BronchiolitisPhase 3NCT00512811
Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients
A Phase 3 study testing furosemide in people with Bronchiolitis, run by Baqiyatallah Medical Sciences University at 1 site in Iran.
Trial summary
to assess the efficacy of inhaled furosemide in mustard gas exposed patients with acute respiratory failure Read more about this study
- Who is it for?
- Ages 32 to 83 years, men only
- Conditions the study is for
- Bronchiolitis
- What is being tested?
- furosemide
- How many people
- Not given
- Where
- 1 siteIran
- Study dates
- Start not givento not given
- Phase
- Phase 3
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 32 to 83 years
- Men only
- Adult, Older adult
Who may be able to join
- Patients with a history of exposure to sulfur mustard with a complaint of dyspnea
Who cannot join
- A contraindication for furosemide use;
- An accompanying disease in which other drugs effective for dyspnea were used
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients: a Double-Blind Randomized Study
to assess the efficacy of inhaled furosemide in mustard gas exposed patients with acute respiratory failure
- Conditions
- Bronchiolitis
- Being tested
- furosemide
- Keywords
- furosemide, inhalation, dyspnea, spirometry, mustard gas, bronchiolitis, sulfur mustard
- Medical subject headings
- Bronchiolitis, Respiratory Aspiration, Dyspnea
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
furosemideDrug
What is being measured
The primary outcome is the main question the study is designed to answer.
effect of furosemid inhalation on dyspnea
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Aug 2007 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for BronchiolitisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase 3
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
Sponsor and investigators
- Lead sponsor
- Baqiyatallah Medical Sciences University
- Sponsor type
- University, hospital or other
- Investigators
- Mostafa Ghanei, MD, Study chair, Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Tehran, Iran
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00512811
- Sponsor's protocol ID
- 121a25
- Status last verified
- Aug 2007
- First submitted
- 7 Aug 2007
- Last updated
- 8 Aug 2007
- Results posted
- No
- Data monitoring committee
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 8 Aug 2007. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients: a Double-Blind Randomized Study
- ClinicalTrials.gov ID
- NCT00512811
- Acronym / sponsor ID
- 121a25
- Conditions
- Bronchiolitis
- Keywords
- furosemide, inhalation, dyspnea, spirometry, mustard gas, bronchiolitis, sulfur mustard
- Phase
- Phase 3
- Study type
- Interventional
- Recruitment status
- Completed
- Lead sponsor
- Baqiyatallah Medical Sciences UniversityUniversity, hospital or other
- First posted
- 8 Aug 2007 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
to assess the efficacy of inhaled furosemide in mustard gas exposed patients with acute respiratory failure
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
Who may qualify
- Ages
- 32 to 83 years
- Sex
- Male only
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Patients with a history of exposure to sulfur mustard with a complaint of dyspnea
Key exclusion criteria (2 listed)
- A contraindication for furosemide use;
- An accompanying disease in which other drugs effective for dyspnea were used
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| furosemide | Drug | – |
Primary outcome
effect of furosemid inhalation on dyspnea
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Aug 2007.
Related trials for Bronchiolitis
Active, not recruiting
Respiratory Support and Treatment for Efficient and Cost-Effective Care
Bronchiolitis
RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Belumosudil Compared With Best Available Therapy in Participants Aged 12 Years or Older With Chronic Graft-versus-host Disease
Chronic Graft Versus Host Disease
Not yet recruiting
Influence of Patient Positioning During Nasal Lavage
Acute Upper Respiratory Tract Infections, Nasal Obstruction
Recruiting
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
Aphasia, Stroke
Not yet recruiting
A New ECP Protocol for the Treatment of cGVHD
Chronic Graft Versus Host Disease
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Mostafa Ghanei, MD study chair
Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Tehran, Iran
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A Phase 3 study testing furosemide in people with Bronchiolitis, run by Baqiyatallah Medical Sciences University at 1 site in Iran.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Aug 2007. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Iran. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
What does this phase mean?
Phase 3 studies compare the treatment with the current standard treatment or a placebo in a large group, to confirm how well it works and watch for side effects.
Not every study follows the same path, and some studies (observational studies, device studies) have no phase.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
effect of furosemid inhalation on dyspnea. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Aug 2007.