Clinical trials: In Vitro Fertilization Outcome
IVF Outcome
Trigger Timing in Ovarian Stimulations
The use of antagonist ovulation stimulation program is increasing year by year, because of its convenience, flexibility, and prevention effect of ovarian hyperstimulation syndrome.
- Trial name
- NCT04163133
- Testing
- 1～2 days later trigger than regular timing
- Where
- China
- Volunteers
- 834 people
- Sponsor
- Peking University Third Hospital
Infertility
Ultrasound-guided Hydrosalpinx Aspiration During Egg Collection
· What we know: Hydrosalpinx and IVF About 40% of patients undergoing IVF have tubal disease and in 25%-30% of tubal disease patients there is fluid collection within the tube; hydrosalpinx.
- Trial name
- NCT00566956
- Testing
- Hydrosalpinx needle aspiration to arm 1
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Ongoing Pregnancy Rate, Vitamin D
The Effect of Vitamin D on in Vitro Fertilization Outcome
To date, several studies have been done to explore the relationship between Vitamin D level and IVF outcome; however, the results are controversial. Sample sizes in these studies mentioned above were relatively small.
- Conditions
- Ongoing Pregnancy Rate, Vitamin D, in Vitro Fertilization
- Trial name
- NCT02361827
- Testing
- Embryo transfer
- Where
- China
- Volunteers
- 688 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Depression, Anxiety
The Effect of Selective Serotonin Reuptake Inhibitor (SSRI) Treatment on Affective Symptoms and Fertility Treatment Outcome in Women Undergoing in Vitro Fertilization (IVF)
Women undergoing IVF show a high prevalence of depressive and anxiety symptoms. Furthermore, stress has harmful consequences on IVF and pregnancy outcomes. An immunological cascade was suggested to be involved in the process.
- Conditions
- Depression, Anxiety, In Vitro Fertilization
- Trial name
- NCT00989053
- Testing
- escitalopram
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
IVF
Ubiquinone vs. Ubiquinol Supplementation
The objective of this study is to determine if ubiquinol will result in improved reproductive outcomes in older women at a reduced oral dose compared to current standard treatment with ubiquinone.
- Trial name
- NCT06555575
- Testing
- Ubiquinone 200 Mg Oral Capsule, Ubiquinol 100 MG Oral Capsule
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Infertility, Endometriosis
The Influence of Adjuvant Medical Treatment of Peritoneal Endometriosis on the Outcome of IVF. A Prospective Randomized Analysis.
In this study of endometriosis patients we compare a common treatment of surgical therapy and medical treatment for 3 months (Zoladex) with patients receiving only surgical therapy.
- Trial name
- NCT01682642
- Testing
- Zoladex
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- AZ Jan Palfijn Gent
Aneuploidy, Pregnancy
The Effect of Co Enzyme Q10 Together With Fertility Drugs on Pregnancy Outcome of in Vitro Fertilization
The goal of our research is to increase live birth rates in infertile women and to reduce the incidence of aneuploidy leading to miscarriage and trisomies.
- Conditions
- Aneuploidy, Pregnancy, Miscarriage
- Trial name
- CoQ10-IVF (NCT01048385)
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Implantation Failure
Effect of Fire-Needle Combined With Regular Acupuncture on Pregnancy Outcome in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization
This study aims to evaluate whether fire-needle combined with regular acupuncture improves pregnancy outcomes in patients with recurrent implantation failure (RIF), compared to no or regular acupuncture.
- Trial name
- NCT07462754
- Testing
- no acupuncture, regular acupuncture, Fire needle combination group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Huazhong University of Science and Technology
Adenomyosis, Assisted Reproductive Technology
Low Molecular Weight Heparin on the Adenomyosis Patients'IVF-ET Outcome
In assisted reproductive technology, adenomyosis patients are characterized by lower clinical pregnancy rate, lower implantation rate and higher abortion rate.
- Trial name
- NCT04741295
- Testing
- Low molecular weight heparin
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Nanjing University
Infertility, Obesity
Weight Management Intervention for Obese Women and the Live Birth Outcome of in Vitro Fertilization (IVF)
The primary aim of the study is to evaluate if weight management intervention for obese women (BMI≥30<35 kg/m2) prior to IVF improves the outcome assessed as live birth per participating woman, as compared to women where no…
- Trial name
- NCT01566929
- Testing
- Low calorie diet treatment
- Where
- 9 sites in Denmark, Iceland and 1 more
- Volunteers
- 317 people
- Sponsor
- Sahlgrenska University Hospital
IVF Failure
Sildenafil Citrate of in Vitro Fertilization After Multiple IVF Failures Attributed to Poor Endometrial Development
The aim of this study is to evaluate the effect of sildenafil citrate on endometrial development in women with history of recurrent implantation failure after IVF
- Trial name
- NCT03044561
- Testing
- Sildenafil Citrate
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Female Infertility
There is a Value of Luteinizing Hormone Predictive of in Vitro Fertilization Treatment Outcome in Antagonist Protocols?
This study, prospective randomized controlled trial, tried to identify a cut off value of luteinizing hormone predictive of in vitro fertilization outcome in a fixed or flexible gonadotropin-releasing hormone antagonist…
- Trial name
- NCT02328924
- Testing
- LH value
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti
Hormone Disturbance
Oocyte Retrieval Progesterone Levels and IVF
Objective: To assess whether basal hormonal level can predict the elevation of P4 on the day of oocyte retrieval, as well as to examine the impact of P4 elevation on the day of oocyte retrieval on the outcome of assisted…
- Trial name
- NCT04447677
- Volunteers
- 164 people
- Sponsor
- University of Belgrade
In Vitro Fertilisation Outcome
Triple-arm pH Comparison
The culturing human embryo in vitro is a process of myriad contributing elements. From these factors is the pH of embryo culture media, which is crucial for embryo development.
- Trial name
- Tri-pH (NCT02896777)
- Testing
- Transfer embryo from pH 7.20±0.02 on either Day 3 or day 5/6, Transfer embryo from pH 7.3±0.02 either Day 3 or day 5/6, Transfer embryo from pH of 7.4±0.02 on either Day 3 or day 5/6
- Where
- 6 sites in Egypt
- Volunteers
- 2,273 people
- Sponsor
- Ibn Sina Hospital
Subfertility
BAP-EB as a Predictive Tool for Endometrial Receptivity and Pregnancy Outcome of IVF Treatment
To determine the predictive value of attachment rate of human embryonic stem cells (hESC)-derived trophoblast spheroids (BAP-EB, embryo surrogate) onto endometrial epithelial cells (EEC) on success of IVF treatment and to use the…
- Trial name
- NCT02713854
- Testing
- endometrial biopsy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Infertility
The Influence of Different Concentrations of Glucose in Culture Media on In Vitro Fertilization (IVF) Outcome of Sibling Oocytes
The importance of glucose in culture media on fertilization and embryo development is still controversial. Although it has been reported that glucose is essential for fertilization process and biosynthesis of membrane lipid and…
- Trial name
- NCT02066584
- Testing
- Sibling oocyte incubation
- Where
- Israel
- Volunteers
- 600 people
- Sponsor
- Hillel Yaffe Medical Center
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Infertility, Male
To Study the Effect of Magnetic Activated Sperm Sorting on the Outcome of in Vitro Fertilization-embryo Transplantation
Recent studies have evaluated the use of magnetic-activated sperm sorting (MASS) to reduce apoptotic spermatozoa and improve the outcome of infertile male with assisted reproductive technology (ART).
- Trial name
- MASS (NCT03968367)
- Testing
- Magnetic activated sperm sorting
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Li-jun Ding
Fertilization in Vitro
Influence of Heavy Metals Exposure on in Vitro Fertilization (IVF) Outcome
Exposure to heavy metals may interfere with basic cellular functions, including DNA synthesis. The aim of the study is to correlate heavy metals concentration in body fluids of reproductive importance and IVF outcome.
- Trial name
- NCT02971280
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Pregnancy
Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome
PIF: biomarker of pregnancy, miscarriage, premature birth, preeclampsia, placenta accreta. Except for serum hCG, no pregnancy-complication markers are widely employed to predict the need for medical intervention.
- Trial name
- PIFBlood1 (NCT01805102)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC