Clinical trials: Insomnia, Primary
Insomnia, Primary
Evaluating an Online Mindfulness-Based Intervention for Insomnia
Insomnia has significantly negative impact on work, quality of life, psycho-somatic health on individuals and imposes substantial economic burdens on society.
- Trial name
- NCT04806009
- Testing
- 'Mindful Living With Insomnia (MLWI)' Intervention via WeChat mini-program, 'Cognitive Behavioral Therapy for insomnia (CBT-I)'via WeChat mini-program
- Volunteers
- 1,000 people
- Sponsor
- Central South University
Sleep Initiation and Maintenance Disorders
Efficacy and Safety of Zolpidem-MR Administered Over a Long Term Period as Needed for Insomnia (ZOLONG)
The primary objective of the study is to evaluate the hypnotic efficacy of zolpidem-MR 12.5 mg in comparison with placebo, when administered over a long-term period, on an "as needed" basis, in patients with chronic primary…
- Trial name
- NCT00425243
- Testing
- zolpidem-MR (SL800750)
- Where
- United States
- Volunteers
- 1,025 people
- Sponsor
- Sanofi
Insomnia
Transcranial Magnetic Stimulation for Treatment of Insomnia
Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique that has been approved as a treatment of depression in patients that have not responded to a trial of one antidepressant medication.
- Trial name
- TMSI (NCT02196025)
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Florida
Postoperative Pain Management in Total Knee Arthroplasty
EFFECT OF ZOLPIDEM ON SLEEP QUALITY AND OPIOID CONSUMPTION FOLLOWING PRIMARY TOTAL KNEE ARTHROPLASTY: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
This clinical trial evaluated whether zolpidem could improve sleep quality and postoperative recovery in patients undergoing total joint arthroplasty.
- Trial name
- NCT07801742
- Testing
- Zolpidem 10 mg tablets, Avocado-soybean unsaponifiables 300 mg
- Where
- Argentina
- Volunteers
- 54 people
- Sponsor
- Sanatorio Allende
Insomnia
A Six Week, Double-Blind Randomized, Efficacy and Safety, Sleep Lab Trial With Esmirtazapine (Org 50081) (P05707)
The purpose of this trial is to investigate the efficacy, safety and tolerability of esmirtazapine (Org 50081) compared to placebo in patients with chronic primary insomnia.
- Trial name
- NCT00506389
- Testing
- Esmirtazapine
- Volunteers
- 419 people
- Sponsor
- Merck Sharp & Dohme LLC
Primary Insomnia
A Prospective Active-Reference Study of Gaboxadol in Primary Insomnia
To evaluate the efficacy safety and tolerability of gaboxadol in primary insomnia
- Trial name
- NCT00209937
- Testing
- Gaboxadol
- Volunteers
- 675 people
- Sponsor
- H. Lundbeck A/S
Arthritis, Asthma
Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems
Behavioral problems are part of many of the chronic diseases that cause the majority of illness, disability and death. Tobacco, diet, physical inactivity, alcohol, drug abuse, failure to take treatment, sleep problems, anxiety…
- Conditions
- Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes
- Trial name
- IBHPC (NCT02868983)
- Testing
- Integration
- Where
- United States
- Volunteers
- 4,025 people
- Sponsor
- University of Vermont
Primary Insomnia
Mindfulness and RelaxationTraining for Insomnia (MRTI) on Postmenopausal Women: a Randomized Clinical Trial.
Summary Introduction: Insomnia is a symptom of sleep disorders most prevalent. Primary insomnia, the investigators analyzed, often related to stress states acquired, generalized anxiety and stress, which are important factors…
- Trial name
- NCT01593436
- Testing
- mindfulness training
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Insomnia, Primary
Study of Low Field Magnetic Stimulation (LFMS) on Measures of Sleep
Participants will be recruited and screened through ongoing studies in the sleep and anxiety disorders clinic. Participants with insomnia will be consented to complete several questionnaires, undergo a brief physical exam…
- Trial name
- NCT03050372
- Testing
- LFMS - Active
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Insomnia Chronic, Insomnia
Effects of Insomnia Treatment on Metabolism in Patients With Depression
This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.
- Conditions
- Insomnia Chronic, Insomnia, Insomnia, Primary, Depression
- Trial name
- NCT04719143
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Anxiety Disorders, Major Depression
CBT Versus a Return to Work Intervention for Patients With Common Mental Illness in Primary Care
Background: Common mental illness, such as anxiety disorders and depression, is the main cause for sick leave in Sweden. Cognitive behavior therapy (CBT) has been shown to be effective in alleviating target symptoms of these…
- Conditions
- Anxiety Disorders, Major Depression, Stress Disorders, Primary Insomnia
- Trial name
- CBT vs RTW I (NCT01636791)
- Testing
- Cognitive behavior therapy, Return to work
- Where
- Sweden
- Volunteers
- 211 people
- Sponsor
- Karolinska Institutet
Insomnia, Primary
Effects of Zero-Time Exercise (ZTEx) on Inactive Adults With Insomnia
Objectives: To evaluate the clinical effects of Zero-Time Exercise (ZTEx) for treating insomnia disorder delivered by a training course.
- Trial name
- NCT03155750
- Testing
- Zero Time Exercise, Sleep hygiene education
- Where
- Hong Kong
- Volunteers
- 37 people
- Sponsor
- The Hong Kong Polytechnic University
Anxiety Disorders, Major Depression
CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care
Background: Common mental illness, such as anxiety disorders and depression, is the main cause for sick leave in Sweden. Cognitive behavior therapy (CBT) has been shown to be effective in alleviating target symptoms of these…
- Conditions
- Anxiety Disorders, Major Depression, Stress Disorders, Primary Insomnia
- Trial name
- NCT01667809
- Testing
- Cognitive behavior therapy, Return to work
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Karolinska Institutet
Primary Insomnia
Metabolomics of Insomnia-Related Hyperarousal
Individuals with insomnia have been shown to have higher overall metabolic rates compared to good sleepers, but it is not known which metabolic processes are involved.
- Trial name
- NCT01957111
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Insomnia, Primary
Effects of Zero-Time Exercise (ZTEx) on Inactive Adults With Insomnia Disorder
This randomized controlled trial (RCT) with a longitudinal mixed-method process evaluation aims to (1) determine the effectiveness of a ZTEx intervention program, which is a lifestyle-integrated physical activity program, on…
- Trial name
- NCT04227587
- Testing
- Zero Time Exercise, Sleep hygiene education
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- The Hong Kong Polytechnic University
Primary Brain Tumor, Glioblastoma
CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial
This study seeks to investigate an evidence-based, manualized, behavioral health intervention, Cognitive Behavioral Therapy for Insomnia (CBT-I), in individuals with primary brain tumors (PBT) and insomnia.
- Conditions
- Primary Brain Tumor, Glioblastoma, Astrocytoma, Oligodendroglioma
- Trial name
- CBT-I in PBT (NCT06439420)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Virginia Commonwealth University
Primary Insomnia
Digital Cognitive Behavioral Therapy for Insomnia in China
Digital cognitive behavioral therapy for insomnia (dCBT-i) is found to be effective but is rarely used in China. Hence, the investigators developed an automated Chinese dCBT-i program and examined its feasibility, acceptability…
- Trial name
- NCT05416346
- Testing
- Digital Cognitive Behavioral Therapy, Sleep Hygiene Education (SHE)
- Where
- China
- Volunteers
- 217 people
- Sponsor
- Peking University
Primary Insomnia, Secondary Insomnia
An Efficacy Study of Compound LY2624803 in the Treatment of Patients With Chronic Insomnia
The purpose of this study is to compare an investigational drug (LY2624803) with placebo and with zolpidem in the treatment of outpatients with chronic insomnia.
- Trial name
- SLUMBER (NCT00784875)
- Testing
- LY2624803, zolpidem
- Where
- 49 sites in United States
- Volunteers
- 643 people
- Sponsor
- Eli Lilly and Company
Primary Insomnia
Exploratory Study of Effective Core Formula of Chinese Medicine to Treat Primary Insomnia
The objective of this study is to screen the effective core formulation in insomnia treatment with Chinese medicine with a double-blind, randomized, placebo-controlled trial.
- Trial name
- NCT01613183
- Testing
- Chinese herbal Medicine, the dummy of a Chinese Medicine prescription
- Where
- China
- Volunteers
- 2 people
- Sponsor
- China Academy of Chinese Medical Sciences
Pulmonary Artery Hypertension
Impact of Aerobic Training on Sleep Quality and Aerobic Fitness in Male Patients With Pulmonary Artery Hypertension
This study investigated the effect of 12 weeks of aerobic training on sleep quality and aerobic fitness in patients with Pulmonary arterial hypertension(PAH).
- Trial name
- NCT04337671
- Testing
- Moderate intensity aerobic training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University