Clinical trials: Impulsivity
Drug-withdrawal., Drug Abuse
Clinical Studies on the Therapeutic Effects of Mirtazapine on Drug-craving in Cocaine Addicts.
INTRODUCTION. One of the main problems of the treatment of cocaine-dependent patients is the high rate of relapses occurs within the first months after detoxification.
- Conditions
- Drug-withdrawal., Drug Abuse, Drug-induced Depressive State, AOD Craving
- Trial name
- MADC (NCT01949571)
- Testing
- Mirtazapine (REMERON, Schering-Plough-Organon)
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Cocaine Dependence
Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse
This project proposes to investigate the role of brain connectivity in the mechanism of treatment response to dopaminergic medications in cocaine dependence.
- Trial name
- NCT02080819
- Testing
- levodopa/carbidopa 400/100 BID
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Behavior, Addictive, Cigarette Smoking
Practicing Self-Control Lowers the Risk of Smoking Lapse
The proposed study will investigate the role of self-control in smoking cessation and whether interventions that improve self-control can help reduce the risk of lapsing among smokers who wish to quit.
- Trial name
- NCT00349687
- Testing
- self-control practice
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University at Albany
Aggression, Hyperactivity
Infant Psychiatry Home Visitation Program
This is a proposed home visitation program for families of children with externalizing behaviors who are on the wait list for psychiatric assessment at BC Children's hospital.
- Conditions
- Aggression, Hyperactivity, Impulsive Behaviors
- Trial name
- NCT01483521
- Testing
- Clinical home visitation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Sexual Addiction
A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction
The study is intended to identify gene polymorphisms significantly associated with specific behavioral- and preoccupation-typologies of sexual addiction, and to identify additional potential genetic markers of sexual addiction.
- Trial name
- NCT02844985
- Testing
- No Intervention
- Where
- 8 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- American Foundation for Addiction Research
Substance Dependency, Addiction
Working Memory Training for Substance Dependent Individuals
Background: Substance abusers show impaired working memory (WM) functioning. Promising findings show training WM results in an improved working memory capacity (WMC) and a decrease of clinical symptoms in a range of disorders…
- Conditions
- Substance Dependency, Addiction, Anxiety, Depression
- Trial name
- NCT02119949
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Erasmus Medical Center
Impulsive Aggression Comorbid With ADHD in Children
Open-Label, Extension Study to 810P202
Open-label, extension study for subjects that completed 810P202 to examine long term safety and tolerability of repeated dosing of SPN-810M as an adjunctive therapy in children with Impulsive Aggression Comorbid with…
- Trial name
- NCT01416064
- Testing
- Molindone
- Where
- 28 sites in United States
- Volunteers
- 78 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Pathological Gambling
Dopamine Responsivity in Gamblers
This study deals with how people decide between rewards of different value. The investigators want to understand how the brain's dopamine system impacts this kind of decision making.
- Trial name
- NCT02772978
- Testing
- Tolcapone
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
HIV
Computer-Assisted HIV Prevention for Young Drug Users
In this study, the investigators are developing and evaluating an interactive, computer-assisted HIV, STD and disease prevention program for young substance abusers that incorporates effective components of both prevention…
- Trial name
- NCT00182585
- Testing
- computer-based HIV, STD & Hepatitis Education, educator-delivered HIV, STD and Hepatitis education
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- National Development and Research Institutes, Inc.
Substance Use Disorders, Eating Disorders
Substance Use and Eating Disorders : Food Craving and Addiction Transfer
Substance Use Disorder (SUD) and Eating Disorders (ED) are severe and persistent disturbances that are associated with significant harm.
- Trial name
- SUED (NCT05315635)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Hypersexuality, Compulsive Sexual Behavior
Effectiveness of ACT for Problematic Chemsex
Investigation of the efficacy of Acceptance and Commitment Therapy (ACT) for the psychological treatment of problematic chemsex.
- Conditions
- Hypersexuality, Compulsive Sexual Behavior, Sexualized Drug Use (Chemsex)
- Trial name
- ChemACT (NCT06406296)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Europea de Madrid
Alcoholism, Child Abuse, Sexual
Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse
This study will evaluate the effectiveness of trauma-focused group therapy for reducing HIV-risk behavior and revictimization among adult women survivors of childhood sexual abuse (CSA).
- Conditions
- Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior
- Trial name
- NCT00220597
- Testing
- Trauma-focused group therapy
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
Cortical Stimulation to Treat Obsessive Compulsive Disorder
The purpose of this study is to identify abnormal brain signals associated with Obsessive Compulsive Disorder (OCD) and psychiatric symptoms and to investigate novel therapeutic stimulation sites.
- Trial name
- NCT04958096
- Testing
- Standard Therapeutic Deep Brain Stimulation, Cortical Stimulation for PFC, Cortical Stimulation for ACC
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrew Moses Lee, MD, PhD
Social Networks, Addiction
Prevalence of Problematic Use of Social Media
In 2023, French individuals spend an average of two hours per day on social media platforms (SM), primarily Facebook, TikTok, X, YouTube, Instagram, and Snapchat.
- Trial name
- PURPLE (NCT06798480)
- Testing
- Self-administered survey
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Food Addiction
Food Addiction Clinical Treatment Program
The purpose of this current study is to establish the feasibility of, and preliminary support for, a clinical treatment program utilizing interventions from various empirically supported treatments for obesity-related eating…
- Trial name
- FACT (NCT04373343)
- Testing
- 16-week Food Addiction Clinical Treatment (FACT) Program
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Wake Forest University Health Sciences
Healthy
Functional Neuroimaging of Alcoholism Vulnerability (PIT)
This project compares Family History Positive (FHP) for alcoholism subjects to matched Family History Negative (FHN) subjects derived from the project Principal Investigator's National Institute on Alcohol Abuse and…
- Trial name
- CTNA (NCT01585168)
- Testing
- Memantine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Yale University
fMRI, Alcohol Drinking
Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers
Background: Ghrelin is a hormone in the human body that is mostly produced by the stomach. It makes people feel hungry, and also is connected with the desire to drink alcohol.
- Conditions
- fMRI, Alcohol Drinking, Alcoholism
- Trial name
- NCT01779024
- Testing
- Ghrelin, fMRI, Alcohol
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Opioid-use Disorder, Addiction
Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
The purpose of this study is to develop and then test an enhanced version of the parent study's collaborative care intervention for co-occurring disorders (CC-COD) to reduce the risk of suicide and overdose among individuals with…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder
- Trial name
- NCT04634279
- Testing
- Collaborative care Plus
- Where
- 12 sites in United States
- Volunteers
- 68 people
- Sponsor
- RAND
Tobacco Use Disorder
Modification of Goal-directed and Habitual Behavior in Addiction
This study aims to examine the modification of the hypothesized imbalance between goal-directed and habitual behavior and its neural correlates in smokers.
- Trial name
- NCT03764969
- Testing
- standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), Implicit computer-based habit-modifying training (ICHT)
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Internet Addiction Disorder
The Effect of the Nursing Intervention Program on Adolescent Problematic Internet Users
In this study; The effect of the nursing intervention program (education enriched with web 2.0 tools based on the Health Belief Model) on problematic internet use, loneliness and family harmony in adolescents who use the internet…
- Trial name
- NCT06302894
- Testing
- Self-sufficiency
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University