Clinical trials: Infant, Premature Development
Periodontitis, Autism
Maternal Oral Therapy to Reduce Obstetric Risk Kids
The principal objective was to conduct a 5 year; multi-center, observational follow-up study enrolling infants born to mothers who participated in the MOTOR clinical trial to determine the effects of maternal periodontal therapy…
- Conditions
- Periodontitis, Autism, Premature Infants
- Trial name
- MOTORKids (NCT03423836)
- Where
- 4 sites in United States
- Volunteers
- 331 people
- Sponsor
- University of North Carolina, Chapel Hill
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Music Therapy
Premature Family Music Therapy Intervention (PFMI)
The music therapy intervention it is dedicated to premature baby and their family at the Neonatal Intensive Care Unit (NICU)of the Woman-Child department "Hospital Del Ponte".
- Trial name
- PFMI (NCT04335240)
- Testing
- Premature family music therapy intervention to support parenting, attachment bond and preterm development
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Extreme Prematurity, Neurodevelopmental Abnormality
Osteopathic Manipulative Medicine to Reduce Developmental Delays
This randomized clinical trial seeks to determine if osteopathic manipulative medicine (OMM) increases the likelihood of improved neurodevelopmental outcomes as estimated by the Test of Infant Motor Performance (TIMP).
- Trial name
- NCT04652063
- Testing
- Osteopathic Manipulative Medicine
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Premature Infant Disease
A Randomized Controlled Trial to Evaluate the Effect of White Noises and Parental Voices As Protectors Against Noise Damage in a Neonatal Intensive Care Unit
The goal of this Randomized Controlled Trial is to test the efficacy of listening to white noises and parental voices against environmental noise damage in premature babies admitted to the Newborn Intensive Care Unit.
- Trial name
- NCT06150404
- Testing
- White Noises and Maternal and/or Paternal voices
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Giannina Gaslini
Bronchopulmonary Dysplasia
Preservation of Blood in Extremely Preterm Infants
Current clinical protocols for blood sampling and analyses in extremely preterm infants rely on an infrastructure adapted to and developed for adult medicine.
- Trial name
- LIM (NCT04239690)
- Testing
- Micromethods for blood sample analysis
- Where
- Sweden
- Volunteers
- 201 people
- Sponsor
- David Ley
Very Preterm Maturity of Infant
Prematurity at the Limit of Viability
Advancements in perinatal care have significantly improved the survival of extremely premature infants, establishing a viability threshold below 25 weeks' gestational age (GA).
- Trial name
- PRELIVIA (NCT06391476)
- Testing
- Study of the evolution of a cohort of children born between 22 and 25 weeks gestational age
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Premature Infant Disease, Development, Infant
Impact of Reading on Endogenous Oxytocin System of Preterm Infants
The purpose of this study is to learn how early language exposure may be related to changes in DNA in parents and their premature infants.
- Trial name
- NCT05412524
- Testing
- reading
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Virginia
Preterm Birth, Premature Birth
Exposure to Plasticisers in the Neonatal Intensive Care Unit
Neonatal intensive care relies on indwelling plastic medical devices fundamental in respiratory support, intravenous catheterization, and nutrition.
- Conditions
- Preterm Birth, Premature Birth, Neurodevelopmental Disorders, Pulmonary Disease
- Trial name
- PLASTIC-NICU (NCT05404815)
- Where
- Belgium
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Congenital Heart Defect, Respiratory Distress Syndrome in Premature Infant
Neonatal Cardio-Pulmonary Outcome Measure
Neonatal Cardio-Pulmonary outcome measure (N-COM) will be used to assess the overall status of pulmonary and cardiac vascular system of neonates in Neonatal Intensive Care Unit (NICU).
- Trial name
- N-COM (NCT04324957)
- Testing
- Neonatal cardio-pulmonary outcome measure used to assess cardio-pulmonary status
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Asir John Samuel
Preterm Infants
Socio-Emotional Development in Preterm Infants
With advances in medicine and medical technology, premature infants born as early as 24 weeks of gestation and with birth weight less than 1000 grams are surviving today. Preterms are born with immature biological systems.
- Trial name
- NCT00917475
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hearing Loss, Mental Retardation
Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes.
The aim of this study is to investigate short and long term consequences from early postnatal HCMV infection transmitted via human milk in very preterm infants (birth weight < 1500 g or gestational age < 32 weeks).
- Conditions
- Hearing Loss, Mental Retardation, Microcephaly, Chorioretinitis
- Trial name
- NCT01151462
- Where
- Norway
- Sponsor
- Oslo University Hospital
Impaired Psychomotor Development
Omega-6/Omega-3 Ratio and Neural Development in Preterm Infants.
It's known that Docosahexaenoic acid DHA and all Polyunsaturated Fatty Acids PUFA are important in neurodevelopment of term and preterm infants.
- Trial name
- NCT02339727
- Testing
- Preterm infants formula
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ayham alshweki
Infant Development, Cerebral Palsy
Cerebrolysin and Neurodevelopment in Preterm Infants
The overall aim of the study is to assess the effect of Cerebrolysin on physical and mental development of preterm infants by Denver Scale II at different ages of 5, 7 and 12 months
- Conditions
- Infant Development, Cerebral Palsy, Preterm Infant
- Trial name
- NCT03506841
- Testing
- Cerebrolysin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Children Hospital
Feeding; Difficult, Newborn, Premature Infant Disease
Psychometric Properties of the SMART Feeding Tool
This observational study aims to evaluate the psychometric properties of a new infant feeding tool called "SMART Tool" in the neonatal intensive care unit. The main questions it aims to answer are: 1.
- Conditions
- Feeding; Difficult, Newborn, Premature Infant Disease, Dysphagia of Newborn, Nurse's Role
- Trial name
- NCT05729828
- Where
- 4 sites in United States
- Volunteers
- 76 people
- Sponsor
- Wake Forest University Health Sciences
Premature Infants
Post-Discharge Growth and Development of Infants Who Received Targeted Fortification in the NICU
Extremely low birth weight (ELBW) infants are at risk for slow growth, metabolic abnormalities, and poor neurodevelopmental outcomes.
- Trial name
- NCT04190875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Premature Birth
Effectiveness of Music Therapy on the Development of Preterm Neonates
Pragmatic, randomized controlled clinical trial with blinding of the evaluator, performed in order to estimate the effectiveness, six (6) months after hospital discharge, of music therapy on the intra-hospital evolution and…
- Trial name
- EMT-DRNP (NCT02948491)
- Testing
- Music therapy
- Where
- Colombia
- Volunteers
- 90 people
- Sponsor
- Universidad Manuela Beltrán
Preterm Infant, Feeding Behavior
A Cue-based Developmental Approach Toward the Preterm Infants During Feeding Transition Period
The coordination of sucking, swallowing, and breathing during the transition from gavage to oral feeding is a challenge for preterm infants.
- Conditions
- Preterm Infant, Feeding Behavior, Feeding Patterns
- Trial name
- NCT03755999
- Testing
- The premature infant oral motor intervention (PIOMI)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng-Kung University Hospital
Premature Infant, Developmental Delay
A Parent Administered Sensorimotor Intervention and Developmental Outcome of Preterm Infants
Advances in medical technologies over the last three decades have increased survival rates in infants born preterm . Preterm infants are at high risk of developing developmental delays.
- Trial name
- NCT03836326
- Testing
- Sensorimotor intervention, Control, Story telling attention refocusing intervention
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Dr. Sandra Fucile
Developmental Delay
18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study
The purpose of this study is to examine differences in the long-term effects of immediate versus delayed cord clamping at birth on developmental outcomes of our study infants at 18-22 months corrected age.
- Trial name
- 18mo (NCT01426698)
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Rhode Island