Clinical trials: Infection, Coronavirus
Mild-to-Moderate COVID-19
A Clinical Study to Assess the Physiologic Effects of KB109 in Patients With COVID-19 on Gut Microbiota Structure and Function
This exploratory, open-label clinical study aims to explore the physiologic effects of KB109, a novel glycan, on adult patients with COVID-19 illness on gut microbiota structure and function in the outpatient setting.
- Trial name
- NCT04486482
- Testing
- KB109 + Self Supportive Care (SSC), Self Supportive Care (SSC) Alone
- Where
- 12 sites in United States
- Volunteers
- 49 people
- Sponsor
- Kaleido Biosciences
Covid19, Paludism
Malaria as a Protection Factor Against Severe COVID-19 (Known as SARS-COV-2) in the Democratic Republic of Congo (Palu-COVID)
In this study, the investigators will explore the reasons for the apparently lower proportion of severe COVID-19 cases in many sub-Sahara African countries.
- Trial name
- Palu-COVID (NCT05012280)
- Where
- Democratic Republic of the Congo
- Volunteers
- 238 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Coronavirus Infections
Prospective Monitoring of BNT162b2 Second Vaccination Booster Effects in Health Care Workers (HCW)
The SARS-CoV-2 virus causes severe respiratory illness and is an ongoing global pandemic. On December 12, 2020 the FDA approved Pfizer's BioNTech vaccine BNT162b2 which is a messenger RNA type of vaccine for use.
- Trial name
- NCT05516459
- Testing
- Pfizer BNT162b2 Vaccine
- Where
- Israel
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Covid-19
Clinical Application of Methylene Blue for Treatment of Covid-19 Patients
The severe acute respiratory syndrome caused by COVID-19 is now a global catastrophic event. Currently there is no approved drug or vaccine for the disease.
- Trial name
- Covid-19 (NCT04370288)
- Testing
- MCN (Methylene blue, vitamin C, N-acetyl cysteine)
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
COVID-19
Epidemiological Study on Asymptomatic Infections and Mild Illness With Covid-19 in Shanghai
this study is to clarify the epidemiological characteristics of Omicron variant infected persons in Shanghai, such as distribution characteristics, host and clinical characteristics, disease outcome and risk factors.
- Trial name
- NCT05375786
- Testing
- Vaccination completion status
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Ruijin Hospital
Covid19
Monitoring Health Care Workers at Risk for COVID-19 Using Wearable Sensors and Smartphone Technology
This prospective study of health care workers utilizes wearable sensors, surveys and symptom logs, and biospecimens in an effort to improve self-monitoring practices for COVID-19 among health care workers and to provide key data…
- Trial name
- NCT04756869
- Testing
- COVID-19 Monitoring Using Wearable Sensors and Smartphone Technology
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Covid19
Amantadine for COVID-19
Introduction: Corona virus disease 19 (COVID-19) is a devastating pandemic. By early February 2021, more than 102 million people were infected globally with more than 2.2 million reported deaths.
- Trial name
- ACT (NCT04894617)
- Testing
- Amantadine, Lactose monohydrate
- Where
- Denmark
- Volunteers
- 226 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
COVID-19
Communities Fighting COVID Return to School
San Diego State University (SDSU), a designated Hispanic-serving institution, is partnering with Sweetwater Union High School District, an independent public school district serving 90% ethnic minority and a high proportion of…
- Trial name
- NCT05150860
- Testing
- At-home COVID-19 testing, Onsite COVID-19 testing
- Where
- United States
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
SARS CoV 2 Infection
Using Vibroacoustic Therapy in a Patient With Co-infection and COVID-19
This article describes a case of successful treatment of a 59-year-old man with sepsis as a result of periprosthetic infection against the background of severe SARS-CoV-2-19, who was hospitalized for 59 days, 57 of which were in…
- Trial name
- NCT05188482
- Testing
- vibroacoustic therapy
- Where
- Kazakhstan
- Volunteers
- 1 people
- Sponsor
- Astana Medical University
COVID-19
Non-inferiority Trial on Monoclonal Antibodies in COVID-19
Currently, 3 anti-SARS-CoV-2 monoclonal antibody products have received Emergency Use Authorizations from the Italian Medicines Agency (AIFA) for the treatment of mild to moderate COVID-19 in non hospitalized patients with…
- Trial name
- MANTICO (NCT05205759)
- Testing
- Bamlanivimab Etesevimab, Sotrovimab, Casirivimab-Imdevimab
- Where
- 20 sites in Italy
- Volunteers
- 319 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
COVID-19, Myocardial Injury
Myocardial Injury and Quality of Life After COVID-19
In this observational study follow-up and dynamic observation will be conducted on the participants recovered from pneumonia caused by COVID-19.
- Conditions
- COVID-19, Myocardial Injury, Myocarditis Post Infection
- Trial name
- NCT04794062
- Where
- Russia
- Volunteers
- 119 people
- Sponsor
- Voronezh Regional Clinical Consultative and Diagnostic Center
Corona Virus Infection
Placebo Controlled Trial to Evaluate Zinc for the Treatment of COVID-19 in the Outpatient Setting
This is a randomized, double-blind, placebo-controlled trial to assess the efficacy of zinc in a higher risk COVID-19 positive outpatient population.
- Trial name
- NCT04621461
- Testing
- Zinc Sulfate 220 MG
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- St. Francis Hospital, New York
Gait, Covid19
Breathing After COVID-19
This research; It will be done to perform thoracic movement analysis of young adult individuals who have survived COVID-19 and to compare them with those without a history of COVID-19.
- Conditions
- Gait, Covid19, Thorax Anomalies
- Trial name
- NCT04944342
- Testing
- No intervention.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Trakya University
Covid19, Diabetes
REsearching Covid-19 Outcomes in Diabetes (RECODE)
The purpose of this study is to observe any changes that may occur to certain organs following a confirmed diagnosis of COVID-19 in people with and without diabetes.
- Trial name
- RECODE (NCT04805970)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Coronavirus Disease 2019, Stroke
Impact of Changes in the Use of Care and Reorganization of the Healthcare System Linked to the Covid-19 Outbreak on the Quality of Care Pathways of Patients Suffering From Acute Myocardial Infarction and Stroke in Aquitaine (AVICOVID)
The Covid-19 pandemic and its health and societal consequences raise fears of a deterioration in the management of non-Covid-19 pathologies, particularly those requiring rapid treatment.
- Conditions
- Coronavirus Disease 2019, Stroke, Acute Myocardial Infarction
- Trial name
- AVICOVID (NCT04979208)
- Where
- France
- Volunteers
- 9,218 people
- Sponsor
- University Hospital, Bordeaux
SARS CoV 2 Infection, Alveolar; Injury
The Potential Role of sRAGE, KL-6, and SP-D as Prognostic Factors in Children With COVID-19
COVID-19 causes a wide spectrum of clinical illness, from upper respiratory symptoms to severe respiratory failure and death. Several plasma biomarkers -such as IL-6, C-reactive protein (CRP), D-dimer, the…
- Conditions
- SARS CoV 2 Infection, Alveolar; Injury, Children, Pneumonia, Viral
- Trial name
- NCT05619640
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
COVID-19 Pneumonia
Efficacy and Safety of Jaktinib in Patients With COVID-19 Pneumonia.
This was a randomized, double-blind, placebo-controlled parallel study.
- Trial name
- NCT05672888
- Testing
- Jaktinib
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Pulmonary Fibrosis, COVID-19 Pneumonia
Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis
The primary purpose of this study is to determine whether the drug sirolimus reduces the likelihood of developing of pulmonary fibrosis in patients who are hospitalized with COVID-19 pneumonia.
- Conditions
- Pulmonary Fibrosis, COVID-19 Pneumonia, Long COVID
- Trial name
- NCT04948203
- Testing
- Sirolimus
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Chicago
Coronavirus Disease 2019
Huashi Baidu Granule in the Treatment of Pediatric Patients With Mild Coronavirus Disease 2019
The investigators conducted a single-center, open-label, parallel-group randomized controlled trial to assess the efficacy and safety of a Chinese herb compound granule Huashi Baidu granule (HSBDG) in pediatric patients with…
- Trial name
- NCT05501288
- Testing
- Huashi Baidu granule, compound pholcodine oral solution
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Shanghai Children's Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.