Clinical trials: Individuality
Bronchiectasis, Quality of Life
Evaluating the Effects of Traditional Chinese Medicine by N-of-1 Trials
Treatment based on syndrome differentiation is the essence of traditional Chinese Medicine(TCM) and forms the individualized treatment.
- Conditions
- Bronchiectasis, Quality of Life, Traditional Chinese Medicine, Sputum
- Trial name
- NCT03147443
- Testing
- Individualized Decoction, Tested drug minus heat-clearing herbs
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Individuality, Asthma
Vaccination Response in Individual Monozygotic Twins
Respiratory viruses are known to be risk factors for asthma (e.g respiratory syncytial viruses, RSVs, and Human Rhinoviruses, HRVs, may induce bronchiolitis, and wheezing illnesses respectively).
- Conditions
- Individuality, Asthma, Immune System and Related Disorders
- Trial name
- NCT02296359
- Testing
- Influenza Vaccination
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Sleep, Diabetes
Individual Differences in Diabetes Risk: Role of Slow WaveSleep
This study will examine the relationship between the amount of slow wave sleep (deep sleep) and the ability of the body to bring the blood sugar level to a normal range after receiving glucose.
- Trial name
- NCT00989378
- Testing
- baseline study
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Healthy Volunteers
Manipulating Social Percepts During fMRI
This study will investigate the use of real-time fMRI to change how participants perceive social information.
- Trial name
- NCT07528378
- Testing
- Real-time fMRI: Brain-state- triggered trials, Real-time fMRI: Covert neurofeedback
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Individual Difference, Food Sensitivity
Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Brief Summary: This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04302779
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Reading
Emotions, Anhedonia
Geolocation Positional System (GPS) Experience
The purpose of this study is to use smartphone technology to capture individual location emotional and cognitive data, to examine how real-world behaviors thoughts, emotions, and brain activity are related to one another.
- Conditions
- Emotions, Anhedonia, Depression
- Trial name
- NCT05991713
- Testing
- Modifying Exploration
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Obesity
CD36 and Human Fat Taste Perception
The purpose of this study is to determine the effect of common human variants in in taste related genes, such as CD36 gene, a putative fat taste receptor, affect fat taste perception.
- Trial name
- FATYP (NCT02699567)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Drug Addiction, Vulnerability to Substance Addiction
Individual Differences in Reward and Impulse Control
Background: The risk for becoming addicted to drugs varies among individual, even those using similar drugs in a similar way. It is not known why some people become addicted and others do not.
- Trial name
- NCT01621607
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Individuality, Healthy Subjects
Milieu Intérieur Collection - Genetic & Environmental Determinants Of Immune Phenotype Variance
The purpose of this study is to assess the determinants of immunologic variance within the general healthy population.
- Trial name
- MI (NCT03905993)
- Volunteers
- 956 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Sleep, Diabetes
Individual Differences in Diabetes Risk: Role of Sleep Disturbances
The hypothesis for this study is that some individuals may be at much higher risk to develop type 2 diabetes and that the individual diabetes risk will be predicted by the individual level of slow wave sleep activity (SWA).
- Trial name
- NCT00989976
- Testing
- normal sleep times, bedtime restriction
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Autism Spectrum Disorder (ASD
Effectiveness of DIR/Floortime™ in Children With Autism Spectrum Disorder
This randomized controlled trial evaluates the efficacy of Integrated DIR/Floortime™ in improving functional emotional development and adaptive behavior in children aged 4-12 years with Autism Spectrum Disorder (ASD).
- Trial name
- DIR-ASD (NCT07758465)
- Testing
- DIR/Floortime, Standard therapy
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Fatima Tabassum
Appetite Self-regulation, Pediatric Obesity
Food Form & Energy Intake
This study primarily aims to examine how food presented in various forms (i.e., solid, semi-solid, and liquid) affects children's ability to self-regulate energy intake at a subsequent meal.
- Trial name
- NCT05258097
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Penn State University
Alcoholism
Chicago Social Drinking Project
This study attempts to elucidate the factors that contribute to escalation and maintenance of excessive ethanol drinking in young adults by: 1.
- Trial name
- CSDP (NCT00961792)
- Testing
- Ethanol, Diphenhydramine, Caffeine
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Chicago
Individual Difference
Increasing Individualism and Collectivism
An online survey is conducted on MTurk populations from India and USA. Participants were assigned either a condition with primes of individualism or one with primes of collectivism, before responding to a scale on culture and…
- Trial name
- NCT03429725
- Testing
- Online prime (statements writing), Online prime (circling), Online prime (Sumarian Warrior)
- Where
- Singapore
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Type 2 Diabetes Mellitus in Obese, Type 2 Diabetes
LCMD for Type 2 Diabetes Remission: Evaluation of Effectiveness and Exploration of Individual Differences
Type 2 diabetes (T2DM) has become a major public health problem. Achieving remission (HbA1c<6.5% without glucose-lowering medications) has recently become a new treatment goal.
- Trial name
- LCMD (NCT06442150)
- Testing
- Low-Calorie Medicine Diet, Low-Calorie Diet
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Surgery, Individuality
Association of CYP3A4 rs2242480 With Sufentanil Plasma Concentration and PCA Consumption
This study was designed for exploring the association of cytochrome P450 3A4 rs2242480 polymorphism with metabolism of sufentanil in Chinese patients receiving upper abdominal surgery，to provide evidence for genetic prediction of…
- Trial name
- NCT02070614
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Xianwei Zhang
Bronchiectasis, Quality of Life
A Series of N-of-1 Trials of Traditional Chinese Medicine Based on Bayesian Method
The guiding role of parallel randomized controlled trials in clinical practice is limited due to the insufficiency of individual information.
- Conditions
- Bronchiectasis, Quality of Life, Traditional Chinese Medicine, Sputum
- Trial name
- NCT04601792
- Testing
- Individualized Decoction, Tested drug minus heat-clearing herbs
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Opioid Sensitivity, Individual Difference
A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans
Within-subject, double-blind, placebo-controlled examination of opioid abuse potential in healthy individuals as a function of A118G SNP on the OPRM1 gene.
- Conditions
- Opioid Sensitivity, Individual Difference, Abuse Opioids
- Trial name
- NCT02360371
- Testing
- Within-subject test of blinded study medication
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Knee Osteoarthritis (OA), Chronic Pain
Individual Differences in Gait and Osteoarthritis Pain
The goal of this observational study is to look at inter-individual differences in knee osteoarthritis (OA) walking pain and performance.
- Conditions
- Knee Osteoarthritis (OA), Chronic Pain, Chronic Knee Pain
- Trial name
- INDIGO (NCT07308873)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Healthy
Individual Differences in Cognitive Control Predict Real-time fMRI Neurofeedback Performance
The goal of this study is to investgate whether individual differences of cognitive control capacity could predict neurofeedback performance and the behavioral effects resulting from successful anterior insula regulation via…
- Trial name
- NCT07211269
- Testing
- Real-time fMRI neurofeedback training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China