Clinical trials: Individual Psychiatric Disorder
Anorexia Nervosa
Heart Rate Sensing and Response in Persons With Anorexia Nervosa
There are two major goals of this investigation. First, to develop pilot data to justify a larger randomized clinical trial of an intervention designed to train interoceptive signals (IS) and interoceptive responsivity (IR) in…
- Trial name
- NCT02579018
- Testing
- One hour supervised exercise session
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Mild Cognitive Impairment
A Comparative Study of Brain Structure and Amyloid Load in MCI Patients
Older people with DM are at greater risk of cognitive decline than their counterparts with DM. Cognitive impairment in older people with DM may be associated with non-AD related brain atrophy and white matter disease.
- Trial name
- NCT03773185
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
Psychotic Disorders, Schizophrenia
Medication Adherence in Older People With Psychosis
This study will determine whether Medication Adherence Therapy (MAT) can improve medication adherence and lower the risk of rehospitalization in older patients with psychosis.
- Trial name
- NCT00071604
- Testing
- Medication Adherence Therapy, Friendly Support Group
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Veterans Medical Research Foundation
Hepatitis C
Surveillance and Treatment of Prisoners With Hepatitis C
The purpose of the study is to assess how feasible it is to treat and prevent the transmission of Hepatitis C in the prison setting to achieve substantial reductions in the incidence and prevalence of Hepatitis C.
- Trial name
- SToP-C (NCT02064049)
- Testing
- Sofosbuvir/velpatasvir
- Where
- 4 sites in Australia
- Volunteers
- 3,692 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Autism Spectrum Disorder
Development and Validation of a System for the Anticipation of Challenging Behaviors
Most people with autism spectrum disorder (ASD) present at least one form of challenging behavior (CB). Self-injurious, aggressive, and disruptive CBs linked with social interaction, community-based service exclusion, and a life…
- Trial name
- NCT05340608
- Testing
- Smart, non-invasive shirt - Physiological parameters, Smart, non-invasive shirt - Relation with challenging behaviors, Smart, non-invasive shirt - Proof of Concept
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ariel University
Osteoporosis, Cognitive Decline
Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People
It is hypothesized that vitamin B12 and folic acid supplementation reduces the number of incident fractures. The proposed study, a randomized placebo-controlled intervention trial, compares daily supplementation with folic acid…
- Trial name
- B-PROOF (NCT00696514)
- Testing
- Vitamin B12, folic acid, Vitamin D3
- Where
- 3 sites in Netherlands
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Psychiatric Disorders
Comparing Telepsychiatry and In-person Outcomes
Psychiatric consultation and short-term follow-up will produce equivalent clinical outcomes and be less costly when provided via videoconferencing (telepsychiatry) than when provided in-person.
- Trial name
- NCT00292058
- Testing
- Videoconference equipment (telepsychiatry)
- Where
- Canada
- Volunteers
- 495 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Generalised Anxiety Disorder
Trial of Sertraline Versus Cognitive Behaviour Therapy for Generalised Anxiety
Generalised Anxiety Disorder (GAD) is common, causes unpleasant symptoms and impairs people's functioning. It is often chronic and may be accompanied by depression and other anxiety disorders.
- Trial name
- ToSCA (NCT02347033)
- Testing
- Sertraline, Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University College, London
Borderline Personality Disorder
Physical Activity in People With Borderline Personality Disorder (PABORD)
The aim of this Randomised Controlled Trial (RCT) is to test the effects of a structured physical activity (PA) program on symptoms in female outpatients aged 18 to 40 years with a diagnosis of Borderline Personality Disorder…
- Trial name
- PABORD (NCT06461104)
- Testing
- Structured Physical Activity Programme, Psychoeducational Programme
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Behavior, Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric…
- Conditions
- Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- CABxtime (NCT06705179)
- Testing
- Behavioral task performance
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- California Institute of Technology
Schizophrenia
The New Strategy for Pharmacological Treatment in People With Schizophrenia
Switching from Risperidone to Aripiprazole in early stage of pharmacotherapy will demonstrate the same efficacy as compared to risperidone continuation treatment in the treatment of schizophrenia.
- Trial name
- NCT00352339
- Testing
- Rispridoen and Aripiprazole, Risperidne, Abilify
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Inje University
Schizophrenia
Exploratory Study of a Digital Therapeutics in People With Schizophrenia
CT-155 is a novel prescription digital therapeutic (PDT) being developed by Click Therapeutics, Inc. (Click) and Boehringer Ingelheim (BI) using an interactive, software-based intervention to treat schizophrenia
- Trial name
- NCT05438160
- Testing
- Clinical Learning Study smartphone app (i.e., the study app)
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Click Therapeutics, Inc.
Loneliness
Reduce Loneliness in Care Partners of Persons With AD/ADRD
More than 60% of care partners of persons with AD/ADRD report feeling lonely. Building on the existing evidence that increasing meaning and purpose in life is a strong predictor of decreased loneliness, interventions to reduce…
- Trial name
- NCT05460494
- Testing
- RELOAD-C
- Where
- 4 sites in United States
- Volunteers
- 96 people
- Sponsor
- Northwell Health
Stress Disorders, Post-Traumatic
An Integrated Online Program Using Psychoeducation and Expressive Writing for People With Probable Post-traumatic Stress Disorder and Coexisting Dissociative Symptoms
Objectives: To evaluate the feasibility, acceptability, safety, and preliminary effects of an integrated online program with psychoeducation and expressive writing components for people with probable post-traumatic stress…
- Trial name
- NCT06523023
- Testing
- An integrated online program
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Gambling, Pathological
Computer-based Training (Retraining) for People With Gambling Problems
The study examines the efficacy and acceptance of a computer-based training program for individuals with problematic or pathological gambling behavior.
- Trial name
- Retraining (NCT03460288)
- Testing
- Retraining (AAT)
- Where
- Germany
- Volunteers
- 141 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dementia
ACT for Carers of People With Dementia
Background: Acceptance and Commitment Therapy (ACT) is a therapy that helps people to notice and accept difficult thoughts and emotions. ACT also helps people to identify what they value in life (e.g.
- Trial name
- NCT02991183
- Testing
- ACT
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Multiple Sclerosis, Insomnia
A Digital Therapeutic to Improve Insomnia in Multiple Sclerosis: A Randomized Controlled Trial.
The goal of this randomized controlled trial is to test the effectiveness of digital cognitive behavioral therapy for insomnia (dCBT-I) compared with digital patient education about insomnia for people with Multiple Sclerosis…
- Trial name
- NorseMS (NCT06113666)
- Testing
- Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I), Digital patient education about insomnia (PE)
- Where
- Norway
- Volunteers
- 550 people
- Sponsor
- St. Olavs Hospital
Bipolar Disorder
FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder
This study will assess the effects of bipolar disorder on brain activity and will determine if medication changes the brain activity in people with bipolar disorder.
- Trial name
- NCT00596622
- Testing
- Lithium
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Schizophrenia
Schizophrenia and Genetic Counseling
This research is designed to investigate the perceptions and opinions of individuals who either have schizophrenia or who have a family member with schizophrenia, in relation to genetic counseling.
- Trial name
- NCT00111202
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Lawrence College
Binge Drinking
Afferent Neurocardiac Signals, Cue Reactivity, and Cognitive Control
Conscious attempts to regulate alcohol use are often undermined by automatic attention and arousal processes activated by alcohol cues, as well as by diminished ability to inhibit in-the-moment behaviors.
- Trial name
- NCT05369169
- Testing
- Resonance breathing, Low demand cognitive task
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
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