Clinical trials: Implementation
Male Infertility Due to Azoospermia
Round Spermatid Injection Protocol
To evaluate embryology outcomes after application of a technique known as round spermatid injection (ROSI) into donor oocytes in a high-volume clinical infertility practice.
- Trial name
- ROSI (NCT04053309)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Cholelithiasis, Cholecystectomy, Laparoscopic
SAGES Safe Cholecystectomy Program in Polish Reality - Awareness, Implementation and Opinion on Usefulness
The study is designed to assess the awareness of the SAGES Safe Cholecystectomy Program among polish surgeons, as well as the degree of implementation of this Program during laparoscopic cholecystectomy performed in Poland.
- Trial name
- NCT03155321
- Testing
- It's an observational study - no intervention is planned
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Hypertension, Cardiovascular Diseases
Team-based Care to Improve Hypertension
The study is a stepped-wedge cluster randomized control trial to compare the effect of Practice Facilitation in 90 small-to-medium sized independent primary care practices on the adoption of team-based care.
- Trial name
- NCT05413252
- Testing
- Practice Facilitation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- New York University
Chronic Kidney Diseases
DDEP for Lifestyle Modification in Chronic Kidney Disease
This is a randomized controlled feasibility trial conducted on patients with Chronic Kidney Disease (CKD) and their significant other
- Trial name
- NCT06226649
- Testing
- Digital Dyadic Empowerment
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng Kung University
Global Developmental Delay
Design and Implementation of a Carer Aromatherapy Training (CAT) Program for Children With Global Developmental Delay in Hong Kong: A Mixed Qualitative Study Using the COM-B Framework
This project aims to design and implement a Carer Aromatherapy Training (CAT) program, guided by the Capability, Opportunity, Motivation and Behaviour (COM-B) model, to empower carers with safe and effective aromatherapy…
- Trial name
- CAT programme (NCT07800689)
- Testing
- Carer Aromatherapy Training (CAT) program and home massage with massage oil with the mixture of Petitgrain Mandarin (Citrus reticulate) essential oil and fractionated coconut oil
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Type2 Diabetes
eHealth Intervention on Physical Activity for Type 2 Diabetics - Frustrated by COVID-19
This pragmatic 3-arm randomized controlled trial is conducted within the primary health care setting. The trial evaluates the effectiveness of a personalized eHealth intervention based on a hip-worn accelerometer, smartphone…
- Trial name
- MySteps-CoV (NCT04587414)
- Testing
- eHealth +counselling contacts, eHealth, Usual care
- Where
- Finland
- Volunteers
- 122 people
- Sponsor
- UKK Institute
Gynecologic Surgery, General Anesthesia
Long-term Follow-up of Bio-signals and Quality of Recovery Following Implementation of ERAS Based on the Mobile Application
The goal of this clinical trial is to evaluate the effect of an Enhanced Recovery After Surgery (ERAS) protocol in patients undergoing gynecologic laparoscopic or robotic surgery under general anesthesia.
- Trial name
- NCT07868952
- Testing
- Enhanced Recovery After Surgery, Usual Care
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Wonju Severance Christian Hospital
Acute Myeloid Leukemia (AML)
Improving Delivery of Aging-Related Supportive Care for Older Adults With Acute Myeloid Leukemia
The goal of this clinical trial is to test a way of delivering supportive care to adults 60 years and older who are starting venetoclax-based treatment for newly diagnosed acute myeloid leukemia (AML).
- Trial name
- ACTIVE DEFAULT (NCT07777471)
- Testing
- Active Default
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Opioid-Related Disorders, Drug Overdose
Prescribe to Save Lives
The U.S. is in the midst of an epidemic of opioid overdose deaths. The common use of opioids among persons living with HIV, along with their common use of benzodiazepines, has resulted in high rates of opioid overdose among this…
- Trial name
- PTSL (NCT03175640)
- Testing
- Implementation intervention
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Baystate Medical Center
Delirium in the Intensive Care Unit
Nurse-Led Implementation of the ABCDEF Bundle
This study evaluated the effectiveness of a nurse-led implementation of the ABCDEF bundle, an evidence-based, interprofessional care framework, in the prevention and management of delirium among Intensive Care Unit (ICU)…
- Trial name
- NCT07054268
- Testing
- Nurse-Led ABCDEF Bundle Implementation
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Helwan University
Children with Medical Complexity, Child, Only
Emergency Care Action Plans for Infants with Medical Complexity
An Emergency Care Action Plan (ECAP) is a tool intended to be helpful to providers when treating a child with complex medical needs during an emergency.
- Conditions
- Children with Medical Complexity, Child, Only, Infant Morbidity, Infant Conditions
- Trial name
- ECAP (NCT06444282)
- Testing
- Emergency Care Action Plan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Vermont
Autism
"Opt-In" Early Intervention Program for Children Waiting to Receive an Autism Diagnosis
A growing body of literature documents the benefits of parent-mediated interventions for autism starting early in life . However, the median age of diagnosis in the US continues to be 49 months.
- Trial name
- NCT07081724
- Testing
- Online Parent Training in Early Behavioral Intervention (OPT-In-Early)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Drexel University
Depression
Major Depressive Disorder (MDD)
The purpose of this study is to assess the effectiveness of systematic screening for depression in high-risk patient participants in everyday clinical practice.
- Trial name
- NCT01662817
- Testing
- Intervention, Control
- Where
- Spain
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Post Traumatic Stress Disorder
A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSD
PTSD occurs in up to 17% of post-9/11 US Service Members and is associated with long-term functional impairment, family problems, unemployment, and suicidality.
- Trial name
- COOPERATE (NCT06990191)
- Testing
- Partnered Prolonged Exposure (PPE), Prolonged Exposure (PE)
- Where
- 4 sites in United States
- Volunteers
- 420 people
- Sponsor
- United States Department of Defense
Asthma in Children
Implementation of Asthma Community Home and School Management Program (Asthma CHAMPS)
The long-term goal is to implement an evidence-based asthma intervention based on the Center for Disease Control's recommended framework (EXHALE) within Baltimore City Public Schools (BCPS).
- Trial name
- NCT05814510
- Testing
- Asthma CHAMPS full program, Asthma CHAMPS Wait List Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Moderate Respiratory Distress, Severe Respiratory Distress
High Flow Nasal Oxygen Therapy an Implementation Study in Pediatric Wards
The purpose of this study is to prospectively evaluate the process of implementing HFNO in several MSF projects, varying according to geographical and programmatic contexts, population, health structures, human resources, and…
- Trial name
- HFNO (NCT06715423)
- Where
- Afghanistan
- Volunteers
- 960 people
- Sponsor
- Epicentre
Cancer, Chemotherapy-induced Peripheral Neuropathy
Clinician Decision Support Algorithm for Chemotherapy-Induced Peripheral Neuropathy
This research study is evaluating how well a decision support tool works to improve clinicians' use of recommended chemotherapy-induced peripheral neuropathy (CIPN) assessment and management strategies in participants receiving…
- Trial name
- NCT03514680
- Testing
- CIPN Assessment and Management Algorithm
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer
DeADT - Living Well With Prostate Cancer
The goal of this randomized de-implementation trial is to compare two strategies to reduce low-value androgen deprivation therapy (ADT) use for prostate cancer care.
- Trial name
- DeADT-LW (NCT06199986)
- Testing
- ADT Order Check Attestation (Or), Provider Script (Sc)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Functional Constipation (FC)
Implementation of Physical Therapy Protocol for Functional Constipation
The goal of this randomized controlled trial is to investigate the effects of standard medical treatment alone and the effects of adding different physiotherapy protocols to standard medical treatment on constipation severity…
- Trial name
- NCT07719504
- Testing
- Standard medical treatment, Maitland orthopedic manual therapy (MOMT), Russian current stimulation (ERS)
- Volunteers
- 60 people
- Sponsor
- Cairo University
Epilepsy, Status Epilepticus
Training Program to Improve EEG Competence
The goal of this clinical trial is to investigate the extent to which a practice-oriented training program for intensive care nursing staff and non-physician treatment teams can contribute to the earlier detection of epileptic…
- Conditions
- Epilepsy, Status Epilepticus, Status Epilepticus, Electrographic, Status Epilepticus, Non-Convulsive
- Trial name
- EPI-Train (NCT07689084)
- Testing
- Training Program
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital Marburg