Clinical trials: Imaging
Gastrointestinal Stromal Tumors, Gastric Subepithelial Tumors
Development of a Multimodal AI System for GIST Management
Background: Gastrointestinal Stromal Tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Accurate pre-operative diagnosis, risk stratification, and genotyping are critical for determining the…
- Conditions
- Gastrointestinal Stromal Tumors, Gastric Subepithelial Tumors, Gastric Leiomyoma, Artificial Intelligence (AI)
- Trial name
- NCT07454967
- Testing
- Multimodal AI Analysis System
- Where
- 9 sites in China
- Volunteers
- 300 people
- Sponsor
- Qun Zhao
Dental Plaque Accumulation, Oral Hygiene, Oral Health
3D Volumetric Plaque Assessment on Teeth, Composite Restorations, and Ceramic Veneers Using an Intraoral Scanner
The goal of this observational study is to evaluate and compare a 3D intraoral scanner-based, computer-assisted approach for assessing dental biofilm/plaque accumulation on natural teeth and restorative surfaces with a…
- Conditions
- Dental Plaque Accumulation, Oral Hygiene, Oral Health, Dental Materials, Dental Plaque Imaging Methods
- Trial name
- NCT07421687
- Testing
- Intraoral scanning (TRIOS 3) with plaque disclosure assessment, Conventional plaque scoring (TMQHPI) after plaque disclosure
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Trakya University
Imaging
Evaluation of C-arm PCD-CBCT for Image-Guided Interventions
The overarching objective of the project is to develop a new C-arm interventional x-ray imaging platform that integrates both a photon counting detector and a flat panel detector to provide high image quality and quantitative…
- Trial name
- NCT07092553
- Testing
- C-arm PCD-CBCT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Healthy Adult, Athlete
Comparison Between Eccentric Hamstring Training and Sprint-Specific Training
The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a…
- Conditions
- Healthy Adult, Athlete, Exercise Training, Sport
- Trial name
- NCT07716319
- Testing
- RDL, NHE, Sprint testing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cardiac Resynchronization Therapy, Magnetic Resonance Imaging (MRI)
MRI Assessment of Patient Suitability for Cardiac Resynchronization Therapy (CRT)
The goals of this project are to: 1) explore the potential use of magnetic resonance imaging (MRI) data for improved prediction of response to cardiac resynchronization (CRT), and 2) use the MRI-derived data together with a…
- Trial name
- NCT02728336
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Transcranial Direct Current Stimulation, Post-Concussion Syndrome
Effects of tDCS for Enhancing Cognitive Function in Individuals With Persistent Post-Concussion Syndrome
Globally, 10 million new traumatic brain injury (TBI) cases are estimated annually, with mild traumatic brain injury (mTBI) accounting for 75-90% of all TBI cases.
- Conditions
- Transcranial Direct Current Stimulation, Post-Concussion Syndrome, Functional Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy
- Trial name
- NCT06376500
- Testing
- tDCS with cognitive training programme
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Mild Stroke, Acute Ischemic Stroke
Endovascular Treatment for Mild Stroke With Acute Anterior Circulation Large Vessel Occlusion
Exploring the Efficacy and Safety of Emergent Endovascular Treatment in Patients with Mild Ischemic Stroke Caused by Acute Anterior Circulation Large Vessel Occlusion based on Perfusion Imaging Screening
- Conditions
- Mild Stroke, Acute Ischemic Stroke, Endovascular Treatment, Perfusion Imaging
- Trial name
- NCT06179017
- Testing
- Experimental group:Intervention Group, Control group:best medical treatment
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhangzhou Municipal Hospital
Guided Bone Regeneration, Bone Resorption
The Effect of IPD on Lateral Bone Augmentation
Guided Bone Regeneration (GBR) is a widely used technique during dental implant surgery to help rebuild bone around the implant and improve its long-term appearance and stability.
- Conditions
- Guided Bone Regeneration, Bone Resorption, Diagnostic Imaging
- Trial name
- NCT06999915
- Testing
- Group 1 (Test Group): IP and GBR as an over-contour augmentation beyond IPD, Group 2 (Control Group): IP and GBR as a contour augmentation up to IPD
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Queen Mary University of London
Cardiovascular Disease, Cardiac Magnetic Resonance Imaging
Association Between 4D MRI Parameters and the Clinical Characteristics and Prognosis of Major Chronic Diseases
Cancer and cardiovascular diseases are among the leading causes of morbidity and mortality worldwide. Advanced imaging techniques such as 4D magnetic resonance imaging (MRI) enable quantitative assessment of hemodynamic and…
- Conditions
- Cardiovascular Disease, Cardiac Magnetic Resonance Imaging, Neoplasm
- Trial name
- 4D-MRI (NCT07678606)
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ulsan University Hospital
Healthy Volunteers, Imaging Evaluation
Multimodal Cardiovascular and Hepatic Population Imaging
Medical imaging is increasingly important for understanding diseases, detecting them early, and personalizing treatments. New imaging techniques, which can measure processes in the body without surgery, are opening the door to a…
- Trial name
- ICONIC (NCT06906042)
- Testing
- Imaging examinations, Paramedical examinations, Medical examination
- Where
- France
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pilot Study, PET/CT Imaging
A Pilot Study to Correlate 4-18F- Fluoro-1-naphthol 18F-4FN PET/CT Imaging With Graft Versus Host Disease Manifestations
To study the safety and possible side effects of using the imaging agent 4-[18F]Fluoro-1-Naphthol (also called [18F]4FN) in PET/CT scans for participants with chronic GVHD.
- Conditions
- Pilot Study, PET/CT Imaging, Host Disease Manifestation
- Trial name
- NCT07325253
- Testing
- [18F]-4FN, PET-CT
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- M.D. Anderson Cancer Center
Localized Prostate Cancer, Positive Surgical Margin
SPECTRA: Intraoperative Hyperspectral Imaging for Prostate Cancer
Radical prostatectomy (RP) is currently one of the gold standard of care in managing localized prostate cancer (Pca). However, despite advances in Robot-Assisted RP (RARP), cancer cells may still be found (up to 42%) at the edge…
- Conditions
- Localized Prostate Cancer, Positive Surgical Margin, Hyperspectral Imaging
- Trial name
- SPECTRA (NCT07826858)
- Testing
- HyperSpectral imaging acquisition of ex-vivo prostate specimen prior formalin fixation (fresh acquisition)..
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Massimo Valerio
Whole Body Imaging, Prostate
AI Technologies for Enhanced and Celerated High-Field WB-MRI
Single-center, cross-sectional observational study assessing the feasibility of advanced accelerated MRI sequences versus standard ones in terms of image quality, diagnostic reliability, and acquisition time.
- Conditions
- Whole Body Imaging, Prostate, MRI, Lung
- Trial name
- AITECH-MRI (NCT07678320)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Binge Eating Behaviour, Eating Disorders
Biobehavioral Mechanisms of Activity and Loss of Control Eating in Children
Loss of control eating in children and adolescents is associated with a host of negative physical and psychological health outcomes and a prognostic marker for development of eating disorders.
- Conditions
- Binge Eating Behaviour, Eating Disorders, Physical Activity, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT07823153
- Testing
- Go/No-go task, Visual food task, Emotion regulation task
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Magnetic Resonance Imaging, Cerebrovascular Circulation
Brain Blood Vessel Responses to Changes in Blood Flow
Brain blood flow will be measured during a simulated postural change test and while breathing increased levels of carbon dioxide using magnetic resonance imaging.
- Trial name
- NCT06629077
- Testing
- MRI, Prazosin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Antenatal Care, Maternal Health
AI Blind-Sweep Ultrasound for Antenatal Screening by Non-Specialist Health Workers in Rural DR Congo
FS2 evaluates the diagnostic accuracy and implementation feasibility of an AI-assisted blind-sweep obstetric ultrasound (SPAQ E-con AI), operated by trained non-specialist health workers, for antenatal screening in rural…
- Conditions
- Antenatal Care, Maternal Health, Gestational Age, Placenta Praevia
- Trial name
- FS2 (NCT07677670)
- Testing
- SPAQ E-con AI blind-sweep ultrasound
- Where
- Democratic Republic of the Congo
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- SOIK Corporation Sarl
Olfactory Dysfunction, Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Neural Dissimilarity in Patients With Chronic Rhinosinusitis With Nasal Polyps Treated With Biologics
This project will focus on rehabilitation of olfactory dysfunction in patients with chronic rhinosinusitis with polyps given biological treatment based on functional magnetic resonance imaging.
- Conditions
- Olfactory Dysfunction, Chronic Rhinosinusitis With Nasal Polyps (CRSwNP), Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT07819162
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stroke, Intracranial Atherosclerosis
High-resolution Magnetic Resonance Imaging of Intracranial Atherosclerotic Plaques in Ischemic Stroke
Intracranial atherosclerotic disease is the most common cause of ischemic stroke in Asia, also in China. Currently, despite vascular recanalization therapy, statins are one of the main drug choices for treating atherosclerotic…
- Conditions
- Stroke, Intracranial Atherosclerosis, High Resolution Magnetic Resonance Imaging
- Trial name
- NCT05897645
- Testing
- Registration
- Where
- China
- Volunteers
- 2,110 people
- Sponsor
- General Hospital of Shenyang Military Region
Dental Plaque (Diagnosis), Dental Plaque Imaging Methods
Digital Quantification of Dental Plaque Based on Intraoral Scanner Images
This diagnostic validation study aims to develop and validate a digital method for dental biofilm quantification using three-dimensional images obtained by an intraoral scanner.
- Conditions
- Dental Plaque (Diagnosis), Dental Plaque Imaging Methods, Dental Plaque, Gingivitis
- Trial name
- NCT07152314
- Testing
- Digital plaque quantification using intraoral scanner
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Breathing, Lung Function Decreased
Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function
This study will examine the relationship of airways resistance measured by oscillometry with ventilation defects measured by Phase Resolved Functional Lung (PREFUL) MRI in healthy human subjects.
- Conditions
- Breathing, Lung Function Decreased, MRI Imaging, Healthy
- Trial name
- PROOF (NCT07614685)
- Testing
- Airway Oscillometer, Phase Resolved Functional Lung MRI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Rochester