Clinical trials: Immunization Programs
Kaposiform Hemangioendothelioma
The Effect of Sirolimus on Immunizations During the Treatment of Kaposiform Hemangioendothelioma
To research and explore the antibody protection and immune memory after vaccination in children with KHE during sirolimus administration.
- Trial name
- NCT05351216
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Bordetella Pertussis, Whooping Cough
Pertussis Immunization Programs in Low Income Countries - Ivory Coast
Due to waning of infectious as well as vaccine immunity and lack of vaccination boosters, a large number of adolescents and adults are no longer immunized against Bordetella pertussis, the agent of whooping cough and consequently…
- Trial name
- PERILIC-IC (NCT03388034)
- Testing
- Nasopharyngeal sampling, Blood Sampling
- Where
- 5 sites in Côte d’Ivoire
- Volunteers
- 789 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Human Papilloma Virus, HPV-Related Carcinoma
A Tailored, Health Communication Intervention for HPV Vaccine Hesitant Families
The human papillomavirus (HPV) causes 90% of cervical cancers and is implicated in multiple other cancers. The HPV vaccine can prevent the vast majority of these cancers, but it is underused in adolescents, especially among those…
- Conditions
- Human Papilloma Virus, HPV-Related Carcinoma, Vaccine Refusal, Parents
- Trial name
- NCT04380623
- Testing
- Mobile Phone-Based Web-Page: HPV vaccine
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Human Papilloma Virus, Cervical Cancer
Promise Women Project
The goal of this study is to develop and test an intervention program to improve cervical cancer prevention among Muslim American women.
- Trial name
- NCT05862844
- Testing
- Promise women project (Promote Cervical Cancer Prevention Methods Among Muslim Women in Virginia )
- Where
- 4 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mark Dignan, PhD
Vaccine Hesitancy, Health Education
Effect of Primary Care Education on Parents' Health-Related Perceptions and Attitudes
This study aims to evaluate the effect of a structured education program delivered in primary health care settings on parents of children aged 0-2 years.
- Conditions
- Vaccine Hesitancy, Health Education, Digital Health Literacy, Eco-anxiety
- Trial name
- NCT07381088
- Testing
- Structured Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Rabies
Rabies Immune Plasma Booster Study
Rabies immune globulin is a product that is lifesaving to unvaccinated individuals exposed to the rabies virus. Rabies immune globulin is made from plasma from immune donors.
- Trial name
- NCT01063140
- Testing
- Rabies Vaccine (RabAvert), Rabies Vaccine (Imovax)
- Where
- 10 sites in United States
- Volunteers
- 491 people, healthy volunteers welcome
- Sponsor
- CSL Behring
Integrated Care, Adolescent
Integrated HPV Vaccination and Adolescent Health in Tanzania
Background: Cervical cancer is a serious global public health problem, particularly in sub-Saharan Africa, where it is the leading cause of cancer in women, with around 70,722 new cases each year.
- Conditions
- Integrated Care, Adolescent, HPV
- Trial name
- SHARP-TZ (NCT06915844)
- Testing
- SHARP Tanzania
- Where
- Tanzania
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Cervical Carcinoma, Human Papillomavirus-Related Malignant Neoplasm
I Vaccinate: Testing Multi-Level Interventions to Improve HPV Vaccination
This trial studies how well a multi-level health system-based intervention works in improving human papillomavirus (HPV) vaccine initiation and completion among children in health systems in four Appalachian states.
- Trial name
- IVaccinate (NCT04452526)
- Testing
- Best Practice, Educational Intervention, Questionnaire Administration
- Where
- 4 sites in United States
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Adherence to Vaccination Schedules, Timeliness of Vaccination
SMS Mobile Technology to Improve Early Childhood Vaccine Coverage in Guatemala
This project plans to learn more about whether sending text messages to parents on their mobile phones to remind them when their child is due for his or her next vaccination will improve children getting vaccinated on time.
- Conditions
- Adherence to Vaccination Schedules, Timeliness of Vaccination, Acceptability of SMS Reminder Program
- Trial name
- SMSVaxGuate (NCT02567006)
- Testing
- SMS message, Usual care
- Where
- 2 sites in Guatemala
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Child Mortality
Improving Care Through Azithromycin Research for Infants in Africa
Infectious diseases are among the most common causes of mortality in the over 2.5 million children under 5 years of age (U5) who died in 2018 in sub-Saharan Africa (SSA).
- Trial name
- ICARIA (NCT04235816)
- Testing
- Azithromycin
- Where
- Sierra Leone
- Volunteers
- 20,560 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Influenza Vaccines, Influenza, Human
Financing Strategies of Influenza Vaccination in China
This trial focuses on influenza vaccination among three recommended groups in China. Data concerning the economic burden of influenza-like illness (ILI), vaccine hesitancy, discrete choice experiment, immunization records and…
- Conditions
- Influenza Vaccines, Influenza, Human, Cost of Illness, Health Knowledge, Attitudes, Practice
- Trial name
- NCT04038333
- Testing
- No intervention
- Where
- 3 sites in China
- Volunteers
- 13,542 people, healthy volunteers welcome
- Sponsor
- Peking University
Tuberculosis, Diphtheria
Evaluation of an Infant Immunization Encouragement Program in Nigeria
Previous studies have shown that a small incentive can have a large impact on health behaviors like vaccinating children. New Incentives, an international non-governmental organization (NGO), aims to boost demand for immunization…
- Conditions
- Tuberculosis, Diphtheria, Tetanus, Pertussis
- Trial name
- NCT03870061
- Testing
- All Babies Are Equal Initiative (conditional cash transfer program)
- Where
- 3 sites in Nigeria
- Volunteers
- 5,187 people, healthy volunteers welcome
- Sponsor
- GiveWell
Cervical Cancer, Breast Cancer
Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 1
The purpose is to evaluate implementation of a community-based prevention project aimed at increasing early detection and prevention of breast and cervical cancer through education and navigation and to increase breast and…
- Trial name
- SEMM1 (NCT06082505)
- Testing
- Education, Navigation to clinic
- Where
- United States
- Volunteers
- 8,262 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hepatitis B
Neovac 2 Burkina Faso: Impact of the Integration of Hepatitis B Birth Dose Vaccine Into the Infant Immunization Schedule
Hepatitis B virus (HBV) infection is an important global health problem, and the WHO adopted a strategy to eliminate HBV infection as a public health threat by the year 2030.
- Trial name
- NEOVAC2BK (NCT04029454)
- Testing
- birth dose vaccination against hepatitis B strategy
- Where
- 2 sites in Burkina Faso
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Healthy
Safety and Efficacy of Two Tetanus-Diphtheria Vaccines for a Donor Hyper Immunization Program
Many plasma donation centers have Tetanus immunization programs that are implemented in order to collect plasma with high levels of tetanus antibodies.
- Trial name
- NCT02673255
- Testing
- Tetanus and Diphtheria (Td) Vaccine
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Biomat USA, Inc.
Tetanus, Diphtheria and Acellular Pertussis Vaccination
Safety and Immunogenicity Study of Tdap Vaccinations for Plasma Donors
The goal of this clinical trial is to investigate the safety and tetanus antibody response to a Tdap vaccine in healthy plasma donors.
- Trial name
- NCT05662852
- Testing
- Tdap
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- ABO Holdings, Inc.
Bordetella Pertussis, Whooping Cough
Pertussis Immunization Programs in Low Income Countries
Due to waning of infectious as well as vaccine immunity and lack of vaccination boosters, a large number of adolescents and adults are no longer immunized against Bordetella pertussis, the agent of whooping cough and consequently…
- Trial name
- PERILIC (NCT02983487)
- Testing
- Nasopharyngeal sampling, Blood Sampling
- Where
- 3 sites in Cambodia, Madagascar and 1 more
- Volunteers
- 3,587 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Pneumococcal Infections
Study Evaluating Streptococcus Pneumoniae Nasopharyngeal Carriage Rate in Children Receiving Prevnar®
Primary Objective: To evaluate the impact of PCV7 vaccination on NP carriage rate of vaccine serotypes and serotype distribution Secondary Objective: To evaluate the impact of PCV7 vaccination on NP carriage of antibiotic…
- Trial name
- NCT00488371
- Testing
- Pneumococcal Conjugated Vaccine (Prevnar®)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Gastrointestinal Diseases
Evaluation of Universal Rotavirus Vaccination Program
Two rotavirus vaccines have been authorized for use in Canada: RotaTeq®, Merck Frost Canada, Inc. and Rotarix®, Glaxo Smith Kline (GSK).
- Trial name
- NCT01273077
- Where
- Canada
- Volunteers
- 12,705 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Not Condition-specific
Promoting Flu Vaccination Through a Mobile Wellness Program
The investigators design a 6-week messaging campaign aimed at promoting flu vaccination among fully insured members of a national payer that participate in a wellness program offered by the insurer through a mobile app.
- Trial name
- NCT02908893
- Testing
- In-app and push notification mobile messages
- Where
- United States
- Volunteers
- 50,286 people, healthy volunteers welcome
- Sponsor
- Evidation Health