage dyslipidemia through Polyunsaturated fatty acids based bar among patients with metabolic syndrome.
- Trial name
- NCT07627555
- Testing
- Jelly Candy, PUFA Bar
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Inflammation, Obesity
Omega-3 Supplementation Decreases Inflammation and Fetal Obesity in Pregnancy
Randomized, double-blind placebo controlled trial of fish oil to decrease inflammation in pregnancy.
- Conditions
- Inflammation, Obesity, Pregnancy, Fetal Growth
- Trial name
- NCT00957476
- Testing
- Omega-3 Fish Oil
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Syndrome
Gdue Plus a Hypocaloric Mediterranean Diet in Adults With MASLD
This randomized, double-blind, placebo-controlled study evaluated whether Gdue®, a nutraceutical containing extracts of the brown algae Ascophyllum nodosum and Fucus vesiculosus together with chromium picolinate, could improve…
- Trial name
- GDUE (NCT07763626)
- Testing
- Brown Algae and Chromium Picolinate Supplement
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- University of Genova
Metabolic Syndrome, ASCVD
Cardiometabolic Syndrome Response to Therapeutic Lifestyle Changes
Intensive lifestyle intervention has shown to be effective in high risk patient populations and has gathered support from leaders-as outlined in the 2015 consensus paper by the Cardiometabolic Health Alliance.
- Conditions
- Metabolic Syndrome, ASCVD, Lifestyle Risk Reduction
- Trial name
- COSMETIC (NCT04093440)
- Testing
- lifestyle modification
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Holy Cross Hospital, Florida
Type 2 Diabetes
Vitamin D Supplementation to Patients With Type 2 Diabetes
The purpose of the study is to evaluate if supplementation with vitamin D in a dose of 40.000 IU per week will result in improved metabolic control in patients with type 2 diabetes.
- Trial name
- NCT00400491
- Testing
- Cholecalciferol (vitamin D)
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Type 2 Diabetes
Effect of Gynostemma Pentaphyllum Tea in Insulin Sensitivity in Type 2 Diabetic Patients
The aim of the present study was to investigate the effects of Gynostemma Pentaphyllum tea on insulin sensitivity in drug-naïve type 2 diabetic patients.
- Trial name
- NCT01254084
- Testing
- Gynostemma Pentaphyllum tea
- Where
- 2 sites in Vietnam
- Volunteers
- 16 people
- Sponsor
- Hanoi Medical University
Energy Supply; Deficiency, Energy Balance
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality
10 healthy, male, participants will complete a a 5-day baseline assessment (days -5 to -1) and two consecutive 5-day periods of controlled exercise to increase oxidative capacity (3 days of aerobic exercise per period, 15 kcal/kg…
- Conditions
- Energy Supply; Deficiency, Energy Balance, Energy Availability
- Trial name
- NCT05203133
- Testing
- Energy Balance, Energy Deficit, Baseline Assessment
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
PCOS
Exogenous Ketone Supplementation in Females with Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 1 in 5 females of reproductive age. Commonly characterized as a disorder of infertility, PCOS is often accompanied by 3 potent cardiovascular disease (CVD) risk factors: insulin…
- Trial name
- NCT06155708
- Testing
- Ketone, Water
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Insulin Resistance
Correlation Between Continuous Glucose Monitoring and Intermittent Glucose Monitoring Values and Pregnancy Outcomes
We wish to find out if in non-diabetic pregnancies, as well as diabetic pregnancies, additional data obtained by Continuous Glucose Monitoring improves perinatal risk prediction.
- Trial name
- NCT00186004
- Testing
- Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Stanford University
Polycystic Ovary Syndrome
Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S
This study will be carried out in an attempt to know which is more effective, Intermittent fasting diet or resistive exercise program on insulin resistance in obese woman with polycystic ovarian syndrome.
- Trial name
- NCT06882291
- Testing
- Intermittent fasting diet, Resistive exercise program, Medical treatment
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Effect of Magnesium Supplementation on Polycystic Ovary Syndrome
This is a double-blind randomized clinical trial which will start at June 2014 and end on June 2015 in Isfahan city. Serum insulin level is considered as a key variable and the sample size calculated 70 persons (35 persons for…
- Trial name
- NCT02178150
- Testing
- Magnesium Oxide
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
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