Clinical trials: In Vitro Fertilisation (IVF) Treatment
Infertility, Female
Time-lapse Monitoring of Early Embryo Development After Ovarian Stimulation During Infertility Treatment
The number of children conceived by assisted reproductive technology is increasing in Nordic countries as well as worldwide. An important factor of success in treatment of infertility is a short "time to pregnancy" with impact on…
- Trial name
- NCT01882166
- Testing
- fostimon, puregon
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Luteal Hormone Supplementation
A Phase III Study of FE 999913 in Japanese Female Patients Undergoing Fertility Treatment
The purposes of the study are to verify sufficient supplementation of luteal hormone after administrating FE999913 Vaginal Tablet twice a day (BID) or three times a day (TID) and to determine the efficacy and safety of FE999913…
- Trial name
- NCT01710514
- Testing
- FE 999913 vaginal tablet
- Where
- 6 sites in Japan
- Volunteers
- 108 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
Study to Estimate Seedchrony's Predictive Capacity in the Success of Embryo Implantation.
In Vitro Fertilization (IVF) success is below 40%, with Embryo Transfer the leading cause of IVF failure. This clinical investigation aims to evaluate if the levels of an intrauterine biomarker dissolved in the uterine fluid…
- Trial name
- Seedchrony02 (NCT06259084)
- Testing
- Seedchrony
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Manina Medtech
Endometriosis, Infertility
GnRH-a and Pregnancy Rate in In Vitro Fertilization (IVF) Cycles.
The investigators attempted to establish a rationale for the Gonadotropin Releasing Hormone-agonist (GnRH-a) administration, post-laparoscopically, in women with mild endometriosis (until stage II, according to AFS) who underwent…
- Trial name
- NCT01269125
- Testing
- Leuprolide, IVF
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- University of Ioannina
Thyroid Diseases
An Assessment of Aspirin Plus Prednisone Treatment for Euthyroid Women With Thyroid Autoimmunity
Thyroid autoimmunity(TAI) per se have adverse effect on pregnancy outcomes，and aspirin and prednisone were used frequently in antithyroid antibodies(ATA) positive infertile women in clinical practice, but the impact of these…
- Trial name
- NCT04943146
- Testing
- Prednisone 10 MG+aspirin 100MG
- Where
- 2 sites in China
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
IVF-ET, Hydrosalpinx
Comparing Radiological Tubal Blockage Versus Laparoscopic Salpingectomy in Infertile Women With Hydrosalpinx During in Vitro Fertilization Treatment
Hydrosalpinx (HX) has a detrimental effect on the rates of implantation, pregnancy, live delivery, and early pregnancy loss during in vitro fertilization (IVF).
- Trial name
- NCT03521128
- Testing
- radiological tubal blockage, laparoscopic salpingectomy
- Where
- China
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Fertility, In Vitro Fertilization
A Study Comparing a Shorter Exposure of Oocyte to Spermatozoa Versus a Standard Incubation on the Live Birth Rate of In-vitro Fertilization Treatment
In vitro fertilization (IVF) treatment is now commonly used to treat infertile couples. During IVF treatment, oocytes and sperm are routinely incubated overnight and this may lead to suboptimal culture conditions because of…
- Trial name
- NCT02534857
- Testing
- a shorter exposure of oocyte to spermatozoa
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Depression, Anxiety
The Effect of Selective Serotonin Reuptake Inhibitor (SSRI) Treatment on Affective Symptoms and Fertility Treatment Outcome in Women Undergoing in Vitro Fertilization (IVF)
Women undergoing IVF show a high prevalence of depressive and anxiety symptoms. Furthermore, stress has harmful consequences on IVF and pregnancy outcomes. An immunological cascade was suggested to be involved in the process.
- Conditions
- Depression, Anxiety, In Vitro Fertilization
- Trial name
- NCT00989053
- Testing
- escitalopram
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Female Infertility
Impact of Clomiphene Citrate Administration During the Early Luteal Phase on Endocrine Profile in IVF Cycles
The purpose of this study is to evaluate the effect on LH levels of the 5-day CC administration during luteal phase in oocyte donors, to investigate whether the CC corrects the suppressed LH levels in the luteal phase and whether…
- Trial name
- CLOFA (NCT01791751)
- Testing
- Clomifene Citrate
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
Infertility, Hypothalamic Amenorrhea
The Luveris In Vitro Fertilization Trial
The purpose of this study is to develop a new protocol using two different types of fertility drugs that is more similar to the way the hormones act in a normal menstrual cycle (period).
- Conditions
- Infertility, Hypothalamic Amenorrhea, Hyperprolactinemia
- Trial name
- NCT00889512
- Testing
- Luveris fixed dose, Luveris increasing dose
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University Reproductive Associates
Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Coasting is one of the means to reduce the risk of OHSS for patients at risk for severe OHSS. During coasting gonadotrophin administration is withheld until serum E2 levels drop to a range considered safe.
- Trial name
- NCT01109888
- Testing
- Cetrotide
- Sponsor
- Wolfson Medical Center
Diminished Ovarian Reserve (DOR)
Testing Herbal Pretreatment For IVF Success In Women With Low Ovarian Reserve
The goal of this clinical trial is to learn if a traditional Chinese herbal pretreatment can improve pregnancy outcomes in infertile women with diminished ovarian reserve (DOR) who are undergoing in vitro fertilization (IVF) or…
- Trial name
- PRIME (NCT07347340)
- Testing
- Bushen Tongzhi Formula
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Peking Union Medical College Hospital
Infertility, Endometriosis
The Influence of Adjuvant Medical Treatment of Peritoneal Endometriosis on the Outcome of IVF. A Prospective Randomized Analysis.
In this study of endometriosis patients we compare a common treatment of surgical therapy and medical treatment for 3 months (Zoladex) with patients receiving only surgical therapy.
- Trial name
- NCT01682642
- Testing
- Zoladex
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- AZ Jan Palfijn Gent
IVF Treatment
Self-operated Endo-vaginal Telemonitoring (SOET), an Economic and Patient-empowered Method for Ovarian Stimulation for In-vitro Fertilization (IVF)
The SOET project introduces a new strategy for routine follow-up of follicle growth during the hormonal treatment phase of an in-vitro fertilization (IVF) treatment cycle.
- Trial name
- SOET (NCT01781143)
- Testing
- Perform Echo at home.
- Where
- 4 sites in Belgium
- Volunteers
- 121 people
- Sponsor
- University Hospital, Ghent
Controlled Ovarian Stimulation, Infertility
Study to Examine Effect of Recombinant Luteinizing Hormone (r-Lh) and Recombinant Human Chorionic Gonadotropin (r-hCG) for Ovarian Stimulation in Assisted Reproduction Techniques (ART)
The study is a prospective, randomised, controlled, and non-blinded multi-center pilot study to evaluate endocrine efficacy of recombinant luteinizing hormone versus recombinant human chorionic gonadotropin administered during…
- Trial name
- NCT01339299
- Testing
- recombinant luteinizing hormone (r-LH), recombinant human chorionic gonadotropin (r-hCG)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Regionshospitalet Viborg, Skive
Infertility, Fertilization in Vitro
Low Molecular Weight Heparin in Recurrent Implantation Failure
Recurrent implantation failure is the failure to achieve a pregnancy after multiple attempts with in vitro fertilization treatment. The reason is usually obscure.
- Conditions
- Infertility, Fertilization in Vitro, Recurrent Implantation Failure
- Trial name
- NCT00750451
- Testing
- low molecular weight heparin (enoxaparine sodium), crinone 8% gel
- Where
- Turkey (Türkiye)
- Sponsor
- V.K.V. American Hospital, Istanbul
Cancer, Cancer in Pregnancy
ProspectiveFemaleAYA - Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes
In the past two decades, the evidence-based knowledge on the prevalence and risk factors for gonads impairment, including infertility, following cancer and numerous cancer treatment regimen has significantly increased.
- Conditions
- Cancer, Cancer in Pregnancy, Infertility, In Vitro Fertilisation (IVF) Treatment
- Trial name
- FemFertilAYA (NCT07622420)
- Volunteers
- 3,000 people
- Sponsor
- Karolinska Institutet
Infertility
Adjuvant Growth Therapy in in Vitro Fertilization
In an In Vitro Fertilization (IVF) cycle super ovulating drugs (gonadotropins) are usually taken to stimulate the ovaries to produce more than one egg.
- Trial name
- NCT01715324
- Testing
- Adjuvant Growth Hormon
- Where
- Canada
- Volunteers
- 288 people
- Sponsor
- Clinique Ovo
Female Infertility
There is a Value of Luteinizing Hormone Predictive of in Vitro Fertilization Treatment Outcome in Antagonist Protocols?
This study, prospective randomized controlled trial, tried to identify a cut off value of luteinizing hormone predictive of in vitro fertilization outcome in a fixed or flexible gonadotropin-releasing hormone antagonist…
- Trial name
- NCT02328924
- Testing
- LH value
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti
Infertility
Association of the Mediterranean Diet With Fertility Outcomes
Infertility affects one of every six couples and one out of ten couples may seek fertility treatment such as ovulation induction and assisted reproductive technologies. With respect to diet, several dietary factors, i.e.
- Trial name
- MedDietIVF (NCT03050944)
- Testing
- Lifestyle behaviour and dietary habits assessment
- Where
- Greece
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harokopio University