Clinical trials: Induced
Cataract, Refractive Surgery
Refractive Change Induced by 2.8-mm Corneal Incision
The investigators' purpose is to study the induced refractive change caused by different 2.8-mm corneal incision locations in phacoemulsification, because the investigators hypothesize that the effect may be different for nasal…
- Conditions
- Cataract, Refractive Surgery, Astigmatism
- Trial name
- CINPHA (NCT00742950)
- Testing
- Nasal 2.8-mm corneal incision, Temporal 2.8-mm corneal incision, Superior 2.8-mm incision
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Axillary Hyperhidrosis
Miradry Treatment for Focal Axillary Hyperhidrosis
Primary hyperhidrosis is a pathological condition characterized by the idiopathic and excessive secretion of sweat beyond normal physiological demand and is localized at particular foci such as the face, axilla, palms of the…
- Trial name
- MiraDry Tx (NCT02295891)
- Testing
- MiraDry ®
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Johns Hopkins University
Acute Myeloid Leukemia
Refining the Role of Mid-induction Bone Marrow Biopsy in Acute Myeloid Leukemia: A Pilot Study
The purpose of the study is to observe the outcomes of patients with acute myeloid leukemia who do not receive an immediate second round of chemotherapy after undergoing a standard mid-induction bone marrow biopsy.
- Trial name
- NCT06323590
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Neurotoxicity
Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer Patients
The purpose of this study is to determine whether monosialoganglioside are effective in the prevention of neurotoxicity induced by albumin-bound paclitaxel chemotherapy in lung cancer patients, and improve the quality of life of…
- Trial name
- NCT02500810
- Testing
- monosialoganglioside
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Peking University Cancer Hospital & Institute
Opioid Use Disorder, OAT
Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use Disorder
The goals of this sub-study is to assess CB1R availability in early abstinent individuals with OUD (following opioid agonist therapy - OAT stabilization) and in matched healthy controls.
- Trial name
- NCT07800520
- Testing
- [11C]OMAR
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Yale University
Substance Abuse
Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education
Our primary goal is to conduct a pilot study of the effects of a new potential strategy for youth substance abuse prevention - science-based drug education integrated into the high school science curriculum.
- Trial name
- NCT00612482
- Testing
- drug prevention curriculum
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pregnancy, Preeclampsia
Effects of Progressive Muscle Relaxation Exercise and Finger Grip Exercise on Stress, Anxiety, Fatigue, Sleep Quality, and Physiological Parameters in Pregnant Women With Preeclampsia
The aim of this study is to examine the effects of progressive muscle relaxation exercise and finger grip exercise on stress, anxiety, sleep quality, fatigue and physiological parameters in preeclamptic pregnant women.
- Trial name
- NCT07630623
- Testing
- Progressive Muscle Relaxation Exercise, Finger Grip Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hatice Nur Nefes Pala
Cocaine Abuse, Cocaine-Related Disorders
Medications for Stopping Cocaine Dependence and Preventing Relapse
Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found.
- Trial name
- NCT00218023
- Testing
- Modafinil, Levodopa/Carbidopa, Naltrexone HCl
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Neuropathic Pain
Medicinal Cannabis for Painful HIV Neuropathy
The purpose of this study is to determine if medicinal cannabis (marijuana) is safe and effective for treating pain in individuals with HIV-associated distal, sensory-predominant polyneuropathy (DSPN).
- Trial name
- NCT00255580
- Testing
- Smoked cannabis
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Center for Medicinal Cannabis Research
Opioid Use Disorder, Alcohol Use Disorder
Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study
The purpose of this study is to learn how best to treat substance use disorders in an HIV clinic setting. Specifically, the purpose of this pilot study is to learn if extended-release naltrexone (XR-NTX) would be a feasible and…
- Trial name
- CHOICES (NCT01908062)
- Testing
- Extended Release Naltrexone, Treatment As usual
- Where
- 2 sites in United States, Canada
- Volunteers
- 51 people
- Sponsor
- Oregon Health and Science University
Iron-deficiency, Inflammation
Iron and Muscular Damage: FEmale Metabolism and Menstrual Cycle During Exercise
This project is an observational controlled randomized counterbalance study. One hundred and three physically active and healthy women were selected to participate in the IronFEMME Study, of which 57 were eumenorrheic, 30 were…
- Conditions
- Iron-deficiency, Inflammation, Exercise Induced Iron-deficiency, Exercise Induced Muscle Damage
- Trial name
- IronFEMME (NCT04458662)
- Testing
- Interval running protocol / eccentric-based resistance exercise protocol
- Where
- Spain
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Aging, Balance Deficits
Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems
The goal of this study is to learn if manipulating the brain using magnets works to treat balance impairment, a major cause of falls, in older adults with balance problems.
- Trial name
- NCT06779188
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Weinberg Medical Physics LLC
Solid Cancer, Gastric (Cardia, Body) Cancer
Impact of CES1 Genotype on Capecitabine Exposure in Cancer Patients
In this study, the drug capecitabine is investigated. Capecitabine is commonly used to treat breast, colon, and stomach cancers. Capecitabine is taken in tablet form.
- Conditions
- Solid Cancer, Gastric (Cardia, Body) Cancer, Esophageal Cancer, Colorectal Cancer (CRC)
- Trial name
- ESCAPE (NCT07114627)
- Testing
- Blood sampling for pharmacokinetics
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Erasmus Medical Center
Advanced Breast Cancer
Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Breast Cancer
This is a phase II Randomized comparison clinical trial of activated CIK armed with anti-CD3-MUC1 bispecific antibody for advanced breast cancer.
- Trial name
- NCT03524261
- Testing
- Activated CIK and CD3-MUC1 Bispecific Antibody in Treating Breast Cancer, cryotherapy
- Where
- China
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Bronchopulmonary Dysplasia
Mesenchymal Stem Cell Therapy for Bronchopulmonary Dysplasia in Preterm Babies
Bronchopulmonary Dysplasia (BPD) is the most frequent disease related to a premature birth, 15-50% of very low birth newborns (<1500 gr.) will develop BPD.
- Trial name
- NCT02443961
- Testing
- Mesenchymal Stem Cell (MSC) therapy
- Where
- 4 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Carcinoma, Non-Small-Cell Lung
Atezolizumab Immunotherapy in Patients With Advanced NSCLC
Phase II trial of induction immunotherapy with atezolizumab for patients with unresectable stage IIIA and IIIB NSCLC eligible for chemoradiotherapy with curative intent.
- Trial name
- NCT03102242
- Testing
- Atezolizumab
- Where
- 13 sites in United States
- Volunteers
- 64 people
- Sponsor
- Alliance Foundation Trials, LLC.
Chronic Kidney Disease, Cardiovascular Disease
Mechanisms of Chronic Kidney Disease (CKD)-Induced Foam Cell Formation
There is currently little understanding of macrophage cholesterol homeostasis and foam cell formation across the spectrum of CKD.
- Trial name
- NCT01671605
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Vanderbilt University Medical Center
Substance Use Disorders, Alcohol Use Disorder
Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic
"Gold-standard" medications for opioid use disorder (MOUD) treatment combines FDA-approved medications, primarily methadone and buprenorphine, with behavioral therapies to provide "whole-patient" treatment.
- Conditions
- Substance Use Disorders, Alcohol Use Disorder, Opioid Use Disorder
- Trial name
- IMPACT (NCT07232641)
- Where
- United States
- Volunteers
- 185,810 people
- Sponsor
- Boston University
Opioid-Related Disorders
Neurobiology of Opioid Dependence: 3 - 3
The purpose of this study is to study the effects of cycloserine on naloxone-precipitated opiate withdrawal.
- Trial name
- NCT00000194
- Testing
- Cycloserine
- Where
- United States
- Sponsor
- Yale University
Periodontal Inflammation
The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups
the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients
- Trial name
- NCT06140394
- Testing
- diode laser, non surgical scaling
- Where
- 2 sites in Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.