Clinical trials: Injection Pain Prevention
Injection Pain, Local Anesthesia Infiltration
Sweet-Tasting Solution Versus Placebo to Reduce Pain During Local Anesthetic Injection in Children
The goal of this clinical trial is to learn whether applying a sugar-free flavored sweet solution (SFSS) before local anesthesia helps reduce injection pain in children.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pain, Injection Pain Prevention
- Trial name
- NCT07279285
- Testing
- Sugar-free-flavored sweet tasting solution
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Injection Site
Efficacy of TEAS On Prevention of Propofol Injection Pain in Children
The purpose of this study is to determine the efficacy of transcutaneous electrical acupoint stimulation for the prevention of propofol injection pain in children.
- Trial name
- NCT05296187
- Testing
- TEAS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Pain
Injectable Diclofenac for the Prevention of Post-operative Dental Pain
This is a prospective, randomised, double-blind, placebo-controlled, parallel group study in approximately 75 patients undergoing surgical removal of an impacted lower third molar.
- Trial name
- DP4 (NCT01706588)
- Testing
- Diclofenac sodium
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- IBSA Institut Biochimique SA
Pain Management, Injection Pain Prevention
Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic
The goal of this clinical trial is to learn whether virtual reality (VR) can be added to routine knee injection appointments at a VA outpatient pain clinic without slowing down or disrupting clinic operations.
- Conditions
- Pain Management, Injection Pain Prevention, Virtual Reality, Feasibility Studies
- Trial name
- NCT07884851
- Testing
- Immersive Virtual Reality
- Volunteers
- 45 people
- Sponsor
- Atlanta VA Medical Center
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lidocaine, Injection Pain
Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated With Medium-/Long-chain Triglycerides
Propofol is widely used in general anesthesia induction, but the occurrence of peripheral intravenous pain is relatively high, causing anxiety, fear and other adverse emotions in patients , aggravating the stress response, and…
- Trial name
- NCT04008433
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Injection Pain
Effect of TEAS on Rocuronium Injection Pain
Pain from the injection of rocuronium is a common side effect during anesthetic practice, occurring in 50%-80% of patients. Several methods have been used to reduce this pain.
- Trial name
- NCT04943367
- Testing
- TEAS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Injection Techniques, Nursing Interventions
Traction, Pressure, and Rapid Muscle Release (TPR) Technique During Intramuscular Injection: Effects on Pain and Patient Satisfaction
This study will be conducted to evaluate the effect of the Traction, Pressure, and Rapid Muscle Release (TPR) technique, an innovative method used during intramuscular vitamin B12 (cyanocobalamin) injections, on patients' pain…
- Conditions
- Injection Techniques, Nursing Interventions, Injection Pain Prevention, Patient Satisfaction
- Trial name
- TPRTDIMI (NCT07499687)
- Testing
- TPR Injection Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Pain, Ecchymosis
Effect of Hypericum Perforatum Oil on Ecchymosis and Pain
Low molecular weight heparin is a drug with anticoagulant and antithrombotic effects. This drug is frequently administered subcutaneously to patients by nurses.
- Trial name
- NCT06367036
- Testing
- Topical hypericum perforatum oil intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Uskudar University
Laparoscopic Cholecystectomy
Nerve Blocks vs Local Injections for Post-op Pain Prevention in Laparoscopic Cholecystectomy in Children
The objective of this study is to compare transversus abdominis plane (TAP) blocks to local wound infiltration (LWI) in terms of postoperative pain control in pediatric patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT03022279
- Testing
- TAP Blocks, local wound infiltration
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Brian Wallace Gray
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Propofol Injection Pain
Arm Elevation for Prevention of Propofol Injection Pain
The purpose of this research is to determine whether a simple technique, temporarily raising the arm during the injection of propofol (a commonly used medication for anesthesia), can reduce the pain that some people experience…
- Trial name
- NCT07785674
- Testing
- Passive arm elevation, Normal saline, Lidocaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Intravenous Injections, Vaccination
Efficacy of the Buzzy® Device on the Prevention of Health Care Induced Pediatric Pain in a Vaccination Center
In vaccination centers, venipunctures and vaccinations are sources of pain and anxiety in pediatric patients. Prior painful experiences can reduce the acceptance of later health care, hence making it more difficult for both…
- Trial name
- DOLVAX (NCT03220555)
- Testing
- Buzzy® device, EMLAPATCH (lidocaine, prilocaine)
- Where
- 3 sites in France
- Volunteers
- 220 people
- Sponsor
- Nantes University Hospital
Injection Site Irritation
The Prevention of Pain Associated With Rocuronium Injection
The purpose of this study is to determine whether efficacy of different doses of lidocain and acetaminophen for the prevention of rocuronium injection pain and frequency of withdrawal movements during the general anesthesia…
- Trial name
- NCT02524743
- Testing
- acetaminophen, Lidocaine
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Pain, Radiating
Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain
Cervical radicular pain is a common cause of disability and pain in the upper extremity and neck with an annual incidence of 83.2/100,000 (1).
- Trial name
- SPIES (NCT02226159)
- Testing
- Lidocaine, Lidocaine with Dexamethasone
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Injection Pain Prevention, Injection Pain
The Effect of Simultaneous Versus Sequential Intramuscular Vaccine Injections on Pain Levels in Infants
This study was designed as a randomized controlled trial comparing simultaneous and sequential administration of intramuscular vaccines in infants.
- Trial name
- NCT07455305
- Testing
- Simultaneous injection, Sequential injection
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Shotblocker, Injection Pain Prevention
The Effect of SHOTBLOCKER
This study was conducted as a randomized controlled experimental cross over study to examine the effect of injection pain, anxiety and comfort level with the use of Shotblocker in geriatric patients undergoing subcutaneous…
- Conditions
- Shotblocker, Injection Pain Prevention, Pain, Anxiety
- Trial name
- SHOTBLOCKER (NCT06956066)
- Testing
- shotblocker
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul Medeniyet University
Pain
Prevention of Propofol Injection Pain
Pain on injection of propofol is a comman problem. The investigators planned to evaluate the effect of propofol-fentanyl mixture on propofol injection pain and compare it with fentanyl pretreatment and control groups.
- Trial name
- VRS (NCT02203175)
- Testing
- saline, fentanyl, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Yeditepe University Hospital
Propofol Injection Pain
Comparison of Bier Block and Lidocaine-Propofol Mixture for Prevention of Propofol Injection Pain
The goal of this clinical trial was to evaluate methods to prevent pain on intravenous administration of propofol during induction of anesthesia.
- Trial name
- BBLP (NCT07285980)
- Testing
- propofol, Lidocaine - Propofol Mixture, Lidocaine - Bier Block
- Where
- Tunisia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Asma Ladib
Procedural Pain
Intravenous Nalbuphine Versus Lidocaine for Prevention of Propofol Injection Pain
Propofol is a commonly used intravenous anesthetic agent, but its administration is frequently associated with injection pain, causing patient discomfort and agitation.
- Trial name
- NCT07422558
- Testing
- Nalbuphine, Lidocaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex