Clinical trials: Inhalation; Gas
Acute Mountain Sickness, High Altitude
CO2 Supplement for Treatment of Acute Mountain Sickness
It was reported that up to 76% people who rapidly ascend to the altitude higher than 4500 m without sufficient acclimatization will have AMS which often develops 6-8 hours after reaching at high altitude.
- Conditions
- Acute Mountain Sickness, High Altitude, Inhalation; Gas
- Trial name
- NCT06393998
- Testing
- Breathing with CO2 during daytime and night at high altitude, Sleep and doing exercise test under inhalation of air
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Uterine Myoma, Ovarian Cyst
The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position
In patients undergoing gynecologic laparoscopic surgery with trendelenburg position, the disturbance of pulmonary gas exchange frequently occurs due to high intra-abdominal pressure.
- Conditions
- Uterine Myoma, Ovarian Cyst, Laparoscopic Gynecologic Surgery
- Trial name
- NCT01379313
- Testing
- conventional I:E ratio, 1:1 ratio, 2:1 group
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease
Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)
The purpose is to investigate how the adsorptive capacity of the active carbon filter to carbon dioxide in an anaesthetic gas reflector (AnaConDa) is affected by adding inhaled anaesthetic agent.
- Trial name
- NCT01699802
- Testing
- Inhaled anaesthetic agent
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Region Skane
Mouth Breathing, Restrictive Breathing Pattern
Feel Breathe, Restriction Device Ventilatory Nasal
It has patented a restriction and filtering device ventilatory nasal flow FeelBreathe with the aim of increase nasal airflow resistance, therefore the objective was to examine the effects of FeelBreathe with lung ventilation and…
- Trial name
- FB (NCT01608529)
- Testing
- Feel Breathe, restriction device ventilatory nasal
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- University of Cadiz
Bronchiolitis
Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients
to assess the efficacy of inhaled furosemide in mustard gas exposed patients with acute respiratory failure
- Trial name
- NCT00512811
- Testing
- furosemide
- Where
- Iran
- Sponsor
- Baqiyatallah Medical Sciences University
Respiratory Distress Syndrome
Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure
The investigators have recently demonstrated the beneficial effects of combined high-frequency oscillation (HFO) and tracheal gas insufflation (TGI) on the respiratory physiology [1,2] of patients with severe acute respiratory…
- Trial name
- HFO-TGI-2 (NCT00637507)
- Testing
- High-frequency Oscillation and Tracheal Gas Insufflation
- Where
- 2 sites in Greece
- Volunteers
- 124 people
- Sponsor
- University of Athens
Coronavirus Infections, Pneumonia, Viral
Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID19 Infection
The scientific community is in search for novel therapies that can help to face the ongoing epidemics of novel Coronavirus (COVID-19) originated in China in December 2019.
- Conditions
- Coronavirus Infections, Pneumonia, Viral, Dyspnea
- Trial name
- NoCovid (NCT04290858)
- Testing
- Nitric Oxide
- Sponsor
- Xijing Hospital
Awareness, Anesthesia, Recall Phenomenon
Awareness in Old Aged Patients During Laryngoscopy and Intubation Using Isolated Forearm Technique
Awareness during general anesthesia - that has an incidence between 0.1% and 0.9% of cases and may be more in elderly - remains a concern for anesthesiologists.
- Conditions
- Awareness, Anesthesia, Recall Phenomenon, Inhalation; Gas
- Trial name
- NCT05019560
- Testing
- Sevoflurane, TIVA
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
General Anesthesia, Inhalation; Gas
End Tidal Anesthetic Concentration in Different Anesthesia Techniques Where Depth of Anesthesia Adjusted With Entropy
The aim of this study is to adjust the end tidal inhalation anesthetic concentration by observing the entropy value in patients who will be provided anesthesia maintenance with volatile anesthetics after applying the routine…
- Trial name
- NCT04203290
- Testing
- Bupivacaine, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University
Respiratory Insufficiency
Pathophysiology of Gas Exchange and Time Course Changes in Spontaneously Breathing Patients With Acute Respiratory Failure Due to COVID-19. A Multicenter Prospective Study.
The pathophysiology of SARS-COV-2 related respiratory disease is still poorly understood, especially in its most severe form called acute respiratory distress syndrome (ARDS).
- Trial name
- COVAQ (NCT05392062)
- Testing
- Pathophysiology of gas exchange
- Where
- France
- Volunteers
- 59 people
- Sponsor
- CHU de Reims
Pulmonary Gas Exchange, Carbon Dioxide
Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease
The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease.
- Trial name
- NCT01686984
- Testing
- Altered breath
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Region Skane
Hypoxia, Altitude, Hypoxia
Effect of Acute Hypoxia on RIght VEntRicular Function in Asthma.
More and more people are engaging in sports in the mountains, including individuals with heart or lung diseases. At the same time, such diseases are becoming more common in Switzerland.
- Conditions
- Hypoxia, Altitude, Hypoxia, Normobaric Hypoxia, Right Ventricular Function
- Trial name
- RIVER-Asthma (NCT07431580)
- Testing
- Normobaric Hypoxia
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Mona Lichtblau
Post-Acute COVID-19 Syndrome
Effect of Inhaled Hydroxy Gas on Long COVID Symptoms
The goal of this clinical trial is to see if several weeks of self-administered, home-based, treatment involving breathing hydroxy gas (a mixture of hydrogen and oxygen) for at least 2 hours a day for 3 weeks, will relieve…
- Trial name
- LCHydroxy (NCT06159296)
- Testing
- Hydroxy gas
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Oxford Brookes University
Nitrous Oxide Poisoning
Effects of Low Concentrations of Nitrous Oxide
The aim of the study is to test the effects of low concentrations of nitrous oxide on cognitive functions and reaction time in human.
- Trial name
- NCT04050267
- Testing
- Nitrous Oxide
- Where
- Czechia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Idiopathic Pulmonary Fibrosis
Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).
Idiopathic Pulmonary Fibrosis (IPF) is a progressive lung disease marked by reduced exercise capacity and activity-related breathlessness (commonly termed dyspnea).
- Trial name
- NCT05052229
- Testing
- Nitric Oxide, Medical air
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Denis O'Donnell
Accident Caused by Snow Avalanche
Snow Properties and Its Modeling for Studying Gas Exchange Under the Simulated Avalanche Snow
The aim of the study is to investigate respiratory parameters of a person in the simulated avalanche snow and consequent use of the measured data for development of a mathematical-physical model of breathing during increasing…
- Trial name
- SPAM (NCT03413878)
- Testing
- Breathing in the simulated avalanche snow
- Where
- 2 sites in Czechia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Chronic Obstructive Pulmonary Disease
QVA Mechanistic Efficacy Study (Receptor Effects, Etc)
The purpose of this study was to assess global ventilated lung volume in moderate to severe COPD patients using MRI lung imaging after treatment with QVA149 compared to placebo.
- Trial name
- NCT02634983
- Testing
- QVA149
- Where
- 3 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Novartis Pharmaceuticals
Hypoxemia, Pneumonia, Viral
Nitric Oxide Therapy for COVID-19 Patients With Oxygen Requirement
Preliminary data support the effect of Nitric Oxide (NO) on improving the oxygenation in mechanically ventilated patients and spontaneously breathing patients with COVID-19.
- Conditions
- Hypoxemia, Pneumonia, Viral, Coronavirus Infection
- Trial name
- NICOR (NCT04476992)
- Testing
- Nitric Oxide-Sessions, Nitric Oxide-Continuous and Sessions
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Anesthesia, General
Effect of Binaural Beats for Maintenance of General Anesthesia
The goal of this clinical trial is to learn about the effects of binaural beats on maintenance of general anesthesia in patients undergoing thyroidectomy without intraoperative neuromonitoring.
- Trial name
- BB (NCT06002568)
- Testing
- Silent, Binaural beats
- Where
- South Korea
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Foreign Body Aspiration, Blood Gas, Bronchoscopy
Comparison of Patients With and Without Foreign Body Aspiration After Bronchoscopy.
To compare patients under 5 years of age with foreign body aspiration and without foreign body aspiration with radiological and blood gas results.
- Trial name
- NCT04467307
- Testing
- Rigit bronchoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kahramanmaras Sutcu Imam University