EpilepsyEPI-TrainNCT07689084
Training Program to Improve EEG Competence
A study testing Training Program in people with Epilepsy and Status Epilepticus, run by University Hospital Marburg at 1 site in Germany.
Trial summary
The goal of this clinical trial is to investigate the extent to which a practice-oriented training program for intensive care nursing staff and non-physician treatment teams can contribute to the earlier detection of epileptic seizures, with particular emphasis on SE. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Epilepsy, Status Epilepticus, Status Epilepticus, Electrographic
- What is being tested?
- Training Program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 18 participants
- Where
- 1 siteGermany
- Study dates
- 4 Nov 2025to 31 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- neurocritical care nursing staff and non-physician treatment teams at the Neurocritical Care Units of Marburg University Hospital
Who cannot join
- under 18 years old
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Implementation of a Training Program to Improve EEG Competence in Neurocritical Care Nursing and Non-Physician Treatment Teams for the Recognition of Epileptiform and Ictal Patterns (EPI-TRAIN: EEG Training for the Detection of Pathological Ictal Patterns in Neurocritical Care)
The goal of this clinical trial is to investigate the extent to which a practice-oriented training program for intensive care nursing staff and non-physician treatment teams can contribute to the earlier detection of epileptic seizures, with particular emphasis on SE.
Further objectives include enhancing competence in EEG interpretation and minimizing existing communication and procedural barriers within the interdisciplinary treatment team.
Read more
Participants will participate in a half-day training session, which will include:
- attending a specialist lecture,
- completing two knowledge assessments and one evaluation questionnaire,
- completing an additional brief evaluation questionnaire after one month, and
- completing a further brief evaluation questionnaire after three months to assess the sustainability of the learning outcomes.
- Conditions
- Epilepsy, Status Epilepticus, Status Epilepticus, Electrographic, Status Epilepticus, Non-Convulsive, Healthy, Training Study
- Being tested
- Training Program
- Keywords
- Training Program
- Medical subject headings
- Epilepsy, Status Epilepticus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Training ProgramOther
1x Training Program for the neurocritical care nursing staff and non-physician treatment teams at the Neurocritical Care Units
| Study group | Role | What they receive |
|---|---|---|
| Training Group | Experimental | Not described Receives: Other: Training Program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of correct responses on the study-specific 16-item EEG Knowledge Questionnaire
Number of correctly answered items (range 0-16) on a study-specific 16-item multiple-choice questionnaire assessing EEG knowledge and seizure recognition.
Measured: Baseline (before the training session) and immediately after completion of the training session (Day 0).
Secondary outcomes (1)
Responses to items of a study-specific EEG training evaluation questionnaire (6-point Likert scale)
Responses to individual questionnaire items evaluating participants' perceptions of the training program and EEG use in clinical practice. Individual item scores (1 = strongly agree to 6 = strongly disagree) will be reported separately.
Measured: Immediately after completion of the training session (Day 0), approximately 1 month (30 ± 7 days), and approximately 3 months (90 ± 14 days) after completion of the training session.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jul 2026
- Study start4 Nov 2025
- Primary completion27 Jan 2026
- Study completion31 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for EpilepsyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Structured training program for the neurocritical care nursing staff and non-physician treatment teams at the Neurocritical Care Units
- Masking
- None (open label)
- Enrolment
- 18 participants (actual)
Sponsor and investigators
- Lead sponsor
- University Hospital Marburg
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Leona Möller, University Hospital Marburg
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07689084
- Sponsor's protocol ID
- 25-170 BO
- Acronym
- EPI-Train
- Status last verified
- Jul 2026
- First submitted
- 8 Jun 2026
- Last updated
- 8 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: * Two knowledge assessments and one evaluation questionnaire directly after the training program * Additional brief evaluation questionnaire after one month and after three months
Publications
Thijs RD, Surges R, O'Brien TJ, Sander JW. Epilepsy in adults. Lancet. 2019 Feb 16;393(10172):689-701. doi: 10.1016/S0140-6736(18)32596-0. Epub 2019 Jan 24.
PubMed 30686584Leitinger M, Trinka E, Giovannini G, Zimmermann G, Florea C, Rohracher A, Kalss G, Neuray C, Kreidenhuber R, Hofler J, Kuchukhidze G, Granbichler C, Dobesberger J, Novak HF, Pilz G, Meletti S, Siebert U. Epidemiology of status epilepticus in adults: A population-based study on incidence, causes, and outcomes. Epilepsia. 2019 Jan;60(1):53-62. doi: 10.1111/epi.14607. Epub 2018 Nov 26.
PubMed 30478910Kaleem S, Kang JH, Sahgal A, Hernandez CE, Sinha SR, Swisher CB. Electrographic Seizure Detection by Neuroscience Intensive Care Unit Nurses via Bedside Real-Time Quantitative EEG. Neurol Clin Pract. 2021 Oct;11(5):420-428. doi: 10.1212/CPJ.0000000000001107.
PubMed 34840869Goswami I, Bello-Espinosa L, Buchhalter J, Amin H, Howlett A, Esser M, Thomas S, Metcalfe C, Lind J, Oliver N, Kozlik S, Mohammad K. Introduction of Continuous Video EEG Monitoring into 2 Different NICU Models by Training Neonatal Nurses. Adv Neonatal Care. 2018 Aug;18(4):250-259. doi: 10.1097/ANC.0000000000000523.
PubMed 29889725Falco-Walter J. Epilepsy-Definition, Classification, Pathophysiology, and Epidemiology. Semin Neurol. 2020 Dec;40(6):617-623. doi: 10.1055/s-0040-1718719. Epub 2020 Nov 5.
PubMed 33155183
Study at a glance
From the registry record, last updated by the sponsor on 8 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Implementation of a Training Program to Improve EEG Competence in Neurocritical Care Nursing and Non-Physician Treatment Teams for the Recognition of Epileptiform and Ictal Patterns (EPI-TRAIN: EEG Training for the Detection of Pathological Ictal Patterns in Neurocritical Care)
- ClinicalTrials.gov ID
- NCT07689084
- Acronym / sponsor ID
- EPI-Train / 25-170 BO
- Conditions
- Epilepsy, Status Epilepticus, Status Epilepticus, Electrographic, Status Epilepticus, Non-Convulsive, Healthy, Training Study
- Keywords
- Training Program
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 18 participants (actual)
- Lead sponsor
- University Hospital MarburgUniversity, hospital or other
- Study start
- 4 Nov 2025 (actual)
- Primary completion
- 27 Jan 2026 (actual)
- Study completion
- 31 May 2026 (actual)
- First posted
- 8 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to investigate the extent to which a practice-oriented training program for intensive care nursing staff and non-physician treatment teams can contribute to the earlier detection of epileptic seizures, with particular emphasis on SE.
Further objectives include enhancing competence in EEG interpretation and minimizing existing communication and procedural barriers within the interdisciplinary treatment team.
Participants will participate in a half-day training session, which will include:
- attending a specialist lecture,
- completing two knowledge assessments and one evaluation questionnaire,
- completing an additional brief evaluation questionnaire after one month, and
- completing a further brief evaluation questionnaire after three months to assess the sustainability of the learning outcomes.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Structured training program for the neurocritical care nursing staff and non-physician treatment teams at the Neurocritical Care Units
| Arm | Type | Receives |
|---|---|---|
| Training Group | Experimental | Other: Training Program |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- neurocritical care nursing staff and non-physician treatment teams at the Neurocritical Care Units of Marburg University Hospital
Key exclusion criteria (1 listed)
- under 18 years old
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Training Program1x Training Program for the neurocritical care nursing staff and non-physician treatment teams at the Neurocritical Care Units | Other | Training Group |
Primary outcome
Number of correct responses on the study-specific 16-item EEG Knowledge Questionnaire
Time frame: Baseline (before the training session) and immediately after completion of the training session (Day 0).
Number of correctly answered items (range 0-16) on a study-specific 16-item multiple-choice questionnaire assessing EEG knowledge and seizure recognition.
1 secondary outcome
Responses to items of a study-specific EEG training evaluation questionnaire (6-point Likert scale)
Time frame: Immediately after completion of the training session (Day 0), approximately 1 month (30 ± 7 days), and approximately 3 months (90 ± 14 days) after completion of the training session.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jul 2026.
- Background: PubMed 30686584Thijs RD, Surges R, O'Brien TJ, Sander JW. Epilepsy in adults. Lancet. 2019 Feb 16;393(10172):689-701. doi: 10.1016/S0140-6736(18)32596-0. Epub 2019 Jan 24.
- Background: PubMed 30478910Leitinger M, Trinka E, Giovannini G, Zimmermann G, Florea C, Rohracher A, Kalss G, Neuray C, Kreidenhuber R, Hofler J, Kuchukhidze G, Granbichler C, Dobesberger J, Novak HF, Pilz G, Meletti S, Siebert U. Epidemiology of status epilepticus in adults: A population-based study on incidence, causes, and outcomes. Epilepsia. 2019 Jan;60(1):53-62. doi: 10.1111/epi.14607. Epub 2018 Nov 26.
- Background: PubMed 34840869Kaleem S, Kang JH, Sahgal A, Hernandez CE, Sinha SR, Swisher CB. Electrographic Seizure Detection by Neuroscience Intensive Care Unit Nurses via Bedside Real-Time Quantitative EEG. Neurol Clin Pract. 2021 Oct;11(5):420-428. doi: 10.1212/CPJ.0000000000001107.
- Background: PubMed 29889725Goswami I, Bello-Espinosa L, Buchhalter J, Amin H, Howlett A, Esser M, Thomas S, Metcalfe C, Lind J, Oliver N, Kozlik S, Mohammad K. Introduction of Continuous Video EEG Monitoring into 2 Different NICU Models by Training Neonatal Nurses. Adv Neonatal Care. 2018 Aug;18(4):250-259. doi: 10.1097/ANC.0000000000000523.
- Background: PubMed 33155183Falco-Walter J. Epilepsy-Definition, Classification, Pathophysiology, and Epidemiology. Semin Neurol. 2020 Dec;40(6):617-623. doi: 10.1055/s-0040-1718719. Epub 2020 Nov 5.
- Individual participant dataSharing planned: Yes. * Two knowledge assessments and one evaluation questionnaire directly after the training program * Additional brief evaluation questionnaire after one month and after three months
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Training Program in people with Epilepsy and Status Epilepticus, run by University Hospital Marburg at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of correct responses on the study-specific 16-item EEG Knowledge Questionnaire (time frame: Baseline (before the training session) and immediately after completion of the training session (Day 0).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07689084, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jul 2026.