Clinical trials: Incision
Surgical Wound Infection
The Use of a Silver Containing Dressing (Acticoat) on Wound Complication Rates Post Elective Cesarean Section
The purpose of this study is to determine the effect of a silver containing dressing (Acticoat Post-Op) compared to a standard dressing (OpSite PostOp) on post elective cesarean section wound complications in obese women (BMI…
- Trial name
- NCT02288884
- Testing
- Acticoat PostOp, OpSite PostOp
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Surgical Wound Infection
A Randomized Controlled Trial Exploring the Ability of Negative Pressure Wound Therapy (NPWT) to Reduce Colorectal Surgical Site Infections (SSI)
The study will explore the ability of negative pressure wound therapy (Prevena dressing) to reduce post operative superficial surgical site infection rate in elective colorectal surgery.
- Trial name
- NCT02348034
- Testing
- Prevena Dressing
- Where
- 3 sites in Canada
- Volunteers
- 126 people
- Sponsor
- University of Saskatchewan
Hernia, Ventral, Incisional Hernia
A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair
The objective of this study is to collect additional data on safety, performance and effectiveness of Phasix™ ST in subjects receiving laparoscopic ventral or incisional hernia repair at high risk for surgical site occurrence…
- Trial name
- ATLAS (NCT02712398)
- Testing
- Phasix™ ST
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
Postoperative Pain, Abdominal Surgery by Laparotomy
Rectus Sheath Block as an Adjunct to General Anesthesia for Midline Laparotomy Pain
This study evaluates whether adding an ultrasound-guided rectus sheath block (RSB) to general anesthesia can improve pain control after midline laparotomy.
- Trial name
- RSB-MIDLINE (NCT07393763)
- Testing
- Ultrasound-guided rectus sheath block
- Where
- Indonesia
- Volunteers
- 46 people
- Sponsor
- Udayana University
Surgical Incision
BandGrip® Closure of Surgical Incisions Following Arthroscopic Surgery
A single-arm, prospective, unblinded, post marketing, single center study using BandGrip to close incisions post arthroscopic shoulder surgery.
- Trial name
- NCT03644316
- Testing
- BandGrip skin closure device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- BandGrip
Surgical Site Infection, Vaginal Cuff Cellulitis
Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal Clindamycin
This study seeks to determine ways to reduce the hospitals surgical site infection rate during hysterectomy operations.
- Conditions
- Surgical Site Infection, Vaginal Cuff Cellulitis, Bacterial Vaginosis
- Trial name
- NCT07888101
- Testing
- Clindamycin Vaginal Gel
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Baylor Research Institute
Incisional Hernia, Emergency Midline Laparotomy
Risk Factors of Incisional Hernias After Emergency Midline Laparotomy
The aim of this study is to identify risk factors for the development of incisional hernias in emergency midline laparotomies.
- Trial name
- INCISE (NCT05509452)
- Where
- Denmark
- Sponsor
- Herlev Hospital
Incisional Hernia
Prophylactic Mesh in Cytoreductive Surgery
Evaluate the effectiveness of mesh reinforcement in high-risk patients to prevent incisional hernia.
- Trial name
- NCT03953365
- Testing
- Prophylactic Mesh
- Volunteers
- 66 people
- Sponsor
- Hospital Universitario Fundación Alcorcón
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Colorectal Cancer
Interrupted 'Figure-of-X' Versus Continuous Suturing Technique for Abdominal Wall Closure in Colorectal Laparotomies
This prospective randomized comparative study aims to evaluate whether interrupted figure-of-X fascial closure reduces the incidence of burst abdomen compared with continuous suturing in patients undergoing open colorectal…
- Trial name
- X-CLOSURE (NCT07585344)
- Testing
- Interrupted 'Figure-of-X' Suturing Technique, CONTINUOUS AMSS CLOSURE
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Islamabad Medical and Dental College
Surgical Site Infection, Surgical Wound Infection
Antibacterial-coated Sutures at Time of Cesarean
Abdominal closure with antibacterial-coated sutures has been shown to reduce wound infections after a number of surgical procedures, but none of the previous trials included cesarean delivery.
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Cesarean Section; Infection, Cesarean Section Complications
- Trial name
- ASTC (NCT03386240)
- Testing
- Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures), Vicryl, monocryl, PDS (not coated with triclosan)
- Where
- United States
- Volunteers
- 1,169 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Arterial Obstructive Diseases
Trial Using Integuseal as Microbial Sealant for Arterial Bypass Surgery on Lower Extremities
The purpose of this study is to prove a reduction of postoperative wound infections after direct preoperative use of a microbial sealant in the form of Integuseal for vascular procedures on lower extremities.
- Trial name
- ITT (NCT00940979)
- Testing
- Application of Integuseal sealant
- Where
- 3 sites in Netherlands
- Volunteers
- 450 people
- Sponsor
- Rijnstate Hospital
Hernia, Ventral, Ventral Incisional Hernia
Use of Mosquito Net Mesh for Ventral Hernia Repair
It´s a pilot study, randomized, realized in the Central Hospital "Dr. Ignacio Morones Prieto", SLP, Mexico. Hypothesis: The polyethylene mesh is secure in open ventral repair.
- Trial name
- NCT03324854
- Testing
- Rives technique, Drainage, Prophylactic
- Volunteers
- 20 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Surgical Site Infection
SSI Rates in Patients Undergoing Mastectomy Without Reconstruction- A Multicenter, Double-blinded RCT.
Breast cancer is the second most prevalent malignancy in the world and an important component of treatment warrants surgical procedures such as mastectomy.
- Trial name
- NCT04577846
- Testing
- Cephalexin 500 MG
- Where
- 3 sites in Pakistan
- Volunteers
- 384 people
- Sponsor
- Aga Khan University
Pain, Surgical Wound
Preemptive Paracetamol for Postoperative Pain
The purpose of this study is to test whether a dose of paracetamol given before surgical incision is more effective at reducing postoperative pain and analgesic consumption in cervical spine surgery versus a dose given at the end…
- Trial name
- PPPP (NCT02425254)
- Testing
- Intravenous paracetamol, Intravenous saline 0.9%
- Volunteers
- 50 people
- Sponsor
- University of Nottingham
Gastrointestinal Tumors, Surgical Wound Infection
Non-Dressing vs. Routine Dressing Change After Gastrointestinal Cancer Surgery
The goal of this randomized non-inferiority trial is to evaluate whether omitting postoperative wound dressings is noninferior to routine dressing changes in patients undergoing gastrointestinal cancer surgery.
- Conditions
- Gastrointestinal Tumors, Surgical Wound Infection, Pain, Postoperative
- Trial name
- Dressing (NCT06263205)
- Testing
- Non-Dressing of Surgical Wound, Regular Dressing Change of Surgical Wound
- Where
- 4 sites in China
- Volunteers
- 1,138 people
- Sponsor
- Fudan University
Drug Resistance, Bacterial, Postoperative Wound Infection
Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery
The aim of the present study is to evaluate a new technique for prevention of sternal wound infection consisting of local application of collagen-gentamicin in addition to routine i.v. antibiotic prophylaxis.
- Trial name
- LOGIX (NCT00484055)
- Testing
- Local application of collagen-gentamicin, Fixation of the sternotomy with more than six wires
- Where
- 2 sites in Sweden
- Volunteers
- 1,358 people
- Sponsor
- Region Örebro County
Complications; Cesarean Section
Scalpel vs Diathermy in Repeat Cesarean Delivery
The objective of this study is to compare scalpel vs. diathermy in abdominal wall incision in pregnant patients undergoing repeat elective cesarean delivery.
- Trial name
- NCT02493608
- Testing
- scalpel, Diathermy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Lower Esophageal Ring, Dysphagia
Trial of Electrosurgical Incision Versus Bougie Dilation of Symptomatic Lower Esophageal (Schatzki's) Rings
The primary objective of this study is to compare the efficacy of bougie dilation to electrosurgical incision of symptomatic schatzki's rings at one year follow-up in the presence of rabeprazole treatment.
- Trial name
- NCT00204750
- Testing
- Bougie Dilation, Needle-knife incision
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Surgical Site Infection, Anastomotic Leak
Oral Antibiotic Prophylaxis in Colorectal Surgery
The investigators perform a case-control study to compare preparation before elective colorectal surgery. The first group is a prospective patient - registry in all patients with mechanical bowel preparation (MBP) and oral…
- Trial name
- ABCR (NCT03759886)
- Testing
- Paromomycin Sulfate Powder
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Leipzig