Clinical trials: Implementation Research
Acute Heart Failure (AHF), Implementation Research
Implementation of Acute Heart Failure Checklist
Patients with acute heart failure (AHF) commonly present to the emergency department (ED) with difficulty breathing and often have poor outcomes or death.
- Trial name
- NCT07727304
- Testing
- CAEP Acute Heart Failure (AHF) Best Practices Checklist Implementation, Usual care
- Where
- Canada
- Volunteers
- 5,040 people
- Sponsor
- Ottawa Hospital Research Institute
Implementation Research, Tobacco Cessation
Comparing Smartphone to In-person Training to Scale up a Tobacco Control Program for Teachers in India
This study aims to compare the implementation and effectiveness of the Tobacco-Free Teachers, Tobacco-Free Society (TFT-TFS) program when delivered through in-person training versus a smartphone-based training model.
- Trial name
- NCT05500235
- Testing
- Smart phone based training, In person training
- Where
- India
- Volunteers
- 2,718 people
- Sponsor
- Harvard School of Public Health (HSPH)
Implementation Research, Kidney Disease
Trial Without Borders IMPLEMENT-CKD: IMPLEMENTation of Evidence-Based SGLT2i to Reduce Global Burden of Cardiovascular and Chronic Kidney Disease
Chronic kidney disease (CKD) affects millions, especially in low- and middle-income countries, where many die early due to lack of treatment.
- Conditions
- Implementation Research, Kidney Disease, Cardiovascular Disease, Chronic Illness
- Trial name
- IMPLEMENT-CKD (NCT07854808)
- Testing
- Implementation of recommendations
- Where
- 3 sites in Fiji, Samoa and 1 more
- Volunteers
- 1,390 people
- Sponsor
- The University of Queensland
Nurse Practitioners, Implementation Research
Role Development, Implementation and Evaluation of Nurse Practitioners
Hospitals face new challenges in providing sustainable high quality care as the prevalence of chronic conditions, multimorbidity and the complexity of care increases.
- Conditions
- Nurse Practitioners, Implementation Research, Quality of Care
- Trial name
- NUPRA-DI (NCT05520203)
- Testing
- Care provided by the Nurse Practitioner
- Where
- 2 sites in Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Program Effectiveness, Program Implementation
Implementation Study With Embedded RCT of a Digital System of Parenting Support Within Government Services in South Africa
ParentText, a WhatsApp-based parenting support programme, is designed as a universal intervention to improve parent-child relationships (module 1) and promote child safety (module 2).
- Conditions
- Program Effectiveness, Program Implementation, Parent Child Relationship, Caregiver Child Relationship
- Trial name
- SWIFT (NCT07814261)
- Testing
- Module 1 - Improve My Relationship with My Teen/Child, Module 2 - Keep My Child/Teen Safe and Healthy
- Where
- South Africa
- Volunteers
- 4,961 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Nurse-Patient Relations, Implementation Research
Nurses in the Lead - Nursing Leadership and Autonomy in Function Focused Care in Hospital
The goal of this prospective before-after study (observational) is to implement Function Focused Care in Hospital (FFCiH), paying specific attention to the role of nurses and how they can take the leadership and autonomy in the…
- Conditions
- Nurse-Patient Relations, Implementation Research, Physical Inactivity, Physical Activities
- Trial name
- NCT06878820
- Testing
- Function Focused Care
- Where
- 3 sites in Netherlands
- Volunteers
- 425 people
- Sponsor
- Leiden University Medical Center
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Patient Monitoring, Wearable Devices
Continuous Vital Sign Monitoring in a Surgical Ward
Unsafe patient care remains a major contributor to global morbidity and mortality. In surgical wards, postoperative patients are typically monitored intermittently using the National Early Warning Score (NEWS-2), leaving periods…
- Conditions
- Patient Monitoring, Wearable Devices, Telemonitoring, Patient Safety
- Trial name
- NCT07690267
- Testing
- Continuous Vital Sign Monitoring (CVSM)
- Where
- Norway
- Volunteers
- 9,600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
TBI (Traumatic Brain Injury), Implementation Research
Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test
The objective of this study is to identify determinants for implementing the i-STAT Alinity whole blood traumatic brain injury (TBI) test for its Food and Drug Administration (FDA)-indicated use and to evaluate other potential…
- Trial name
- EDI (NCT07373509)
- Testing
- i-STAT Alinity TBI test
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Shawn Eagle
Team-effectiveness Research, School-based Interventions
Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD
The proposed project aims to integrate team-based implementation strategies with an established school-based intervention for children with ADHD, the Collaborative Life Skills Program (CLS), to enhance its implementation and…
- Conditions
- Team-effectiveness Research, School-based Interventions, Attention Deficit/ Hyperactivity Disorder, Implementation Science
- Trial name
- NCT06180681
- Testing
- Team-Enhanced Collaborative Life Skills Program, Standard Collaborative Life Skills Program
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
Implementation Research, Help Seeking
Teen Helpline Motivational Interviewing Study
The proposed study will establish a foundation for research within peer-delivered helplines for teens. It aims to evaluate the impact of a Motivational Interviewing training at peer-to-peer helpline.
- Trial name
- MI (NCT07639736)
- Testing
- Motivational Interviewing Training
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- San Diego State University
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Pain Management, Pain Assessment
Effectiveness and Implementation of a Clinical Pain Management Dashboard for the NICU
This study protocol describes a type 1 hybrid effectiveness-implementation study evaluating a clinical decision support dashboard for neonatal pain management in a tertiary NICU.
- Conditions
- Pain Management, Pain Assessment, Neonatal Intensive Care, Implementation Research
- Trial name
- NCT07629661
- Testing
- Implementation of clinical pain management dashboard
- Where
- Netherlands
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Frailty at Older Adults, Primary Care
Implementation of a Clinical Decision Support System in Primary Care for the Screening and Assessment of Frailty in Patients Aged 65 and Over
This observational study aims to evaluate the real-life use of a digital tool (Fragiclic) by general practitioners (GPs) and nurses to screen and assess frailty in adults aged 65 and over.
- Conditions
- Frailty at Older Adults, Primary Care, Geriatric Assessment, Implementation Research
- Trial name
- FRAGICLIC (NCT07570628)
- Where
- France
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- CNGE Conseil
Implementation Research, Artificial Intelligence (AI)
Barriers and Facilitators to Nursing Record With AI Technology Application
The goal of this study is to examine the facilitators and barriers to the comprehensive implementation of AI technology in nursing documentation.
- Conditions
- Implementation Research, Artificial Intelligence (AI), Nursing Documentation Burden
- Trial name
- NCT07532343
- Testing
- AI-based technologies systems to assist with nursing record
- Where
- Taiwan
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Surgery, Geriatric Assessment
Implementation Pilot of Preoperative CGA Before Major Surgery
The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery.
- Conditions
- Surgery, Geriatric Assessment, Health Services Research, Implementation Science
- Trial name
- NCT06184724
- Testing
- Implementation Package for CGA, Routine Clinical Care
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neonatal Resuscitation, Delivery Room Resuscitation
Supraglottic Airway for Resuscitation Trial
This is a hybrid type 3 effectiveness-implementation parallel cluster randomized superiority trial designed to compare two strategies to promote early supraglottic airway (SA) rescue during neonatal resuscitation, with a focus on…
- Conditions
- Neonatal Resuscitation, Delivery Room Resuscitation, Positive Pressure Ventilation, Infant, Newborn
- Trial name
- SUGAR (NCT07150923)
- Testing
- Enhanced Standard of Care ("Enhanced"), Enhanced Standard of Care ("Enhanced-Plus")
- Where
- 30 sites in United States
- Volunteers
- 36,503 people
- Sponsor
- Children's Hospital of Philadelphia
Intervention Effectiveness, Implementation Research
Charge Your Brainzzz: Evaluation of the Effectiveness and Implementation of an Integrated Approach to Improve Dutch Teenagers' Sleep Health
Poor sleep among teenagers is a major public health issue. Studies show that in the Netherlands, nearly half of adolescents don't wake up feeling rested, one in five feel sleepy during the day, one in four regularly wake up at…
- Trial name
- NCT07371637
- Testing
- Charge Your Brainzzz
- Where
- Netherlands
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Accidental Injuries, Global Child Health
The P-KIDs CARE Health Systems Intervention in Tanzania
The objective of the proposed research is to develop and pilot a locally-relevant, multicomponent intervention to streamline the triage process (e.g.
- Conditions
- Accidental Injuries, Global Child Health, Pediatric Emergency Medicine, Public Health System Research
- Trial name
- P-KIDs CARE (NCT06075108)
- Testing
- P-KIDs CARE
- Where
- Tanzania
- Volunteers
- 284 people
- Sponsor
- University of Utah
Healthy Lifestyle, Overweight
Deaf Weight Wise: Community-engaged Implementation Research to Promote Healthy Lifestyle Change With Deaf ASL Users
The purpose of the Deaf Weight Wise Implementation Study is to study with diverse partners the approaches and strategies that lead to successful implementation of Deaf Weight Wise (DWW), an evidence-based healthy lifestyle…
- Conditions
- Healthy Lifestyle, Overweight, Obesity, Cardiovascular Risks
- Trial name
- NCT05211596
- Testing
- Deaf Weight Wise intervention
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Rochester